| Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy I Karakikes, F Stillitano, M Nonnenmacher, C Tzimas, D Sanoudou, ... Nature communications 6 (1), 6955, 2015 | 200 | 2015 |
| Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-κB C Tzimas, G Michailidou, M Arsenakis, E Kieff, G Mosialos, ... Cellular signalling 18 (1), 83-92, 2006 | 90 | 2006 |
| Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway SI Bibli, I Andreadou, A Chatzianastasiou, C Tzimas, D Sanoudou, ... Cardiovascular research 106 (3), 432-442, 2015 | 80 | 2015 |
| Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor S Bhattacharya, J Qian, C Tzimas, DP Baker, C Koumenis, JA Diehl, ... Journal of Biological Chemistry 286 (25), 22069-22076, 2011 | 57 | 2011 |
| Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFNα via accelerating the degradation of its receptor S Bhattacharya, H Zheng, C Tzimas, M Carroll, DP Baker, SY Fuchs Blood, The Journal of the American Society of Hematology 118 (15), 4179-4187, 2011 | 44 | 2011 |
| Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation B Varghese, G Swaminathan, A Plotnikov, C Tzimas, N Yang, H Rui, ... Molecular endocrinology 24 (12), 2356-2365, 2010 | 33 | 2010 |
| Clinico-histopathologic and single-nuclei RNA-sequencing insights into cardiac injury and microthrombi in critical COVID-19 MI Brener, ML Hulke, N Fukuma, S Golob, RS Zilinyi, Z Zhou, C Tzimas, ... JCI insight 7 (2), 2022 | 23 | 2022 |
| WIPI1 is a conserved mediator of right ventricular failure C Tzimas, CD Rau, PE Buergisser, G Jean-Louis Jr, K Lee, ... JCI insight 4 (11), 2019 | 19 | 2019 |
| Notch represses transcription by PRC2 recruitment to the ternary complex X Han, P Ranganathan, C Tzimas, KL Weaver, K Jin, L Astudillo, W Zhou, ... Molecular Cancer Research 15 (9), 1173-1183, 2017 | 17 | 2017 |
| Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant C Tzimas, DM Johnson, DJ Santiago, E Vafiadaki, DA Arvanitis, ... Cardiovascular Research 113 (11), 1403-1417, 2017 | 16 | 2017 |
| The expanding role of epigenetics G Kalozoumi, C Tzimas, D Sanoudou Global Cardiology Science and Practice 2012 (1), 7, 2012 | 13 | 2012 |
| Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions C Tzimas, J Terrovitis, SE Lehnart, EG Kranias, D Sanoudou Heart Rhythm 12 (7), 1599-1610, 2015 | 12 | 2015 |
| Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Nat Commun. 2015; 6: 6955 I Karakikes, F Stillitano, M Nonnenmacher, C Tzimas, D Sanoudou, ... This proof-of-principle study describes how engineered nucleases can be used …, 2016 | 6 | 2016 |
| Molecular Pathophysiology of Cardiac Injury and Cardiac Microthrombi in Fatal COVID-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing Analyses N Fukuma, ML Hulke, MI Brener, S Golob, R Zilinyi, Z Zhou, C Tzimas, ... BioRxiv, 2021.07. 27.453843, 2021 | 1 | 2021 |
| CaMKII inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions C Tzimas, J Terrovitis, SE Lehnart, EG Kranias, D Sanoudou Heart rhythm: the official journal of the Heart Rhythm Society 12 (7), 1599, 2015 | 1 | 2015 |
| A novel role for phospholamban in the thalamic reticular nucleus B Klocke, A Britzolaki, J Saurine, H Ott, K Krone, K Bahamonde, C Thelen, ... Scientific Reports 14 (1), 6376, 2024 | | 2024 |
| Extracellular Matrix Instability and Chronic Inflammation Underlie Maladaptive Right Ventricular Pressure Overload Remodeling and Failure in Male Mice I Russo, W Dun, S Mehta, S Amed, C Tzimas, N Fukuma, EJ Tsai bioRxiv, 2024.04. 03.588013, 2024 | | 2024 |
| Atrial Fibrillation and Atrial Remodeling Deteriorates Right Heart Function With Preserved LV Function in LKB1f/f/ANFCre+ Mice N Fukuma, C Tzimas, I Russo, W Dun, EJ Tsai Circulation 148 (Suppl_1), A12370-A12370, 2023 | | 2023 |
| Molecular Pathogenesis of Cardiac Microthrombi in Fatal Covid-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing Analyses NJ Fukuma, M Brener, M Hulke, N Fukuma, S Golob, R Zilinyi, Z Zhou, ... Circulation 144 (Suppl_1), A14422-A14422, 2021 | | 2021 |
| Sex Differences in GC1-cGMP Related Cardioprotective Mechanism for Right Heart Failure in Mice Subjected to Right Ventricular Pressure Overload N Fukuma, I Russo, C Tzimas, W Dun, E Tsai Circulation 144 (Suppl_1), A14306-A14306, 2021 | | 2021 |
