Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates JE Dunford, K Thompson, FP Coxon, SP Luckman, FM Hahn, CD Poulter, ... Journal of Pharmacology and Experimental Therapeutics 296 (2), 235-242, 2001 | 1209 | 2001 |
Molecular mechanisms of action of bisphosphonates: current status AJ Roelofs, K Thompson, S Gordon, MJ Rogers Clinical Cancer Research 12 (20), 6222s-6230s, 2006 | 734 | 2006 |
Recent advances in understanding the mechanism of action of bisphosphonates FP Coxon, K Thompson, MJ Rogers Current opinion in pharmacology 6 (3), 307-312, 2006 | 351 | 2006 |
Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP AJ Roelofs, M Jauhiainen, H Mönkkönen, MJ Rogers, J Mönkkönen, ... British journal of haematology 144 (2), 245-250, 2009 | 327 | 2009 |
Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis K Thompson, MJ Rogers, FP Coxon, JC Crockett Molecular pharmacology 69 (5), 1624-1632, 2006 | 299 | 2006 |
Statins prevent bisphosphonate‐induced γ, δ‐T‐cell proliferation and activation in vitro K Thompson, MJ Rogers Journal of Bone and Mineral Research 19 (2), 278-288, 2004 | 293 | 2004 |
Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells FP Coxon, K Thompson, AJ Roelofs, FH Ebetino, MJ Rogers Bone 42 (5), 848-860, 2008 | 287 | 2008 |
Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages A J Roelofs, K Thompson, F H Ebetino, M J Rogers, F P Coxon Current pharmaceutical design 16 (27), 2950-2960, 2010 | 238 | 2010 |
Pathogenic Mechanisms and Host Interactions in Staphylococcus epidermidis Device-Related Infection M Sabaté Brescó, LG Harris, K Thompson, B Stanic, M Morgenstern, ... Frontiers in microbiology 8, 1401, 2017 | 218 | 2017 |
Functional biomaterials for bone regeneration: a lesson in complex biology AR Armiento, LP Hatt, G Sanchez Rosenberg, K Thompson, MJ Stoddart Advanced Functional Materials 30 (44), 1909874, 2020 | 157 | 2020 |
Alkylamines cause Vγ9Vδ2 T-cell activation and proliferation by inhibiting the mevalonate pathway K Thompson, J Rojas-Navea, MJ Rogers Blood 107 (2), 651-654, 2006 | 129 | 2006 |
A global benchmark study using affinity-based biosensors RL Rich, GA Papalia, PJ Flynn, J Furneisen, J Quinn, JS Klein, ... Analytical biochemistry 386 (2), 194-216, 2009 | 124 | 2009 |
IL-23 inhibits osteoclastogenesis indirectly through lymphocytes and is required for the maintenance of bone mass in mice JMW Quinn, NA Sims, H Saleh, D Mirosa, K Thompson, S Bouralexis, ... The Journal of Immunology 181 (8), 5720-5729, 2008 | 103 | 2008 |
Current concepts of osteomyelitis: from pathological mechanisms to advanced research methods. MI Hofstee, G Muthukrishnan, GJ Atkins, M Riool, K Thompson, ... The American Journal of Pathology 190 (6), 1151-1163, 2020 | 91 | 2020 |
Activation of γδ T cells by bisphosphonates K Thompson, AJ Roelofs, M Jauhiainen, H Mönkkönen, J Mönkkönen, ... Osteoimmunology: Interactions of the Immune and skeletal systems II, 11-20, 2010 | 91 | 2010 |
Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase K Thompson, JE Dunford, FH Ebetino, MJ Rogers Biochemical and biophysical research communications 290 (2), 869-873, 2002 | 74 | 2002 |
The effect of krill oil supplementation on exercise performance and markers of immune function M Da Boit, I Mastalurova, G Brazaite, N McGovern, K Thompson, SR Gray Plos one 10 (9), e0139174, 2015 | 38 | 2015 |
Fluvastatin does not prevent the acute-phase response to intravenous zoledronic acid in post-menopausal women K Thompson, F Keech, DJ McLernon, K Vinod, RJ May, WG Simpson, ... Bone 49 (1), 140-145, 2011 | 35 | 2011 |
Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro A Pappalardo, K Thompson Clinical & Experimental Immunology 174 (2), 281-291, 2013 | 34 | 2013 |
Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections SG Rotman, K Thompson, DW Grijpma, RG Richards, TF Moriarty, D Eglin, ... Journal of orthopaedic translation 21, 136-145, 2020 | 32 | 2020 |