Endothelial activation and blood–brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells J Gust, KA Hay, LA Hanafi, D Li, D Myerson, LF Gonzalez-Cuyar, C Yeung, ... Cancer discovery 7 (12), 1404-1419, 2017 | 1172 | 2017 |
Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy KA Hay, LA Hanafi, D Li, J Gust, WC Liles, MM Wurfel, JA López, J Chen, ... Blood, The Journal of the American Society of Hematology 130 (21), 2295-2306, 2017 | 956 | 2017 |
Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice DA Lamba, J Gust, TA Reh Cell stem cell 4 (1), 73-79, 2009 | 722 | 2009 |
Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy RA Gardner, F Ceppi, J Rivers, C Annesley, C Summers, A Taraseviciute, ... Blood, The Journal of the American Society of Hematology 134 (24), 2149-2158, 2019 | 242 | 2019 |
Neurotoxicity associated with CD19-targeted CAR-T cell therapies J Gust, A Taraseviciute, CJ Turtle CNS drugs 32, 1091-1101, 2018 | 228 | 2018 |
Spontaneous, synchronous electrical activity in neonatal mouse cortical neurones R Corlew, MM Bosma, WJ Moody The Journal of physiology 560 (2), 377-390, 2004 | 173 | 2004 |
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis NA Vitanza, AJ Johnson, AL Wilson, C Brown, JK Yokoyama, A Künkele, ... Nature medicine 27 (9), 1544-1552, 2021 | 167 | 2021 |
Cytokines in CAR T cell–associated neurotoxicity J Gust, R Ponce, WC Liles, GA Garden, CJ Turtle Frontiers in Immunology 11, 577027, 2020 | 144 | 2020 |
Glial injury in neurotoxicity after pediatric CD19‐directed chimeric antigen receptor T cell therapy J Gust, OC Finney, D Li, HM Brakke, RM Hicks, RB Futrell, DN Gamble, ... Annals of neurology 86 (1), 42-54, 2019 | 144 | 2019 |
Adult donor rod photoreceptors integrate into the mature mouse retina J Gust, TA Reh Investigative ophthalmology & visual science 52 (8), 5266-5272, 2011 | 108 | 2011 |
Intraventricular B7-H3 CAR T cells for diffuse intrinsic pontine glioma: preliminary first-in-human bioactivity and safety NA Vitanza, AL Wilson, W Huang, K Seidel, C Brown, JA Gustafson, ... Cancer discovery 13 (1), 114-131, 2023 | 93 | 2023 |
Development of synchronized activity of cranial motor neurons in the segmented embryonic mouse hindbrain J Gust, JJ Wright, EB Pratt, MM Bosma The Journal of physiology 550 (1), 123-133, 2003 | 67 | 2003 |
Decreased rates of severe CRS seen with early intervention strategies for CD19 CAR-T cell toxicity management R Gardner, KJ Leger, CE Annesley, C Summers, J Rivers, J Gust, ... Blood 128 (22), 586, 2016 | 63 | 2016 |
EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma AC Ravanpay, J Gust, AJ Johnson, LS Rolczynski, M Cecchini, CA Chang, ... Oncotarget 10 (66), 7080, 2019 | 60 | 2019 |
Beyond the storm—subacute toxicities and late effects in children receiving CAR T cells H Shalabi, J Gust, A Taraseviciute, PL Wolters, AB Leahy, C Sandi, ... Nature Reviews Clinical Oncology 18 (6), 363-378, 2021 | 44 | 2021 |
Directing human embryonic stem cells to a retinal fate. TA Reh, D Lamba, J Gust Methods In Molecular Biology Clifton Nj 636, 115-128, 2006 | 41* | 2006 |
Tumor inflammation-associated neurotoxicity J Mahdi, J Dietrich, K Straathof, C Roddie, BJ Scott, TB Davidson, ... Nature medicine 29 (4), 803-810, 2023 | 26 | 2023 |
Characterization of a severe case of PIK3CA‐related overgrowth at autopsy by droplet digital polymerase chain reaction and report of PIK3CA sequencing in 22 … AM Piacitelli, DM Jensen, H Brandling‐Bennett, MM Gray, M Batra, J Gust, ... American Journal of Medical Genetics Part A 176 (11), 2301-2308, 2018 | 22 | 2018 |
EEG correlates of delirium in children and young adults with CD19-directed CAR T cell treatment-related neurotoxicity J Gust, CE Annesley, RA Gardner, X Bozarth Journal of Clinical Neurophysiology 38 (2), 135-142, 2021 | 21 | 2021 |
Cytokine release syndrome (CRS) and neurotoxicity (NT) after CD19-specific chimeric antigen receptor-(CAR-) modified T cells. CJ Turtle, KA Hay, J Gust, LA Hanafi, D Li, WC Liles, M Wurfel, ... Journal of Clinical Oncology 35 (15_suppl), 3020-3020, 2017 | 21 | 2017 |