Roderick Slieker
Roderick Slieker
Computational biologist @ LUMC
Verified email at
Cited by
Cited by
DNA methylation signatures link prenatal famine exposure to growth and metabolism
EW Tobi, JJ Goeman, R Monajemi, H Gu, H Putter, Y Zhang, RC Slieker, ...
Nature communications 5 (1), 5592, 2014
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease
E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ...
Cell stem cell 26 (6), 862-879. e11, 2020
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
A reference map of potential determinants for the human serum metabolome
N Bar, T Korem, O Weissbrod, D Zeevi, D Rothschild, S Leviatan, ...
Nature 588 (7836), 135-140, 2020
DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood
EW Tobi, RC Slieker, R Luijk, KF Dekkers, AD Stein, KM Xu, ...
Science advances 4 (1), eaao4364, 2018
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
RC Slieker, SD Bos, JJ Goeman, JVMG Bovée, RP Talens, ...
Epigenetics & chromatin 6, 1-12, 2013
Zebrafish as potential model for developmental neurotoxicity testing: a mini review
C De Esch, R Slieker, A Wolterbeek, R Woutersen, D de Groot
Neurotoxicology and teratology 34 (6), 545-553, 2012
Blood lipids influence DNA methylation in circulating cells
KF Dekkers, M van Iterson, RC Slieker, MH Moed, MJ Bonder, ...
Genome biology 17, 1-12, 2016
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
EW Tobi, RC Slieker, AD Stein, HED Suchiman, PE Slagboom, ...
International journal of epidemiology 44 (4), 1211-1223, 2015
MethylAid: visual and interactive quality control of large Illumina 450k datasets
M Van Iterson, EW Tobi, RC Slieker, W Den Hollander, R Luijk, ...
Bioinformatics 30 (23), 3435-3437, 2014
Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception
RC Slieker, CL Relton, TR Gaunt, PE Slagboom, BT Heijmans
Epigenetics & chromatin 11, 1-11, 2018
Alternative routes to induce naive pluripotency in human embryonic stem cells
G Duggal, S Warrier, S Ghimire, D Broekaert, M Van der Jeught, ...
Stem cells 33 (9), 2686-2698, 2015
Locomotor activity assay in zebrafish larvae: influence of age, strain and ethanol
C de Esch, H van der Linde, R Slieker, R Willemsen, A Wolterbeek, ...
Neurotoxicology and teratology 34 (4), 425-433, 2012
Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms
RC Slieker, M van Iterson, R Luijk, M Beekman, DV Zhernakova, ...
Genome biology 17, 1-13, 2016
DNA methylation landscapes of human fetal development
RC Slieker, MS Roost, L van Iperen, HED Suchiman, EW Tobi, F Carlotti, ...
PLoS genetics 11 (10), e1005583, 2015
Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER
HED Suchiman, RC Slieker, D Kremer, PE Slagboom, BT Heijmans, ...
Frontiers in genetics 6, 287, 2015
Early-and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn
EM Herzog, AJ Eggink, SP Willemsen, RC Slieker, KPJ Wijnands, JF Felix, ...
Placenta 58, 122-132, 2017
Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process
MG Bacalini, J Deelen, C Pirazzini, M De Cecco, C Giuliani, C Lanzarini, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017
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