| Structural insights into the mechanism and inhibition of eukaryotic O‐GlcNAc hydrolysis FV Rao, HC Dorfmueller, F Villa, M Allwood, IM Eggleston, ... The EMBO journal 25 (7), 1569-1578, 2006 | 251 | 2006 |
| Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction S Santaguida, C Vernieri, F Villa, A Ciliberto, A Musacchio The EMBO journal 30 (8), 1508-1519, 2011 | 239 | 2011 |
| Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells AM D'Alise, G Amabile, M Iovino, FP Di Giorgio, M Bartiromo, F Sessa, ... Molecular cancer therapeutics 7 (5), 1140-1149, 2008 | 150 | 2008 |
| The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation M Jaleel, F Villa, M Deak, R Toth, AR Prescott, DMF van Aalten, DR Alessi Biochemical Journal 394 (3), 545-555, 2006 | 139 | 2006 |
| Molecular basis of drug resistance in aurora kinases F Girdler, F Sessa, S Patercoli, F Villa, A Musacchio, S Taylor Chemistry & biology 15 (6), 552-562, 2008 | 134 | 2008 |
| Ctf4 is a hub in the eukaryotic replisome that links multiple CIP-box proteins to the CMG helicase F Villa, AC Simon, MAO Bazan, ML Kilkenny, D Wirthensohn, M Wightman, ... Molecular Cell, 2016 | 126 | 2016 |
| Differential redox regulation within the PTP superfamily SH Ross, Y Lindsay, ST Safrany, O Lorenzo, F Villa, R Toth, MJ Clague, ... Cellular signalling 19 (7), 1521-1530, 2007 | 116 | 2007 |
| Drf1, a novel regulatory subunit for human Cdc7 kinase A Montagnoli, R Bosotti, F Villa, M Rialland, D Brotherton, C Mercurio, ... The EMBO journal 21 (12), 3171-3181, 2002 | 106 | 2002 |
| Structural insights into the recognition of substrates and activators by the OSR1 kinase F Villa, J Goebel, FH Rafiqi, M Deak, J Thastrup, DR Alessi, ... EMBO reports 8 (9), 839-845, 2007 | 93 | 2007 |
| Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization F Villa, P Capasso, M Tortorici, F Forneris, A de Marco, A Mattevi, ... Proceedings of the National Academy of Sciences 106 (48), 20204-20209, 2009 | 69 | 2009 |
| A general framework for inhibitor resistance in protein kinases D Balzano, S Santaguida, A Musacchio, F Villa Chemistry & biology 18 (8), 966-975, 2011 | 67 | 2011 |
| Discovery of selective aminothiazole aurora kinase inhibitors CB Andersen, Y Wan, JW Chang, B Riggs, C Lee, Y Liu, F Sessa, F Villa, ... ACS chemical biology 3 (3), 180-192, 2008 | 56 | 2008 |
| Modulation of the chromatin phosphoproteome by the Haspin protein kinase A Maiolica, M de Medina-Redondo, EM Schoof, A Chaikuad, F Villa, ... Molecular & Cellular Proteomics 13 (7), 1724-1740, 2014 | 51 | 2014 |
| Crystal Structure of the PTPL1/FAP-1 Human Tyrosine Phosphatase Mutated in Colorectal Cancer EVIDENCE FOR A SECOND PHOSPHOTYROSINE SUBSTRATE RECOGNITION POCKET F Villa, M Deak, GB Bloomberg, DR Alessi, DMF van Aalten Journal of Biological Chemistry 280 (9), 8180-8187, 2005 | 49 | 2005 |
| Structure of the OSR1 kinase, a hypertension drug target F Villa, M Deak, DR Alessi, DMF Van Aalten Proteins: Structure, Function, and Bioinformatics 73 (4), 1082-1087, 2008 | 44 | 2008 |
| Structure of Aurora B–INCENP in complex with barasertib reveals a potential transinhibitory mechanism F Sessa, F Villa Acta Crystallographica Section F: Structural Biology Communications 70 (3 …, 2014 | 40 | 2014 |
| Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen N Kwiatkowski, X Deng, J Wang, L Tan, F Villa, S Santaguida, HC Huang, ... ACS chemical biology 7 (1), 185-196, 2011 | 35 | 2011 |
| Targeting the Genome‐Stability Hub Ctf4 by Stapled‐Peptide Design Y Wu, F Villa, J Maman, YH Lau, L Dobnikar, AC Simon, K Labib, ... Angewandte Chemie 129 (42), 13046-13052, 2017 | 29 | 2017 |
| CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle F Villa, R Fujisawa, J Ainsworth, K Nishimura, M Lie‐A‐Ling, G Lacaud, ... EMBO reports, e52164, 0 | 27 | |
