Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease C Besler, K Heinrich, L Rohrer, C Doerries, M Riwanto, DM Shih, A Chroni, ... The Journal of clinical investigation 121 (7), 2693-2708, 2011 | 648 | 2011 |
Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL VI Zannis, A Chroni, M Krieger Journal of molecular medicine 84, 276-294, 2006 | 512 | 2006 |
ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux ML Fitzgerald, AL Morris, A Chroni, AJ Mendez, VI Zannis, MW Freeman Journal of lipid research 45 (2), 287-294, 2004 | 190 | 2004 |
The central helices of ApoA-I can promote ATP-Binding Cassette Transporter A1 (ABCA1)-mediated Lipid efflux: amino acid residues 220–231 of the wild-type ApoA-I are required … A Chroni, T Liu, I Gorshkova, HY Kan, Y Uehara, A Von Eckardstein, ... Journal of Biological Chemistry 278 (9), 6719-6730, 2003 | 156 | 2003 |
Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1 A Chroni, T Liu, ML Fitzgerald, MW Freeman, VI Zannis Biochemistry 43 (7), 2126-2139, 2004 | 137 | 2004 |
HDL biogenesis, remodeling, and catabolism VI Zannis, P Fotakis, G Koukos, D Kardassis, C Ehnholm, M Jauhiainen, ... Handb Exp Pharmacol 224, 53-111, 2015 | 136 | 2015 |
The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1 I Evnouchidou, F Momburg, A Papakyriakou, A Chroni, L Leondiadis, ... PloS one 3 (11), e3658, 2008 | 129 | 2008 |
Specific mutations in ABCA1 have discrete effects on ABCA1 function and lipid phenotypes both in vivo and in vitro RR Singaraja, H Visscher, ER James, A Chroni, JM Coutinho, ... Circulation research 99 (4), 389-397, 2006 | 129 | 2006 |
Cross-inhibition of SR-BI-and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide TJF Nieland, A Chroni, ML Fitzgerald, Z Maliga, VI Zannis, T Kirchhausen, ... Journal of lipid research 45 (7), 1256-1265, 2004 | 105 | 2004 |
Probing the pathways of chylomicron and HDL metabolism using adenovirus-mediated gene transfer VI Zannis, A Chroni, KE Kypreos, HY Kan, TB Cesar, EE Zanni, ... Current opinion in lipidology 15 (2), 151-166, 2004 | 94 | 2004 |
Lipoproteins and atherogenesis VI Zannis, KE Kypreos, A Chroni, D Kardassis, EE Zanni Molecular mechanisms of atherosclerosis 8, 111-174, 2004 | 73 | 2004 |
Structure and stability of apolipoprotein AI in solution and in discoidal high-density lipoprotein probed by double charge ablation and deletion mutation IN Gorshkova, T Liu, HY Kan, A Chroni, VI Zannis, D Atkinson Biochemistry 45 (4), 1242-1254, 2006 | 64 | 2006 |
SR-BI mediates cholesterol efflux via its interactions with lipid-bound ApoE. Structural mutations in SR-BI diminish cholesterol efflux A Chroni, TJF Nieland, KE Kypreos, M Krieger, VI Zannis Biochemistry 44 (39), 13132-13143, 2005 | 62 | 2005 |
Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1 D Georgiadou, A Hearn, I Evnouchidou, A Chroni, L Leondiadis, IA York, ... The Journal of Immunology 185 (3), 1584-1592, 2010 | 58 | 2010 |
Characterization of antioxidant/anti-inflammatory properties and apoA-I-containing subpopulations of HDL from family subjects with monogenic low HDL disorders G Daniil, AAP Phedonos, AG Holleboom, MM Motazacker, L Argyri, ... Clinica chimica acta 412 (13-14), 1213-1220, 2011 | 56 | 2011 |
Substitutions of glutamate 110 and 111 in the middle helix 4 of human apolipoprotein AI (apoA-I) by alanine affect the structure and in vitro functions of apoA-I and induce … A Chroni, HY Kan, KE Kypreos, IN Gorshkova, A Shkodrani, VI Zannis Biochemistry 43 (32), 10442-10457, 2004 | 56 | 2004 |
Effects of bariatric surgery on HDL structure and functionality: results from a prospective trial E Zvintzou, G Skroubis, A Chroni, PI Petropoulou, C Gkolfinopoulou, ... Journal of Clinical Lipidology 8 (4), 408-417, 2014 | 50 | 2014 |
An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42 I Dafnis, E Stratikos, A Tzinia, EC Tsilibary, VI Zannis, A Chroni Journal of neurochemistry 115 (4), 873-884, 2010 | 44 | 2010 |
Point mutations in apolipoprotein aI mimic the phenotype observed in patients with classical lecithin: cholesterol acyltransferase deficiency A Chroni, A Duka, HY Kan, T Liu, VI Zannis Biochemistry 44 (43), 14353-14366, 2005 | 42 | 2005 |
The carboxy-terminal region of apoA-I is required for the ABCA1-dependent formation of α-HDL but not preβ-HDL particles in vivo A Chroni, G Koukos, A Duka, VI Zannis Biochemistry 46 (19), 5697-5708, 2007 | 40 | 2007 |