Patrick Deelen
Patrick Deelen
Post-doc researcher at University Medical Center Groningen
Geverifieerd e-mailadres voor umcg.nl - Homepage
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Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
A Zhernakova, A Kurilshikov, MJ Bonder, EF Tigchelaar, M Schirmer, ...
Science 352 (6285), 565-569, 2016
7812016
Whole-genome sequence variation, population structure and demographic history of the Dutch population
LC Francioli, A Menelaou, SL Pulit, F Van Dijk, PF Palamara, CC Elbers, ...
Nature genetics 46 (8), 818, 2014
5052014
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
RSN Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, ...
PLoS Genet 7 (8), e1002197, 2011
3612011
The effect of host genetics on the gut microbiome
MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ...
Nature genetics 48 (11), 1407-1412, 2016
3402016
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
J Fu, MGM Wolfs, P Deelen, HJ Westra, RSN Fehrmann, GJ Te Meerman, ...
PLoS Genet 8 (1), e1002431, 2012
2242012
The Genome of the Netherlands: design, and project goals
DI Boomsma, C Wijmenga, EP Slagboom, MA Swertz, LC Karssen, ...
European Journal of Human Genetics 22 (2), 221-227, 2014
2152014
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
2132017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
2092017
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ...
Nature communications 9 (1), 1-14, 2018
1482018
Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics
EF Tigchelaar, A Zhernakova, JAM Dekens, G Hermes, A Baranska, ...
BMJ open 5 (8), 2015
1242015
A functional genomics approach to understand variation in cytokine production in humans
Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ...
Cell 167 (4), 1099-1110. e14, 2016
1202016
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
1112018
Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi
Y Li, M Oosting, P Deelen, I Ricańo-Ponce, S Smeekens, M Jaeger, ...
Nature medicine 22 (8), 952-960, 2016
982016
Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
MGP van der Wijst, H Brugge, DH de Vries, P Deelen, MA Swertz, ...
Nature genetics 50 (4), 493-497, 2018
942018
Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’
P Deelen, A Menelaou, EM Van Leeuwen, A Kanterakis, F Van Dijk, ...
European Journal of Human Genetics 22 (11), 1321-1326, 2014
932014
Genetic and epigenetic regulation of gene expression in fetal and adult human livers
MJ Bonder, S Kasela, M Kals, R Tamm, K Lokk, I Barragan, WA Buurman, ...
BMC genomics 15 (1), 860, 2014
832014
A proteomics and transcriptomics approach to identify leukemic stem cell (LSC) markers
F Bonardi, F Fusetti, P Deelen, D van Gosliga, E Vellenga, JJ Schuringa
Molecular & Cellular Proteomics 12 (3), 626-637, 2013
712013
Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration
P Deelen, MJ Bonder, KJ van der Velde, HJ Westra, E Winder, ...
BMC research notes 7 (1), 901, 2014
612014
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants
JY Hehir-Kwa, T Marschall, WP Kloosterman, LC Francioli, JA Baaijens, ...
Nature communications 7 (1), 1-10, 2016
592016
Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms
RC Slieker, M van Iterson, R Luijk, M Beekman, DV Zhernakova, ...
Genome biology 17 (1), 1-13, 2016
572016
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Artikelen 1–20