A luminal epithelial stem cell that is a cell of origin for prostate cancer XI Wang, MK Julio, KD Economides, D Walker, H Yu, MV Halili, YP Hu, ... Nature 461 (7263), 495-500, 2009 | 875 | 2009 |
Nkx3. 1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases C Abate-Shen, WA Banach-Petrosky, X Sun, KD Economides, N Desai, ... Cancer research 63 (14), 3886-3890, 2003 | 297 | 2003 |
Hoxb13 is required for normal differentiation and secretory function of the ventral prostate KD Economides, MR Capecchi Oxford University Press for The Company of Biologists Limited 130 (10), 2061 …, 2003 | 192 | 2003 |
Hoxb13 mutations cause overgrowth of caudal spinal cordand tail vertebrae KD Economides, L Zeltser, MR Capecchi Developmental biology 256 (2), 317-330, 2003 | 179 | 2003 |
A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties K Dooley, RE McConnell, K Xu, ND Lewis, S Haupt, MR Youniss, S Martin, ... Molecular Therapy 29 (5), 1729-1743, 2021 | 173 | 2021 |
PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein H Lee, JC Quinn, KV Prasanth, VA Swiss, KD Economides, MM Camacho, ... Genes & development 20 (7), 784-794, 2006 | 117 | 2006 |
Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity S Kamerkar, C Leng, O Burenkova, SC Jang, C McCoy, K Zhang, ... Science advances 8 (7), eabj7002, 2022 | 116 | 2022 |
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance SC Jang, KD Economides, RJ Moniz, CL Sia, N Lewis, C McCoy, T Zi, ... Communications biology 4 (1), 497, 2021 | 90 | 2021 |
Exosome surface display of IL12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared with recombinant IL12 ND Lewis, CL Sia, K Kirwin, S Haupt, G Mahimkar, T Zi, K Xu, K Dooley, ... Molecular cancer therapeutics 20 (3), 523-534, 2021 | 58 | 2021 |
Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility CR Vianna, J Donato, J Rossi, M Scott, K Economides, L Gautron, ... Journal of Neuroscience 32 (30), 10331-10337, 2012 | 56 | 2012 |
The Central Cannabinoid CB1 Receptor Is Required for Diet‐Induced Obesity and Rimonabant's Antiobesity Effects in Mice Z Pang, NN Wu, W Zhao, DC Chain, E Schaffer, X Zhang, P Yamdagni, ... Obesity 19 (10), 1923-1934, 2011 | 39 | 2011 |
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs MR Golder, J Liu, JN Andersen, MV Shipitsin, F Vohidov, HVT Nguyen, ... Nature biomedical engineering 2 (11), 822-830, 2018 | 33 | 2018 |
Design of BET inhibitor bottlebrush prodrugs with superior efficacy and devoid of systemic toxicities F Vohidov, JN Andersen, KD Economides, MV Shipitsin, O Burenkova, ... Journal of the American Chemical Society 143 (12), 4714-4724, 2021 | 25 | 2021 |
Progenitor cells for the prostate epithelium: roles in development, regeneration, and cancer MM Shen, X Wang, KD Economides, D Walker, C Abate-Shen Cold Spring Harbor Symposia on Quantitative Biology 73, 529-538, 2008 | 25 | 2008 |
DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness ELV Malavasi, KD Economides, E Grünewald, P Makedonopoulou, ... Translational psychiatry 8 (1), 184, 2018 | 21 | 2018 |
Familial t (1; 11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte–myelin dysfunction NA Vasistha, M Johnstone, SK Barton, SE Mayerl, B Thangaraj Selvaraj, ... Molecular psychiatry 24 (11), 1641-1654, 2019 | 17 | 2019 |
In vivo tracking of [89Zr] Zr-labeled engineered extracellular vesicles by PET reveals organ-specific biodistribution based upon the route of administration S Patel, KF Schmidt, M Farhoud, T Zi, SC Jang, K Dooley, D Kentala, ... Nuclear medicine and biology 112, 20-30, 2022 | 16 | 2022 |
exoSTING: An engineered exosome therapeutic that selectively delivers STING agonist to the tumor resident antigen-presenting cells resulting in improved tumor antigen-specific … SC Jang, RJ Moniz, CL Sia, RA Harrison, D Houde, N Ross, K Xu, ... Cancer Research 79 (13_Supplement), 944-944, 2019 | 13 | 2019 |
The CRE luc bioluminescence transgenic mouse model for detecting ligand activation of GPCRs H Dressler, K Economides, S Favara, NN Wu, Z Pang, HG Polites Journal of biomolecular screening 19 (2), 232-241, 2014 | 12 | 2014 |
LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation [S] C Pipper, N Bordag, B Reiter, K Economides, P Florian, T Birngruber, ... Journal of Lipid Research 60 (4), 758-766, 2019 | 11 | 2019 |