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Jayme L Dahlin
Jayme L Dahlin
Brigham and Women's Hospital
Verified email at bwh.harvard.edu
Title
Cited by
Cited by
Year
The essential medicinal chemistry of curcumin: miniperspective
KM Nelson, JL Dahlin, J Bisson, J Graham, GF Pauli, MA Walters
Journal of medicinal chemistry 60 (5), 1620-1637, 2017
17672017
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
8332015
PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS
JL Dahlin, JWM Nissink, JM Strasser, S Francis, LA Higgins, H Zhou, ...
Journal of medicinal chemistry 58 (5), 2091-2113, 2015
3572015
Mitigating risk in academic preclinical drug discovery
JL Dahlin, J Inglese, MA Walters
Nature reviews Drug discovery 14 (4), 279-294, 2015
1772015
The essential roles of chemistry in high-throughput screening triage
JL Dahlin, MA Walters
Future medicinal chemistry 6 (11), 1265-1290, 2014
1562014
The essential medicinal chemistry of cannabidiol (CBD)
KM Nelson, J Bisson, G Singh, JG Graham, SN Chen, JB Friesen, ...
Journal of medicinal chemistry 63 (21), 12137-12155, 2020
1062020
Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors
JL Dahlin, KM Nelson, JM Strasser, D Barsyte-Lovejoy, MM Szewczyk, ...
Nature communications 8 (1), 1-14, 2017
1032017
How to triage PAINS-full research
JL Dahlin, MA Walters
Assay and drug development technologies 14 (3), 168-174, 2016
792016
Assay guidance manual [Internet]
S Markossian, A Grossman, K Brimacombe, M Arkin, D Auld, C Austin, ...
Eli Lilly & Company and the National Center for Advancing Translational Sciences, 2004
642004
GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity
D Menon, A Innes, AJ Oakley, JE Dahlstrom, LM Jensen, A Brüstle, ...
Scientific reports 7 (1), 17832, 2017
512017
Assay interference by chemical reactivity
JL Dahlin, J Baell, MA Walters
472015
Nuisance compounds in cellular assays
JL Dahlin, DS Auld, I Rothenaigner, S Haney, JZ Sexton, JWM Nissink, ...
Cell chemical biology 28 (3), 356-370, 2021
442021
Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery
NP Coussens, GS Sittampalam, R Guha, K Brimacombe, A Grossman, ...
Clinical and translational science 11 (5), 461-470, 2018
442018
Assay interference by aggregation
DS Auld, J Inglese, JL Dahlin
432017
Curcumin may (not) defy science
KM Nelson, JL Dahlin, J Bisson, J Graham, GF Pauli, MA Walters
ACS medicinal chemistry letters 8 (5), 467-470, 2017
422017
Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases
JL Dahlin, X Chen, MA Walters, Z Zhang
Critical reviews in biochemistry and molecular biology 50 (1), 31-53, 2015
422015
Microplate selection and recommended practices in high-throughput screening and quantitative biology
DS Auld, PA Coassin, NP Coussens, P Hensley, C Klumpp-Thomas, ...
Assay Guidance Manual [Internet], 2020
412020
Modeling small-molecule reactivity identifies promiscuous bioactive compounds
MK Matlock, TB Hughes, JL Dahlin, SJ Swamidass
Journal of chemical information and modeling 58 (8), 1483-1500, 2018
392018
Atomistic Simulations of CO2 and N2 Diffusion in Silica Zeolites: The Impact of Pore Size and Shape
D Selassie, D Davis, J Dahlin, E Feise, G Haman, DS Sholl, D Kohen
The Journal of Physical Chemistry C 112 (42), 16521-16531, 2008
352008
A cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylation
JL Dahlin, R Sinville, J Solberg, H Zhou, J Han, S Francis, JM Strasser, ...
PLoS One 8 (11), e78877, 2013
292013
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Articles 1–20