| A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family JS Smith, CB Brachmann, I Celic, MA Kenna, S Muhammad, VJ Starai, ... Proceedings of the National Academy of Sciences 97 (12), 6658-6663, 2000 | 939 | 2000 |
| An unusual form of transcriptional silencing in yeast ribosomal DNA. JS Smith, JD Boeke Genes & development 11 (2), 241-254, 1997 | 747 | 1997 |
| Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+ P Belenky, FG Racette, KL Bogan, JM McClure, JS Smith, C Brenner Cell 129 (3), 473-484, 2007 | 450 | 2007 |
| A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors JS Smith, E Caputo, JD Boeke Molecular and cellular biology 19 (4), 3184-3197, 1999 | 287 | 1999 |
| Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins DL Smith, Jr, JM McClure, M Matecic, JS Smith Aging cell 6 (5), 649-662, 2007 | 266 | 2007 |
| Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity CM Gallo, DL Smith Jr, JS Smith Molecular and cellular biology 24 (3), 1301-1312, 2004 | 257 | 2004 |
| A microarray-based genetic screen for yeast chronological aging factors M Matecic, DL Smith Jr, X Pan, N Maqani, S Bekiranov, JD Boeke, ... PLoS genetics 6 (4), e1000921, 2010 | 250 | 2010 |
| Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ... Molecular Metabolism 3, 114-123, 2013 | 232 | 2013 |
| Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p JS Smith, CB Brachmann, L Pillus, JD Boeke Genetics 149 (3), 1205-1219, 1998 | 206 | 1998 |
| Human Sir2 and the ‘silencing’of p53 activity JS Smith Trends in cell biology 12 (9), 404-406, 2002 | 187 | 2002 |
| RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase JJ Sandmeier, S French, Y Osheim, WL Cheung, CM Gallo, AL Beyer, ... The EMBO journal, 2002 | 176 | 2002 |
| Telomeric and rDNA Silencing in Saccharomyces cerevisiae Are Dependent on a Nuclear NAD+ Salvage Pathway JJ Sandmeier, I Celic, JD Boeke, JS Smith Genetics 160 (3), 877-889, 2002 | 154 | 2002 |
| The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae MR Gartenberg, JS Smith Genetics 203 (4), 1563-1599, 2016 | 136 | 2016 |
| Diversity in the Sir2 family of protein deacetylases SW Buck, CM Gallo, JS Smith Journal of Leucocyte Biology 75 (6), 939-950, 2004 | 131 | 2004 |
| DNA replication stress is a determinant of chronological lifespan in budding yeast M Weinberger, L Feng, A Paul, DL Smith Jr, RD Hontz, JS Smith, M Vujcic, ... PloS one 2 (8), e748, 2007 | 126 | 2007 |
| Yeast sirtuins and the regulation of aging MB Wierman, JS Smith FEMS yeast research 14 (1), 73-88, 2014 | 125 | 2014 |
| RNA polymerase I propagates unidirectional spreading of rDNA silent chromatin SW Buck, JJ Sandmeier, JS Smith Cell 111 (7), 1003-1014, 2002 | 120 | 2002 |
| Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes SL French, ML Sikes, RD Hontz, YN Osheim, TE Lambert, A El Hage, ... Molecular and cellular biology 31 (3), 482-494, 2011 | 106 | 2011 |
| Specificity of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H in removal of the minus-strand primer, tRNA (Lys3). JS Smith, MJ Roth Journal of Biological Chemistry 267 (21), 15071-15079, 1992 | 105 | 1992 |
| Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase NM Cirino, CE Cameron, JS Smith, MJ Roth, SJ Benkovic, SFJ Le Grice Biochemistry 34 (31), 9936-9943, 1995 | 101 | 1995 |
