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Tom Houben
Tom Houben
Assistant Professor, Maastricht University
Geverifieerd e-mailadres voor maastrichtuniversity.nl
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The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management
T Yadati, T Houben, A Bitorina, R Shiri-Sverdlov
Cells 9 (7), 1679, 2020
2532020
Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids
AWF Janssen, T Houben, S Katiraei, W Dijk, L Boutens, N Van Der Bolt, ...
Journal of lipid research 58 (7), 1399-1416, 2017
1192017
Inflammatory Bowel Disease: A Stressed “Gut/Feeling”
Y Oligschlaeger, T Yadati, T Houben, CM Condello Oliván, ...
Cells 8 (7), 659, 2019
912019
Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice
T Hendrikx, MLJ Jeurissen, PJ van Gorp, MJ Gijbels, SMA Walenbergh, ...
The FEBS journal 282 (12), 2327-2338, 2015
722015
The immunity–diet–microbiota axis in the development of metabolic syndrome
E Brandsma, T Houben, J Fu, R Shiri-Sverdlov, MH Hofker
Current opinion in lipidology 26 (2), 73-81, 2015
582015
Cathepsin D regulates lipid metabolism in murine steatohepatitis
T Houben, Y Oligschlaeger, T Hendrikx, AV Bitorina, SMA Walenbergh, ...
Scientific reports 7 (1), 3494, 2017
532017
Plasma cathepsin D levels: a novel tool to predict pediatric hepatic inflammation
SMA Walenbergh, T Houben, T Hendrikx, MLJ Jeurissen, PJ Van Gorp, ...
Official journal of the American College of Gastroenterology| ACG 110 (3 …, 2015
492015
Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention
SMA Walenbergh, T Houben, SS Rensen, V Bieghs, T Hendrikx, ...
Scientific reports 6 (1), 38278, 2016
422016
Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr−/− mice
T Hendrikx, MLJ Jeurissen, V Bieghs, SMA Walenbergh, PJ van Gorp, ...
Journal of hepatology 62 (2), 430-436, 2015
282015
Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation
T Houben, Y Oligschlaeger, AV Bitorina, T Hendrikx, SMA Walenbergh, ...
Scientific reports 7 (1), 12550, 2017
252017
Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis
T Houben, E Brandsma, SMA Walenbergh, MH Hofker, R Shiri-Sverdlov
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017
252017
Weekly treatment of 2-hydroxypropyl-β-cyclodextrin improves intracellular cholesterol levels in LDL receptor knockout mice
SMA Walenbergh, T Houben, T Hendrikx, MLJ Jeurissen, PJ Van Gorp, ...
International journal of molecular sciences 16 (9), 21056-21069, 2015
242015
Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague–Dawley Rats
P Khurana, T Yadati, S Goyal, A Dolas, T Houben, Y Oligschlaeger, ...
Biomolecules 9 (5), 171, 2019
222019
MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis
D Chanda, J Li, Y Oligschlaeger, MLJ Jeurissen, T Houben, ...
Experimental & molecular medicine 48 (9), e258-e258, 2016
222016
Plasma cathepsin D activity rather than levels correlates with metabolic parameters of type 2 diabetes in male individuals
L Ding, T Houben, BJ Verwer, R Shiri-Sverdlov
Frontiers in Endocrinology 11, 575070, 2020
212020
Nonalcoholic fatty liver disease
L Ding, Y Oligschlaeger, R Shiri-Sverdlov, T Houben
Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art …, 2020
212020
Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr−/− mice
MLJ Jeurissen, SMA Walenbergh, T Houben, MJJ Gijbels, J Li, T Hendrikx, ...
Atherosclerosis 255, 59-65, 2016
202016
Macrophage stimulating protein enhances hepatic inflammation in a NASH model
J Li, D Chanda, PJ van Gorp, MLJ Jeurissen, T Houben, ...
PLoS One 11 (9), e0163843, 2016
182016
Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans
L Ding, GH Goossens, Y Oligschlaeger, T Houben, EE Blaak, ...
Diabetologia 63, 374-384, 2020
172020
Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low‐Density Lipoprotein Receptor …
F Ahmad, RD Mitchell, T Houben, A Palo, T Yadati, AJ Parnell, K Patel, ...
Journal of the American Heart Association 10 (18), e017524, 2021
162021
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Artikelen 1–20