| Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes M Bantscheff, C Hopf, MM Savitski, A Dittmann, P Grandi, AM Michon, ... Nature biotechnology 29 (3), 255-265, 2011 | 790 | 2011 |
| Systematic analysis of protein turnover in primary cells T Mathieson, H Franken, J Kosinski, N Kurzawa, N Zinn, G Sweetman, ... Nature communications 9 (1), 689, 2018 | 350 | 2018 |
| Measuring and managing ratio compression for accurate iTRAQ/TMT quantification MM Savitski, T Mathieson, N Zinn, G Sweetman, C Doce, I Becher, ... Journal of proteome research 12 (8), 3586-3598, 2013 | 302 | 2013 |
| Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat I Becher, T Werner, C Doce, EA Zaal, I Tögel, CA Khan, A Rueger, ... Nature chemical biology 12 (11), 908-910, 2016 | 246 | 2016 |
| Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition NH Theodoulou, P Bamborough, AJ Bannister, I Becher, RA Bit, KH Che, ... Journal of medicinal chemistry 59 (4), 1425-1439, 2016 | 238 | 2016 |
| High-resolution enabled TMT 8-plexing T Werner, I Becher, G Sweetman, C Doce, MM Savitski, M Bantscheff Analytical chemistry 84 (16), 7188-7194, 2012 | 238 | 2012 |
| Pervasive protein thermal stability variation during the cell cycle I Becher, A Andrés-Pons, N Romanov, F Stein, M Schramm, F Baudin, ... Cell 173 (6), 1495-1507. e18, 2018 | 223 | 2018 |
| Meltome atlas—thermal proteome stability across the tree of life A Jarzab, N Kurzawa, T Hopf, M Moerch, J Zecha, N Leijten, Y Bian, ... Nature methods 17 (5), 495-503, 2020 | 218 | 2020 |
| Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ... Cell 173 (1), 260-274. e25, 2018 | 214 | 2018 |
| Thermal proteome profiling for interrogating protein interactions A Mateus, N Kurzawa, I Becher, S Sridharan, D Helm, F Stein, A Typas, ... Molecular systems biology 16 (3), e9232, 2020 | 207 | 2020 |
| Identifying drug targets in tissues and whole blood with thermal-shift profiling J Perrin, T Werner, N Kurzawa, A Rutkowska, DD Childs, M Kalxdorf, ... Nature Biotechnology 38 (3), 303-308, 2020 | 150 | 2020 |
| Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics D Helm, JPC Vissers, CJ Hughes, H Hahne, B Ruprecht, F Pachl, A Grzyb, ... Molecular & Cellular Proteomics 13 (12), 3709-3715, 2014 | 127 | 2014 |
| Functional interdependence of BRD4 and DOT1L in MLL leukemia O Gilan, EYN Lam, I Becher, D Lugo, E Cannizzaro, G Joberty, A Ward, ... Nature structural & molecular biology 23 (7), 673-681, 2016 | 108 | 2016 |
| Impact of phosphorylation on thermal stability of proteins CM Potel, N Kurzawa, I Becher, A Typas, A Mateus, MM Savitski Nature methods 18 (7), 757-759, 2021 | 91 | 2021 |
| Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP I Becher, MM Savitski, MF Savitski, C Hopf, M Bantscheff, G Drewes ACS chemical biology 8 (3), 599-607, 2013 | 88 | 2013 |
| Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane M Kalxdorf, I Günthner, I Becher, N Kurzawa, S Knecht, MM Savitski, ... Nature Methods 18 (1), 84-91, 2021 | 69 | 2021 |
| GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain P Bamborough, HA Barnett, I Becher, MJ Bird, C Chung, PD Craggs, ... ACS medicinal chemistry letters 7 (6), 552-557, 2016 | 66 | 2016 |
| Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes I Becher, A Dittmann, MM Savitski, C Hopf, G Drewes, M Bantscheff ACS chemical biology 9 (8), 1736-1746, 2014 | 62 | 2014 |
| A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ... Nature communications 11 (1), 5783, 2020 | 43 | 2020 |
| H-score, a mass accuracy driven rescoring approach for improved peptide identification in modification rich samples MM Savitski, T Mathieson, I Becher, M Bantscheff Journal of proteome research 9 (11), 5511-5516, 2010 | 41 | 2010 |
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