Transcriptome and genome sequencing uncovers functional variation in humans T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ... Nature 501 (7468), 506-511, 2013 | 2044 | 2013 |
Effect of predicted protein-truncating genetic variants on the human transcriptome MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ... Science 348 (6235), 666-669, 2015 | 341 | 2015 |
Low-avidity CD4+ T cell responses to SARS-CoV-2 in unexposed individuals and humans with severe COVID-19 P Bacher, E Rosati, D Esser, GR Martini, C Saggau, E Schiminsky, ... Immunity 53 (6), 1258-1271. e5, 2020 | 278 | 2020 |
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 197 | 2019 |
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells L Niederreiter, TMJ Fritz, TE Adolph, AM Krismer, FA Offner, ... Journal of Experimental Medicine 210 (10), 2041-2056, 2013 | 152 | 2013 |
Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly P Aramillo Irizar, S Schäuble, D Esser, M Groth, C Frahm, S Priebe, ... Nature communications 9 (1), 327, 2018 | 114 | 2018 |
Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease R Häsler, R Sheibani-Tezerji, A Sinha, M Barann, A Rehman, D Esser, ... Gut 66 (12), 2087-2097, 2017 | 86 | 2017 |
Functions of the microbiota for the physiology of animal metaorganisms D Esser, J Lange, G Marinos, M Sieber, L Best, D Prasse, J Bathia, ... Journal of innate immunity 11 (5), 393-404, 2019 | 77 | 2019 |
Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae JM Greenwood, B Milutinović, R Peuß, S Behrens, D Esser, P Rosenstiel, ... BMC genomics 18, 1-14, 2017 | 64 | 2017 |
Infection routes matter in population-specific responses of the red flour beetle to the entomopathogen Bacillus thuringiensis S Behrens, R Peuß, B Milutinović, H Eggert, D Esser, P Rosenstiel, ... BMC genomics 15, 1-17, 2014 | 63 | 2014 |
Epithelial RNase H2 maintains genome integrity and prevents intestinal tumorigenesis in mice K Aden, K Bartsch, J Dahl, MAM Reijns, D Esser, R Sheibani-Tezerji, ... Gastroenterology 156 (1), 145-159. e19, 2019 | 55 | 2019 |
Next‐generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN‐amplified neuroblastoma A Schramm, J Köster, T Marschall, M Martin, M Schwermer, K Fielitz, ... International journal of cancer 132 (3), E106-E115, 2013 | 45 | 2013 |
Overlapping and unique signatures in the proteomic and transcriptomic responses of the nematode Caenorhabditis elegans toward pathogenic Bacillus thuringiensis W Yang, K Dierking, D Esser, A Tholey, M Leippe, P Rosenstiel, ... Developmental & Comparative Immunology 51 (1), 1-9, 2015 | 43 | 2015 |
Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing B Kreck, J Richter, O Ammerpohl, M Barann, D Esser, BS Petersen, I Vater, ... Leukemia 27 (8), 1751-1753, 2013 | 36 | 2013 |
Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal … A Fabian, S Stegner, L Miarka, J Zimmermann, L Lenk, S Rahn, J Buttlar, ... Cancer letters 453, 95-106, 2019 | 29 | 2019 |
Interpreting whole genome and exome sequencing data of individual gastric cancer samples D Esser, N Holze, J Haag, S Schreiber, S Krüger, V Warneke, ... BMC genomics 18, 1-15, 2017 | 15 | 2017 |
B-cell-depletion reverses dysbiosis of the microbiome in multiple sclerosis patients A Troci, O Zimmermann, D Esser, P Krampitz, S May, A Franke, D Berg, ... Scientific Reports 12 (1), 3728, 2022 | 14 | 2022 |
Pre-existing T cell memory as a risk factor for severe COVID-19 in the elderly P Bacher, E Rosati, D Esser, GR Martini, C Saggau, E Schiminsky, ... MedRxiv, 2020.09. 15.20188896, 2020 | 13 | 2020 |
Cerebrospinal fluid proteomics indicates immune dysregulation and neuronal dysfunction in antibody associated autoimmune encephalitis S Räuber, CB Schroeter, C Strippel, C Nelke, T Ruland, A Dik, ... Journal of autoimmunity 135, 102985, 2023 | 3 | 2023 |
Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models M Kaehler, P Osteresch, A Künstner, SJ Vieth, D Esser, M Möller, H Busch, ... Frontiers in Oncology 13, 1200897, 2023 | 2 | 2023 |