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Patrick Deelen
Patrick Deelen
Post-doc researcher at University Medical Center Groningen
Verified email at umcg.nl - Homepage
Title
Cited by
Cited by
Year
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
A Zhernakova, A Kurilshikov, MJ Bonder, EF Tigchelaar, M Schirmer, ...
Science 352 (6285), 565-569, 2016
17422016
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
7962021
The effect of host genetics on the gut microbiome
MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ...
Nature genetics 48 (11), 1407-1412, 2016
7642016
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7372021
Whole-genome sequence variation, population structure and demographic history of the Dutch population
Nature genetics 46 (8), 818-825, 2014
7152014
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ...
Nature communications 9 (1), 2941, 2018
7082018
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ...
Nature genetics 51 (2), 245-257, 2019
5972019
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
4942018
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
4542017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
4482017
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA
RSN Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, ...
PLoS genetics 7 (8), e1002197, 2011
4352011
The Genome of the Netherlands: design, and project goals
DI Boomsma, C Wijmenga, EP Slagboom, MA Swertz, LC Karssen, ...
European journal of human genetics 22 (2), 221-227, 2014
3272014
Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
MGP Van Der Wijst, H Brugge, DH De Vries, P Deelen, MA Swertz, ...
Nature genetics 50 (4), 493-497, 2018
3232018
A functional genomics approach to understand variation in cytokine production in humans
Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ...
Cell 167 (4), 1099-1110. e14, 2016
3192016
Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution
M van Iterson, EW van Zwet, Bios Consortium, BT Heijmans
Genome biology 18, 1-13, 2017
2942017
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ...
Nature genetics 53 (12), 1636-1648, 2021
2922021
Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics
EF Tigchelaar, A Zhernakova, JAM Dekens, G Hermes, A Baranska, ...
BMJ open 5 (8), e006772, 2015
2812015
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
J Fu, MGM Wolfs, P Deelen, HJ Westra, RSN Fehrmann, GJ Te Meerman, ...
PLoS genetics 8 (1), e1002431, 2012
2782012
Whole-genome sequencing reveals host factors underlying critical COVID-19
A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ...
Nature 607 (7917), 97-103, 2022
2332022
Genetic insights into biological mechanisms governing human ovarian ageing
KS Ruth, FR Day, J Hussain, A Martínez-Marchal, CE Aiken, A Azad, ...
Nature 596 (7872), 393-397, 2021
2262021
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