| Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11 YS Hwang, BG Chung, D Ortmann, N Hattori, HC Moeller, ... Proceedings of the National Academy of Sciences 106 (40), 16978-16983, 2009 | 451 | 2009 |
| BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages AS Bernardo, T Faial, L Gardner, KK Niakan, D Ortmann, CE Senner, ... Cell stem cell 9 (2), 144-155, 2011 | 419 | 2011 |
| The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency A Bertero, S Brown, P Madrigal, A Osnato, D Ortmann, L Yiangou, ... Nature 555 (7695), 256-259, 2018 | 309 | 2018 |
| Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids F Sampaziotis, AW Justin, OC Tysoe, S Sawiak, EM Godfrey, SS Upponi, ... Nature medicine 23 (8), 954-963, 2017 | 262 | 2017 |
| Cholangiocyte organoids can repair bile ducts after transplantation in the human liver F Sampaziotis, D Muraro, OC Tysoe, S Sawiak, TE Beach, EM Godfrey, ... Science 371 (6531), 839-846, 2021 | 205 | 2021 |
| NANOG and CDX2 pattern distinct subtypes of human mesoderm during exit from pluripotency S Mendjan, VL Mascetti, D Ortmann, M Ortiz, DW Karjosukarso, Y Ng, ... Cell stem cell 15 (3), 310-325, 2014 | 199 | 2014 |
| Single-cell sequencing of developing human gut reveals transcriptional links to childhood Crohn’s disease R Elmentaite, ADB Ross, K Roberts, KR James, D Ortmann, T Gomes, ... Developmental cell 55 (6), 771-783. e5, 2020 | 180 | 2020 |
| Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells T Faial, AS Bernardo, S Mendjan, E Diamanti, D Ortmann, GE Gentsch, ... Development 142 (12), 2121-2135, 2015 | 162 | 2015 |
| Inducible and deterministic forward programming of human pluripotent stem cells into neurons, skeletal myocytes, and oligodendrocytes M Pawlowski, D Ortmann, A Bertero, JM Tavares, RA Pedersen, L Vallier, ... Stem cell reports 8 (4), 803-812, 2017 | 134 | 2017 |
| Variability of human pluripotent stem cell lines D Ortmann, L Vallier Current opinion in genetics & development 46, 179-185, 2017 | 124 | 2017 |
| Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs A Bertero, M Pawlowski, D Ortmann, K Snijders, L Yiangou, ... Development 143 (23), 4405-4418, 2016 | 91 | 2016 |
| Human axial progenitors generate trunk neural crest cells in vitro TJR Frith, I Granata, M Wind, E Stout, O Thompson, K Neumann, ... Elife 7, e35786, 2018 | 89 | 2018 |
| A hollow sphere soft lithography approach for long-term hanging drop methods WG Lee, D Ortmann, MJ Hancock, H Bae, A Khademhosseini Tissue Engineering Part C: Methods 16 (2), 249-259, 2010 | 64 | 2010 |
| Method to synchronize cell cycle of human pluripotent stem cells without affecting their fundamental characteristics L Yiangou, RA Grandy, CM Morell, RA Tomaz, A Osnato, J Kadiwala, ... Stem cell reports 12 (1), 165-179, 2019 | 47 | 2019 |
| Single-cell atlas of human liver development reveals pathways directing hepatic cell fates BT Wesley, ADB Ross, D Muraro, Z Miao, S Saxton, RA Tomaz, CM Morell, ... Nature Cell Biology 24 (10), 1487-1498, 2022 | 42 | 2022 |
| Naive pluripotent stem cells exhibit phenotypic variability that is driven by genetic variation D Ortmann, S Brown, A Czechanski, S Aydin, D Muraro, Y Huang, ... Cell stem cell 27 (3), 470-481. e6, 2020 | 40 | 2020 |
| Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation G Canu, E Athanasiadis, RA Grandy, J Garcia-Bernardo, PM Strzelecka, ... Genome biology 21, 1-28, 2020 | 38 | 2020 |
| Methods for embryoid body formation: the microwell approach DP Spelke, D Ortmann, A Khademhosseini, L Ferreira, JM Karp Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and …, 2011 | 34 | 2011 |
| TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells A Osnato, S Brown, C Krueger, S Andrews, AJ Collier, S Nakanoh, ... Elife 10, e67259, 2021 | 31 | 2021 |
| A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels Y Xing, S Zhao, Q Wei, S Gong, X Zhao, F Zhou, AIL Rafia, D Ortmann, ... European Respiratory Journal 51 (4), 2018 | 23 | 2018 |
