Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death CR Bezzina, J Barc, Y Mizusawa, CA Remme, JB Gourraud, F Simonet, ... Nature genetics 45 (9), 1044-1049, 2013 | 560 | 2013 |
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and … R Coronel, S Casini, TT Koopmann, FJG Wilms-Schopman, AO Verkerk, ... Circulation 112 (18), 2769-2777, 2005 | 535 | 2005 |
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria WMH Hoogaars, A Engel, JF Brons, AO Verkerk, FJ de Lange, LYE Wong, ... Genes & development 21 (9), 1098-1112, 2007 | 488 | 2007 |
Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology HD Devalla, V Schwach, JW Ford, JT Milnes, S El‐Haou, C Jackson, ... EMBO molecular medicine 7 (4), 394-410, 2015 | 340 | 2015 |
Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem? CC Veerman, G Kosmidis, CL Mummery, S Casini, AO Verkerk, M Bellin Stem cells and development 24 (9), 1035-1052, 2015 | 308 | 2015 |
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease RP Davis, S Casini, CW van den Berg, M Hoekstra, CA Remme, ... Circulation 125 (25), 3079-3091, 2012 | 308 | 2012 |
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells MJ Birket, MC Ribeiro, AO Verkerk, D Ward, AR Leitoguinho, ... Nature biotechnology 33 (9), 970-979, 2015 | 249 | 2015 |
Intercalated disc abnormalities, reduced Na+ current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes S Rizzo, EM Lodder, AO Verkerk, R Wolswinkel, L Beekman, K Pilichou, ... Cardiovascular research 95 (4), 409-418, 2012 | 239 | 2012 |
Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias M Hoekstra, CL Mummery, AAM Wilde, CR Bezzina, AO Verkerk Frontiers in physiology 3, 346, 2012 | 235 | 2012 |
Overlap Syndrome of Cardiac Sodium Channel Disease in Mice Carrying the Equivalent Mutation of Human SCN5A-1795insD CA Remme, AO Verkerk, D Nuyens, ACG van Ginneken, S van Brunschot, ... Circulation 114 (24), 2584-2594, 2006 | 226 | 2006 |
Identification and functional characterization of cardiac pacemaker cells in zebrafish F Tessadori, JH van Weerd, SB Burkhard, AO Verkerk, E de Pater, ... Public Library of Science 7 (10), e47644, 2012 | 217 | 2012 |
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization CR Bezzina, AO Verkerk, A Busjahn, A Jeron, J Erdmann, TT Koopmann, ... Cardiovascular research 59 (1), 27-36, 2003 | 217 | 2003 |
HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy A Milano, AMC Vermeer, EM Lodder, J Barc, AO Verkerk, AV Postma, ... Journal of the American College of Cardiology 64 (8), 745-756, 2014 | 211 | 2014 |
Genetic control of sodium channel function HL Tan, CR Bezzina, JPP Smits, AO Verkerk, AAM Wilde Cardiovascular research 57 (4), 961-973, 2003 | 208 | 2003 |
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue M Zhang, C D’Aniello, AO Verkerk, E Wrobel, S Frank, ... Proceedings of the National Academy of Sciences 111 (50), E5383-E5392, 2014 | 205 | 2014 |
Pacemaker current (If) in the human sinoatrial node AO Verkerk, R Wilders, MMGJ van Borren, RJG Peters, E Broekhuis, ... European heart journal 28 (20), 2472-2478, 2007 | 200 | 2007 |
RBM20 mutations induce an arrhythmogenic dilated cardiomyopathy related to disturbed calcium handling MMG van den Hoogenhof, A Beqqali, AS Amin, I van der Made, S Aufiero, ... Circulation 138 (13), 1330-1342, 2018 | 198 | 2018 |
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells ML Bakker, GJJ Boink, BJ Boukens, AO Verkerk, M Van Den Boogaard, ... Cardiovascular research 94 (3), 439-449, 2012 | 183 | 2012 |
Functional NaV1.8 Channels in Intracardiac Neurons: The Link Between SCN10A and Cardiac Electrophysiology AO Verkerk, CA Remme, CA Schumacher, BP Scicluna, R Wolswinkel, ... Circulation research 111 (3), 333-343, 2012 | 169 | 2012 |
Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch MG Hoogendijk, M Potse, AC Linnenbank, AO Verkerk, HM den Ruijter, ... Heart rhythm 7 (2), 238-248, 2010 | 147 | 2010 |