WWM Pim Pijnappel
WWM Pim Pijnappel
Head of research group Molecular Stem Cell Biology, Erasmus MC Rotterdam
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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4
M Vermeulen, KW Mulder, S Denissov, WWMP Pijnappel, ...
Cell 131 (1), 58-69, 2007
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4
A Roguev, D Schaft, A Shevchenko, WWMP Pijnappel, M Wilm, ...
The EMBO journal 20 (24), 7137-7148, 2001
The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program
WWMP Pijnappel, D Schaft, A Roguev, A Shevchenko, H Tekotte, M Wilm, ...
Genes & development 15 (22), 2991-3004, 2001
The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification
WWM Pijnappel, HFJ Hendriks, GE Folkers, CE Van den Brink, EJ Dekker, ...
Nature 366 (6453), 340-344, 1993
ATAC-king the complexity of SAGA during evolution
G Spedale, HTM Timmers, WWMP Pijnappel
Genes & development 26 (6), 527-541, 2012
Human Ccr4–Not complexes contain variable deadenylase subunits
NC Lau, A Kolkman, FMA van Schaik, KW Mulder, WWMP Pijnappel, ...
Biochemical Journal 422 (3), 443-453, 2009
Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles
G Testa, Y Zhang, K Vintersten, V Benes, WWMP Pijnappel, I Chambers, ...
Nature biotechnology 21 (4), 443-447, 2003
European consensus for starting and stopping enzyme replacement therapy in adult patients with Pompe disease: a 10‐year experience
AT van der Ploeg, ME Kruijshaar, A Toscano, P LaforÍt, C Angelini, ...
European journal of neurology 24 (6), 768-e31, 2017
Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry: analytical perspective
A Shevchenko, D Schaft, A Roguev, WWMP Pijnappel, AF Stewart, ...
Molecular & Cellular Proteomics 1 (3), 204-212, 2002
Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels
AO Helbig, S Rosati, PWWM Pijnappel, B van Breukelen, MHTH Timmers, ...
BMC genomics 11 (1), 685, 2010
Noradrenaline release from streptolysin-O-permeated rat cortical synaptosomes: effects of calcium, phorbol esters, protein kinase inhibitors, and antibodies to the neuron†…
LV Dekker, PNE De Graan, P Pijnappel, AB Oestreicher, WH Gispen
Journal of Neurochemistry 56, 1146-1153, 1991
Opportunities and challenges for antisense oligonucleotide therapies
EC Kuijper, AJ Bergsma, WWMP Pijnappel, A Aartsma‐Rus
Journal of inherited metabolic disease 44 (1), 72-87, 2021
A central role for TFIID in the pluripotent transcription circuitry
WWMP Pijnappel, D Esch, MPA Baltissen, G Wu, N Mischerikow, ...
Nature 495 (7442), 516-519, 2013
Elevated plasma cardiac troponin T levels caused by skeletal muscle damage in Pompe disease
SCA Wens, GJ Schaaf, M Michels, ME Kruijshaar, TJM Van Gestel, ...
Circulation: cardiovascular genetics 9 (1), 6-13, 2016
Quantitative proteomics reveals regulation of dynamic components within TATA-binding protein (TBP) transcription complexes
F Mousson, A Kolkman, WWMP Pijnappel, HTM Timmers, AJR Heck
Molecular & Cellular Proteomics 7 (5), 845-852, 2008
Ready for repair? Gene editing enters the clinic for the treatment of human disease
MPT Ernst, M Broeders, P Herrero-Hernandez, E Oussoren, ...
Molecular Therapy-Methods & Clinical Development 18, 532-557, 2020
Sharpening the molecular scissors: advances in gene-editing technology
M Broeders, P Herrero-Hernandez, MPT Ernst, AT van der Ploeg, ...
Iscience 23 (1), 2020
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies
E van der Wal, P Herrero-Hernandez, R Wan, M Broeders, ...
Stem Cell Reports 10 (6), 1975-1990, 2018
Probing Genuine Strong Interactions and Post-translational Modifications in the Heterogeneous Yeast Exosome Protein Complex* S
SA Synowsky, RHH van den Heuvel, S Mohammed, WWMP Pijnappel, ...
Molecular & Cellular Proteomics 5 (9), 1581-1592, 2006
Autoinduction of retinoic acid metabolism to polar derivatives with decreased biological activity in retinoic acid-sensitive, but not in retinoic acid-resistant human breast†…
M Bas-jan, CE van den Brink, WWM Pijnappel, E Sonneveld, ...
Journal of Biological Chemistry 272 (29), 17921-17928, 1997
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