Polyfluorinated groups in medicinal chemistry M Bassetto, S Ferla, F Pertusati Future Medicinal Chemistry 7 (4), 527-546, 2015 | 109 | 2015 |
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous … A Płaszczyca, P Scaturro, CJ Neufeldt, M Cortese, B Cerikan, S Ferla, ... PLoS Pathogens 15 (5), e1007736, 2019 | 81 | 2019 |
Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization F Grande, OI Parisi, RA Mordocco, C Rocca, F Puoci, L Scrivano, ... European Journal of Pharmaceutical Sciences 82, 161-170, 2016 | 73 | 2016 |
Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer M Bassetto, S Ferla, F Pertusati, S Kandil, AD Westwell, A Brancale, ... European Journal of Medicinal Chemistry 118, 230-243, 2016 | 70 | 2016 |
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis SN Lauder, K Allen-Redpath, DA Slatter, M Aldrovandi, A O’Connor, ... Science signaling 10 (507), eaan2787, 2017 | 49 | 2017 |
Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication M Scuotto, R Abdelnabi, S Collarile, C Schiraldi, L Delang, A Massa, ... Bioorganic & medicinal chemistry 25 (1), 327-337, 2017 | 46 | 2017 |
Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni G Padalino, S Ferla, A Brancale, IW Chalmers, KF Hoffmann International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 559-570, 2018 | 42 | 2018 |
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and … R Romagnoli, F Prencipe, P Oliva, S Baraldi, PG Baraldi, ... Journal of Medicinal Chemistry 62 (3), 1274-1290, 2019 | 39 | 2019 |
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole R Romagnoli, PG Baraldi, F Prencipe, P Oliva, S Baraldi, MA Tabrizi, ... Scientific reports 6 (1), 26602, 2016 | 37 | 2016 |
Suramin inhibits chikungunya virus replication by interacting with virions and blocking the early steps of infection IC Albulescu, L White-Scholten, A Tas, TE Hoornweg, S Ferla, ... Viruses 12 (3), 314, 2020 | 30 | 2020 |
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets KCL Whatley, G Padalino, H Whiteland, KK Geyer, BJ Hulme, ... PLoS Neglected Tropical Diseases 13 (11), e0007693, 2019 | 30 | 2019 |
In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase S Ferla, NE Netzler, S Ferla, S Veronese, DE Tuipulotu, S Guccione, ... Scientific reports 8 (1), 4129, 2018 | 30 | 2018 |
Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP) L Bauer, S Ferla, SA Head, S Bhat, KK Pasunooti, WQ Shi, L Albulescu, ... Antiviral Research 156, 55-63, 2018 | 27 | 2018 |
Therapeutically targeting guanylate cyclase‐C: computational modeling of plecanatide, a uroguanylin analog A Brancale, K Shailubhai, S Ferla, A Ricci, M Bassetto, GS Jacob Pharmacology Research & Perspectives 5 (2), e00295, 2017 | 27 | 2017 |
Successful subthalamic stimulation in genetic Parkinson’s disease caused by duplication of the α-synuclein gene A Antonini, M Pilleri, A Padoan, A Landi, S Ferla, R Biundo, D D’Avella Journal of neurology 259, 165-167, 2012 | 27 | 2012 |
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo [b] furan derivatives as highly potent tubulin polymerization inhibitors P Oliva, R Romagnoli, S Manfredini, A Brancale, S Ferla, E Hamel, ... European Journal of Medicinal Chemistry 200, 112448, 2020 | 26 | 2020 |
Broad-spectrum non-nucleoside inhibitors for caliciviruses NE Netzler, DE Tuipulotu, AA Eltahla, JH Lun, S Ferla, A Brancale, ... Antiviral research 146, 65-75, 2017 | 26 | 2017 |
Targeting the complement serine protease MASP-2 as a therapeutic strategy for coronavirus infections BM Flude, G Nannetti, P Mitchell, N Compton, C Richards, M Heurich, ... Viruses 13 (2), 312, 2021 | 24 | 2021 |
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C L Bauer, R Manganaro, B Zonsics, DL Hurdiss, M Zwaagstra, T Donselaar, ... PLoS Biology 18 (11), e3000904, 2020 | 24 | 2020 |
Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors R Manganaro, B Zonsics, L Bauer, ML Lopez, T Donselaar, M Zwaagstra, ... Antiviral Research 178, 104781, 2020 | 24 | 2020 |