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Scott Oakes
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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis
L Scorrano, SA Oakes, JT Opferman, EH Cheng, MD Sorcinelli, T Pozzan, ...
Science 300 (5616), 135-139, 2003
17822003
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis
L Scorrano, M Ashiya, K Buttle, S Weiler, SA Oakes, CA Mannella, ...
Developmental cell 2 (1), 55-67, 2002
12732002
The role of endoplasmic reticulum stress in human pathology
SA Oakes, FR Papa
Annual Review of Pathology: Mechanisms of Disease 10, 173-194, 2015
12252015
IRE1α kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
D Han, AG Lerner, LV Walle, JP Upton, W Xu, A Hagen, BJ Backes, ...
Cell 138 (3), 562-575, 2009
9552009
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress
AG Lerner, JP Upton, PVK Praveen, R Ghosh, Y Nakagawa, A Igbaria, ...
Cell metabolism 16 (2), 250-264, 2012
8612012
Proteostasis control by the unfolded protein response
C Hetz, E Chevet, SA Oakes
Nature cell biology 17 (7), 829-838, 2015
7762015
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2
JP Upton, L Wang, D Han, ES Wang, NE Huskey, L Lim, M Truitt, ...
Science 338 (6108), 818-822, 2012
7162012
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
SA Oakes, L Scorrano, JT Opferman, MC Bassik, M Nishino, T Pozzan, ...
Proceedings of the National Academy of Sciences 102 (1), 105-110, 2005
5362005
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress
R Ghosh, L Wang, ES Wang, BGK Perera, A Igbaria, S Morita, K Prado, ...
Cell 158 (3), 534-548, 2014
4802014
Signaling cell death from the endoplasmic reticulum stress response
GC Shore, FR Papa, SA Oakes
Current opinion in cell biology 23 (2), 143-149, 2011
4732011
Phosphorylation of BCL‐2 regulates ER Ca2+ homeostasis and apoptosis
MC Bassik, L Scorrano, SA Oakes, T Pozzan, SJ Korsmeyer
The EMBO journal 23 (5), 1207-1216, 2004
3622004
Akt and autophagy cooperate to promote survival of drug-resistant glioma
QW Fan, C Cheng, C Hackett, M Feldman, BT Houseman, T Nicolaides, ...
Science signaling 3 (147), ra81-ra81, 2010
3432010
Endoplasmic reticulum stress signaling in cancer cells
SA Oakes
The American journal of pathology 190 (5), 934-946, 2020
2492020
Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors
L Wang, BGK Perera, SB Hari, B Bhhatarai, BJ Backes, MA Seeliger, ...
Nature chemical biology 8 (12), 982-989, 2012
2312012
Structural and functional basis for JAK3-deficient severe combined immunodeficiency
F Candotti, SA Oakes, JA Johnston, S Giliani, RF Schumacher, P Mella, ...
Blood, The Journal of the American Society of Hematology 90 (10), 3996-4003, 1997
2241997
Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress
JP Upton, K Austgen, M Nishino, KM Coakley, A Hagen, D Han, FR Papa, ...
Molecular and cellular biology 28 (12), 3943-3951, 2008
2172008
Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T Cells potential role of jak kinases
JA Johnston, LM Wang, EP Hanson, XJ Sun, MF White, SA Oakes, ...
Journal of Biological Chemistry 270 (48), 28527-28530, 1995
1901995
Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients
CA Crane, K Austgen, K Haberthur, C Hofmann, KW Moyes, L Avanesyan, ...
Proceedings of the National Academy of Sciences 111 (35), 12823-12828, 2014
1802014
Regulation of endoplasmic reticulum Ca2+ dynamics by proapoptotic BCL-2 family members
SA Oakes, JT Opferman, T Pozzan, SJ Korsmeyer, L Scorrano
Biochemical pharmacology 66 (8), 1335-1340, 2003
1752003
Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways
SA Oakes, F Candotti, JA Johnston, YQ Chen, JJ Ryan, N Taylor, X Liu, ...
Immunity 5 (6), 605-615, 1996
1571996
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