Christoph Jan Wruck
Christoph Jan Wruck
Dozent Anatomie RWTH Aachen
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Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice
CJ Wruck, A Fragoulis, A Gurzynski, LO Brandenburg, YW Kan, K Chan, ...
Annals of the rheumatic diseases 70 (5), 844-850, 2011
Luteolin protects rat PC 12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keapl-Nrf2-ARE pathway
CJ Wruck, M Claussen, G Fuhrmann, L Römer, A Schulz, T Pufe, ...
Neuropsychiatric disorders an integrative approach, 57-67, 2007
Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis
Z Fan, AK Wirth, D Chen, CJ Wruck, M Rauh, M Buchfelder, N Savaskan
Oncogenesis 6 (8), e371-e371, 2017
Regulation of transport of the angiotensin AT2 receptor by a novel membrane-associated Golgi protein
CJ Wruck, H Funke-Kaiser, T Pufe, H Kusserow, M Menk, JH Schefe, ...
Arteriosclerosis, thrombosis, and vascular biology 25 (1), 57-64, 2005
Sulforaphane suppresses LPS-induced inflammation in primary rat microglia
LO Brandenburg, M Kipp, R Lucius, T Pufe, CJ Wruck
Inflammation Research 59 (6), 443-450, 2010
Kavalactones protect neural cells against amyloid β peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related …
CJ Wruck, ME Götz, T Herdegen, D Varoga, LO Brandenburg, T Pufe
Molecular pharmacology 73 (6), 1785-1795, 2008
Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter
CJ Wruck, K Streetz, G Pavic, ME Götz, M Tohidnezhad, LO Brandenburg, ...
Journal of Biological Chemistry 286 (6), 4493-4499, 2011
Intraarticular injection of platelet‐rich plasma reduces inflammation in a pig model of rheumatoid arthritis of the knee joint
S Lippross, B Moeller, H Haas, M Tohidnezhad, N Steubesand, CJ Wruck, ...
Arthritis & rheumatism 63 (11), 3344-3353, 2011
Nrf2 in health and disease: current and future clinical implications
O Al-Sawaf, T Clarner, A Fragoulis, YW Kan, T Pufe, K Streetz, CJ Wruck
Clinical science 129 (12), 989-999, 2015
Platelet-released growth factors can accelerate tenocyte proliferation and activate the anti-oxidant response element
M Tohidnezhad, D Varoga, CJ Wruck, LO Brandenburg, A Seekamp, ...
Histochemistry and cell biology 135 (5), 453-460, 2011
LuSens: a keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification
T Ramirez, A Mehling, SN Kolle, CJ Wruck, W Teubner, T Eltze, ...
Toxicology in Vitro 28 (8), 1482-1497, 2014
Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia
N Kweider, A Fragoulis, C Rosen, U Pecks, W Rath, T Pufe, CJ Wruck
Journal of Biological Chemistry 286 (50), 42863-42872, 2011
Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants
J Fay, D Varoga, CJ Wruck, B Kurz, MB Goldring, T Pufe
Arthritis research & therapy 8 (6), 1-8, 2006
Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals
C Bauch, SN Kolle, E Fabian, C Pachel, T Ramirez, B Wiench, CJ Wruck, ...
Toxicology in Vitro 25 (6), 1162-1168, 2011
Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)-and amyloid beta 1-42-induced signal transduction in glial cells
A Slowik, J Merres, A Elfgen, S Jansen, F Mohr, CJ Wruck, T Pufe, ...
Molecular neurodegeneration 7 (1), 1-18, 2012
Local treatment of meniscal lesions with vascular endothelial growth factor
S Kopf, F Birkenfeld, R Becker, W Petersen, C Stärke, CJ Wruck, ...
JBJS 92 (16), 2682-2691, 2010
Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis
LO Brandenburg, D Varoga, N Nicolaeva, SL Leib, H Wilms, R Podschun, ...
Journal of Neuropathology & Experimental Neurology 67 (11), 1041-1054, 2008
Platelets display potent antimicrobial activity and release human beta-defensin 2
M Tohidnezhad, D Varoga, CJ Wruck, R Podschun, BH Sachweh, ...
Platelets 23 (3), 217-223, 2012
Functional and physical interactions between formyl‐peptide‐receptors and scavenger receptor MARCO and their involvement in amyloid beta 1–42‐induced signal transduction in …
LO Brandenburg, M Konrad, CJ Wruck, T Koch, R Lucius, T Pufe
Journal of neurochemistry 113 (3), 749-760, 2010
Role of platelet-released growth factors in detoxification of reactive oxygen species in osteoblasts
M Tohidnezhad, CJ Wruck, A Slowik, N Kweider, R Beckmann, A Bayer, ...
Bone 65, 9-17, 2014
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