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Karin van Schie
Karin van Schie
Leiden University Medical Center
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Response to:'The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region’by Rinaudo-Gaujous et al
KA Van Schie, MH Hart, ER de Groot, S Kruithof, LA Aarden, GJ Wolbink, ...
Annals of the Rheumatic Diseases 74 (8), e41-e41, 2015
149*2015
The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region
KA van Schie, MH Hart, ER de Groot, S Kruithof, LA Aarden, GJ Wolbink, ...
Annals of the rheumatic diseases 74 (1), 311-314, 2015
1452015
Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology
M Volkov, KA van Schie, D van der Woude
Immunological Reviews 294 (1), 148-163, 2020
1362020
Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region
FS Van De Bovenkamp, NIL Derksen, P Ooijevaar-de Heer, KA Van Schie, ...
Proceedings of the National Academy of Sciences 115 (8), 1901-1906, 2018
1152018
Cross-reactive and pre-existing antibodies to therapeutic antibodies—effects on treatment and immunogenicity
KA van Schie, GJ Wolbink, T Rispens
MAbs 7 (4), 662-671, 2015
982015
Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies
PA van Schouwenburg, S Kruithof, C Votsmeier, K van Schie, MH Hart, ...
Journal of Biological Chemistry 289 (50), 34482-34488, 2014
632014
Therapeutic TNF inhibitors can differentially stabilize trimeric TNF by inhibiting monomer exchange
KA van Schie, P Ooijevaar-de Heer, L Dijk, S Kruithof, G Wolbink, ...
Scientific reports 6 (1), 32747, 2016
592016
On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis
T Kissel, KA van Schie, L Hafkenscheid, A Lundquist, H Kokkonen, ...
Annals of the rheumatic diseases 78 (12), 1616-1620, 2019
482019
TNF-anti-TNF immune complexes inhibit IL-12/IL-23 secretion by inflammatory macrophages via an fc-dependent mechanism
FM Bloemendaal, PJ Koelink, KA van Schie, T Rispens, CP Peters, ...
Journal of Crohn's and Colitis 12 (9), 1122-1130, 2018
432018
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation
T Kissel, C Ge, L Hafkenscheid, JC Kwekkeboom, LM Slot, M Cavallari, ...
Science advances 8 (6), eabm1759, 2022
342022
A transductionally retargeted adenoviral vector for virotherapy of Her2/neu-expressing prostate cancer
MK Magnusson, R Kraaij, RM Leadley, CMA De Ridder, ...
Human gene therapy 23 (1), 70-82, 2012
282012
Neutralizing capacity of monoclonal and polyclonal anti-natalizumab antibodies: The immune response to antibody therapeutics preferentially targets the antigen-binding site
KA van Schie, S Kruithof, PA van Schouwenburg, A Vennegoor, ...
Journal of Allergy and Clinical Immunology 139 (3), 1035-1037. e6, 2017
272017
Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies
KA van Schie, S Kruithof, P Ooijevaar-de Heer, NIL Derksen, ...
Annals of the rheumatic diseases 77 (10), 1471-1479, 2018
252018
Infusion reactions during infliximab treatment are not associated with IgE anti-infliximab antibodies
KA van Schie, P Ooijevaar-De Heer, S Kruithof, C Plasencia, T Jurado, ...
Annals of the rheumatic diseases 76 (7), 1285-1288, 2017
172017
Comprehensive overview of autoantibody isotype and subclass distribution
M Volkov, M Coppola, R Huizinga, F Eftimov, TWJ Huizinga, ...
Journal of Allergy and Clinical Immunology 150 (5), 999-1010, 2022
162022
Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications
M Volkov, ASB Kampstra, KA van Schie, A Kawakami, M Tamai, ...
Arthritis Research & Therapy 23 (1), 1-10, 2021
72021
IgG Fab Glycans Hinder FcRn-Mediated Placental Transport
M Volkov, M Brinkhaus, KA van Schie, A Bondt, T Kissel, EJ van der Kooi, ...
The Journal of Immunology 210 (2), 158-167, 2023
62023
Multifunctional, multivalent PIC polymer scaffolds for targeting antigen-specific, autoreactive B cells
H Kristyanto, MD Holborough-Kerkvliet, L Lelieveldt, Y Bartels, ...
ACS Biomaterials Science & Engineering 8 (4), 1486-1493, 2022
62022
AB0020 ACPA ILLUSTRATING THE IMPACT OF IGG FAB-GLYCOSYLATION ON TRANSPLACENTAL TRANSFER OF ANTIBODIES AND THEIR BINDING TO THE NEONATAL FC-RECEPTOR (FCRN)
M Volkov, K Van Schie, A Bondt, T Kissel, M Brinkhaus, A Bentlage, ...
Annals of the Rheumatic Diseases 80 (Suppl 1), 1044-1044, 2021
22021
POS0384 A NOVEL MECHANISM LINKING MUCOSAL BACTERIA WITH AUTOANTIBODY RESPONSES IN RA: ACETYLATED BACTERIAL LYSATE AS A MODEL ANTIGEN
M Volkov, ASB Kampstra, K van Schie, J Kwekkeboom, T Huizinga, ...
Annals of the Rheumatic Diseases 80 (Suppl 1), 422-422, 2021
12021
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