Arie O. Verkerk
Arie O. Verkerk
Academic Medical Center, University of Amsterdam
Geverifieerd e-mailadres voor amsterdamumc.nl - Homepage
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Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
CR Bezzina, J Barc, Y Mizusawa, CA Remme, JB Gourraud, F Simonet, ...
Nature genetics 45 (9), 1044-1049, 2013
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and …
R Coronel, S Casini, TT Koopmann, FJG Wilms-Schopman, AO Verkerk, ...
Circulation 112 (18), 2769-2777, 2005
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria
WMH Hoogaars, A Engel, JF Brons, AO Verkerk, FJ de Lange, LYE Wong, ...
Genes & development 21 (9), 1098-1112, 2007
Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology
HD Devalla, V Schwach, JW Ford, JT Milnes, S El‐Haou, C Jackson, ...
EMBO molecular medicine 7 (4), 394-410, 2015
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease
RP Davis, S Casini, CW van den Berg, M Hoekstra, CA Remme, ...
Circulation 125 (25), 3079-3091, 2012
Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?
CC Veerman, G Kosmidis, CL Mummery, S Casini, AO Verkerk, M Bellin
Stem cells and development 24 (9), 1035-1052, 2015
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells
MJ Birket, MC Ribeiro, AO Verkerk, D Ward, AR Leitoguinho, ...
Nature biotechnology 33 (9), 970-979, 2015
Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias
M Hoekstra, CL Mummery, AAM Wilde, CR Bezzina, AO Verkerk
Frontiers in physiology 3, 346, 2012
Intercalated disc abnormalities, reduced Na+ current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes
S Rizzo, EM Lodder, AO Verkerk, R Wolswinkel, L Beekman, K Pilichou, ...
Cardiovascular research 95 (4), 409-418, 2012
Overlap Syndrome of Cardiac Sodium Channel Disease in Mice Carrying the Equivalent Mutation of Human SCN5A-1795insD
CA Remme, AO Verkerk, D Nuyens, ACG van Ginneken, S van Brunschot, ...
Circulation 114 (24), 2584-2594, 2006
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
CR Bezzina, AO Verkerk, A Busjahn, A Jeron, J Erdmann, TT Koopmann, ...
Cardiovascular research 59 (1), 27-36, 2003
Identification and functional characterization of cardiac pacemaker cells in zebrafish
F Tessadori, JH van Weerd, SB Burkhard, AO Verkerk, E de Pater, ...
Public Library of Science 7 (10), e47644, 2012
HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy
A Milano, AMC Vermeer, EM Lodder, J Barc, AO Verkerk, AV Postma, ...
Journal of the American College of Cardiology 64 (8), 745-756, 2014
Genetic control of sodium channel function
HL Tan, CR Bezzina, JPP Smits, AO Verkerk, AAM Wilde
Cardiovascular research 57 (4), 961-973, 2003
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue
M Zhang, C D’Aniello, AO Verkerk, E Wrobel, S Frank, ...
Proceedings of the National Academy of Sciences 111 (50), E5383-E5392, 2014
Pacemaker current (If) in the human sinoatrial node
AO Verkerk, R Wilders, MMGJ van Borren, RJG Peters, E Broekhuis, ...
European heart journal 28 (20), 2472-2478, 2007
RBM20 mutations induce an arrhythmogenic dilated cardiomyopathy related to disturbed calcium handling
MMG van den Hoogenhof, A Beqqali, AS Amin, I van der Made, S Aufiero, ...
Circulation 138 (13), 1330-1342, 2018
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells
ML Bakker, GJJ Boink, BJ Boukens, AO Verkerk, M Van Den Boogaard, ...
Cardiovascular research 94 (3), 439-449, 2012
Functional NaV1.8 Channels in Intracardiac Neurons: The Link Between SCN10A and Cardiac Electrophysiology
AO Verkerk, CA Remme, CA Schumacher, BP Scicluna, R Wolswinkel, ...
Circulation research 111 (3), 333-343, 2012
Pro-and antiarrhythmic properties of a diet rich in fish oil
HM Den Ruijter, G Berecki, T Opthof, AO Verkerk, PL Zock, R Coronel
Cardiovascular research 73 (2), 316-325, 2007
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