A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis H Choi, S Tessier, ES Silagi, R Kyada, F Yousefi, N Pleshko, IM Shapiro, ... Matrix Biology 70, 102-122, 2018 | 116 | 2018 |
Glycosaminoglycan synthesis in the nucleus pulposus: dysregulation and the pathogenesis of disc degeneration ES Silagi, IM Shapiro, MV Risbud Matrix Biology 71, 368-379, 2018 | 112 | 2018 |
Hypoxic regulation of mitochondrial metabolism and mitophagy in nucleus pulposus cells is dependent on HIF‐1α–BNIP3 axis V Madhu, PK Boneski, E Silagi, Y Qiu, I Kurland, AR Guntur, IM Shapiro, ... Journal of Bone and Mineral Research 35 (8), 1504-1524, 2020 | 84 | 2020 |
Bicarbonate recycling by HIF‐1–dependent carbonic anhydrase isoforms 9 and 12 is critical in maintaining intracellular pH and viability of nucleus pulposus cells ES Silagi, ZR Schoepflin, EL Seifert, C Merceron, E Schipani, IM Shapiro, ... Journal of bone and Mineral Research 33 (2), 338-355, 2018 | 57 | 2018 |
Lactate efflux from intervertebral disc cells is required for maintenance of spine health ES Silagi, EJ Novais, S Bisetto, AG Telonis, J Snuggs, CL Le Maitre, Y Qiu, ... Journal of Bone and Mineral Research 35 (3), 550-570, 2020 | 56 | 2020 |
The role of HIF proteins in maintaining the metabolic health of the intervertebral disc ES Silagi, E Schipani, IM Shapiro, MV Risbud Nature Reviews Rheumatology 17 (7), 426-439, 2021 | 53 | 2021 |
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival Y Fukuda, MF Pazyra-Murphy, ES Silagi, OE Tasdemir-Yilmaz, Y Li, ... Journal of Cell Biology 220 (1), e202005051, 2020 | 49 | 2020 |
Expression of carbonic anhydrase III, a nucleus pulposus phenotypic marker, is hypoxia-responsive and confers protection from oxidative stress-induced cell death ES Silagi, P Batista, IM Shapiro, MV Risbud Scientific Reports 8 (1), 4856, 2018 | 41 | 2018 |
Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health K Suyama, ES Silagi, H Choi, K Sakabe, J Mochida, IM Shapiro, ... Oncotarget 7 (17), 23056, 2016 | 41 | 2016 |
PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis ZR Schoepflin, ES Silagi, IM Shapiro, MV Risbud The FASEB Journal 31 (9), 3831, 2017 | 26 | 2017 |
GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc SN Johnston, ES Silagi, V Madhu, DH Nguyen, IM Shapiro, MV Risbud JCI insight 8 (8), 2023 | 6 | 2023 |
Uncomfortably numb: how Nav1.7 mediates paclitaxel-induced peripheral neuropathy ES Silagi, RA Segal Brain 144 (6), 1621-1623, 2021 | 3 | 2021 |
Hypoxia and HIFs maintain the metabolic health of cells of the intervertebral disc ES Silagi, E Schipani, IM Shapiro, MV Risbud Nature reviews. Rheumatology 17 (7), 426, 2021 | 1 | 2021 |
Insights into Glycolytic Metabolism and pH Homeostasis in the Hypoxic Intervertebral Disc ES Silagi Thomas Jefferson University, 2019 | | 2019 |