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Kathryn E. Wellen
Kathryn E. Wellen
Geverifieerd e-mailadres voor upenn.edu
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Inflammation, stress, and diabetes
KE Wellen, GS Hotamisligil
The Journal of clinical investigation 115 (5), 1111-1119, 2005
56552005
Obesity-induced inflammatory changes in adipose tissue
KE Wellen, GS Hotamisligil
The Journal of clinical investigation 112 (12), 1785-1788, 2003
24662003
ATP-citrate lyase links cellular metabolism to histone acetylation
KE Wellen, G Hatzivassiliou, UM Sachdeva, TV Bui, JR Cross, ...
Science 324 (5930), 1076-1080, 2009
21752009
IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
21362012
Cellular metabolic stress: considering how cells respond to nutrient excess
KE Wellen, CB Thompson
Molecular cell 40 (2), 323-332, 2010
5482010
A two-way street: reciprocal regulation of metabolism and signalling
KE Wellen, CB Thompson
Nature reviews Molecular cell biology 13 (4), 270-276, 2012
5412012
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation
JV Lee, A Carrer, S Shah, NW Snyder, S Wei, S Venneti, AJ Worth, ...
Cell metabolism 20 (2), 306-319, 2014
5372014
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence
P Jiang, W Du, A Mancuso, KE Wellen, X Yang
Nature 493 (7434), 689-693, 2013
4882013
Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis
D Daye, KE Wellen
Seminars in cell & developmental biology 23 (4), 362-369, 2012
4362012
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
KE Wellen, C Lu, A Mancuso, JMS Lemons, M Ryczko, JW Dennis, ...
Genes & development 24 (24), 2784-2799, 2010
4352010
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
OG McDonald, X Li, T Saunders, R Tryggvadottir, SJ Mentch, ...
Nature genetics 49 (3), 367-376, 2017
4172017
Metabolic control of epigenetics in cancer
A Kinnaird, S Zhao, KE Wellen, ED Michelakis
Nature Reviews Cancer 16 (11), 694-707, 2016
3952016
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ...
Nature 579 (7800), 586-591, 2020
3582020
ATP-citrate lyase controls a glucose-to-acetate metabolic switch
S Zhao, AM Torres, RA Henry, S Trefely, M Wallace, JV Lee, A Carrer, ...
Cell reports 17 (4), 1037-1052, 2016
3422016
Designing a broad-spectrum integrative approach for cancer prevention and treatment
KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ...
Seminars in cancer biology 35, S276-S304, 2015
3032015
Designing a broad-spectrum integrative approach for cancer prevention and treatment
KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ...
Seminars in cancer biology 35, S276-S304, 2015
3032015
Dysregulated metabolism contributes to oncogenesis
MD Hirschey, RJ DeBerardinis, AME Diehl, JE Drew, C Frezza, MF Green, ...
Seminars in cancer biology 35, S129-S150, 2015
3012015
Acetate production from glucose and coupling to mitochondrial metabolism in mammals
X Liu, DE Cooper, AA Cluntun, MO Warmoes, S Zhao, MA Reid, J Liu, ...
Cell 175 (2), 502-513. e13, 2018
2962018
Metabolic control of methylation and acetylation
X Su, KE Wellen, JD Rabinowitz
Current opinion in chemical biology 30, 52-60, 2016
2712016
Spatiotemporal control of acetyl-CoA metabolism in chromatin regulation
S Sivanand, I Viney, KE Wellen
Trends in biochemical sciences 43 (1), 61-74, 2018
2612018
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Artikelen 1–20