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Filippos Kesisoglou
Filippos Kesisoglou
Distinguished Scientist, Pharmaceutical Sciences, Merck & Co., Inc.
Geverifieerd e-mailadres voor merck.com
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Nanosizing—oral formulation development and biopharmaceutical evaluation
F Kesisoglou, S Panmai, Y Wu
Advanced drug delivery reviews 59 (7), 631-644, 2007
12002007
Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling
Y Shono, E Jantratid, N Janssen, F Kesisoglou, Y Mao, M Vertzoni, ...
European Journal of Pharmaceutics and Biopharmaceutics 73 (1), 107-114, 2009
1802009
Understanding the effect of API properties on bioavailability through absorption modeling
F Kesisoglou, Y Wu
The AAPS journal 10, 516-525, 2008
1542008
Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans
Y Shono, E Jantratid, F Kesisoglou, C Reppas, JB Dressman
European journal of pharmaceutics and biopharmaceutics 76 (1), 95-104, 2010
1422010
In vitro models for the prediction of in vivo performance of oral dosage forms: recent progress from partnership through the IMI OrBiTo collaboration
J Butler, B Hens, M Vertzoni, J Brouwers, P Berben, J Dressman, ...
European Journal of Pharmaceutics and Biopharmaceutics 136, 70-83, 2019
1172019
Evolution of choice of solubility and dissolution media after two decades of biopharmaceutical classification system
N Bou-Chacra, KJC Melo, IAC Morales, ES Stippler, F Kesisoglou, ...
The AAPS journal 19 (4), 989-1001, 2017
1122017
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Z Vinarov, B Abrahamsson, P Artursson, H Batchelor, P Berben, ...
Advanced drug delivery reviews 171, 289-331, 2021
992021
Impaired drug absorption due to high stomach pH: a review of strategies for mitigation of such effect to enable pharmaceutical product development
A Mitra, F Kesisoglou
Molecular pharmaceutics 10 (11), 3970-3979, 2013
982013
Application of nanoparticles in oral delivery of immediate release formulations
F Kesisoglou, S Panmai, Y Wu
Current Nanoscience 3 (2), 183-190, 2007
952007
Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based …
C Wagner, E Jantratid, F Kesisoglou, M Vertzoni, C Reppas, JB Dressman
European journal of pharmaceutics and biopharmaceutics 82 (1), 127-138, 2012
932012
Industry's view on using quality control, biorelevant, and clinically relevant dissolution tests for pharmaceutical development, registration, and commercialization
H Grady, D Elder, GK Webster, Y Mao, Y Lin, T Flanagan, J Mann, ...
Journal of Pharmaceutical Sciences 107 (1), 34-41, 2018
832018
Characteristics of the human upper gastrointestinal contents in the fasted state under hypo-and A-chlorhydric gastric conditions under conditions of typical drug–drug …
C Litou, M Vertzoni, C Goumas, V Vasdekis, W Xu, F Kesisoglou, ...
Pharmaceutical research 33 (6), 1399-1412, 2016
812016
Dissolution and translational modeling strategies toward establishing an in vitro-in vivo link—a workshop summary report
T Heimbach, S Suarez-Sharp, M Kakhi, N Holmstock, A Olivares-Morales, ...
The AAPS Journal 21 (2), 1-15, 2019
772019
Amorphous solid dispersions or prodrugs: complementary strategies to increase drug absorption
ACF Rumondor, SS Dhareshwar, F Kesisoglou
Journal of pharmaceutical sciences 105 (9), 2498-2508, 2016
742016
Crystalline nanosuspensions as potential toxicology and clinical oral formulations for BCS II/IV compounds
F Kesisoglou, A Mitra
The AAPS journal 14 (4), 677-687, 2012
742012
Synthesis and study of alendronate derivatives as potential prodrugs of alendronate sodium for the treatment of low bone density and osteoporosis
P Vachal, JJ Hale, Z Lu, EC Streckfuss, SG Mills, M MacCoss, DH Yin, ...
Journal of medicinal chemistry 49 (11), 3060-3063, 2006
712006
Use of physiologically based pharmacokinetic (PBPK) modeling for predicting drug-food interactions: an industry perspective
AE Riedmaier, K DeMent, J Huckle, P Bransford, C Stillhart, R Lloyd, ...
The AAPS journal 22 (6), 1-15, 2020
702020
3D printed capsules for quantitative regional absorption studies in the GI tract
D Smith, Y Kapoor, A Hermans, R Nofsinger, F Kesisoglou, TP Gustafson, ...
International Journal of Pharmaceutics 550 (1-2), 418-428, 2018
692018
PBPK absorption modeling: establishing the in vitro–in vivo link—industry perspective
C Stillhart, X Pepin, C Tistaert, D Good, A Van Den Bergh, N Parrott, ...
The AAPS Journal 21 (2), 1-13, 2019
652019
Food effect projections via physiologically based pharmacokinetic modeling: predictive case studies
C Tistaert, T Heimbach, B Xia, N Parrott, TS Samant, F Kesisoglou
Journal of pharmaceutical sciences 108 (1), 592-602, 2019
642019
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