Mass-spectrometry-based draft of the human proteome M Wilhelm, J Schlegl, H Hahne, AM Gholami, M Lieberenz, MM Savitski, ... Nature 509 (7502), 582-587, 2014 | 2063 | 2014 |
Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics PJ Boersema, R Raijmakers, S Lemeer, S Mohammed, AJR Heck Nature protocols 4 (4), 484-494, 2009 | 1583 | 2009 |
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present M Bantscheff, S Lemeer, MM Savitski, B Kuster Analytical and bioanalytical chemistry 404, 939-965, 2012 | 1002 | 2012 |
Confident phosphorylation site localization using the Mascot Delta Score MM Savitski, S Lemeer, M Boesche, M Lang, T Mathieson, M Bantscheff, ... Molecular & cellular proteomics 10 (2), S1-S12, 2011 | 311 | 2011 |
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments H Hahne, F Pachl, B Ruprecht, SK Maier, S Klaeger, D Helm, G Médard, ... Nature methods 10 (10), 989-991, 2013 | 248 | 2013 |
The phosphoproteomics data explosion S Lemeer, AJR Heck Current opinion in chemical biology 13 (4), 414-420, 2009 | 208 | 2009 |
In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling PJ Boersema, LY Foong, VMY Ding, S Lemeer, B van Breukelen, R Philp, ... Molecular & Cellular Proteomics 9 (1), 84-99, 2010 | 198 | 2010 |
Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death K Neumann, M Castineiras-Vilarino, U Höckendorf, N Hannesschläger, ... Immunity 40 (3), 389-399, 2014 | 193 | 2014 |
A large synthetic peptide and phosphopeptide reference library for mass spectrometry–based proteomics H Marx, S Lemeer, JE Schliep, L Matheron, S Mohammed, J Cox, M Mann, ... Nature biotechnology 31 (6), 557-564, 2013 | 191 | 2013 |
Immunomodulatory drugs disrupt the cereblon–CD147–MCT1 axis to exert antitumor activity and teratogenicity R Eichner, M Heider, V Fernández-Sáiz, F van Bebber, AK Garz, ... Nature medicine 22 (7), 735-743, 2016 | 178 | 2016 |
Meltome atlas—thermal proteome stability across the tree of life A Jarzab, N Kurzawa, T Hopf, M Moerch, J Zecha, N Leijten, Y Bian, ... Nature methods 17 (5), 495-503, 2020 | 175 | 2020 |
Differential oxidation of protein-tyrosine phosphatases A Groen, S Lemeer, T van der Wijk, J Overvoorde, AJR Heck, A Ostman, ... Journal of Biological Chemistry 280 (11), 10298-10304, 2005 | 170 | 2005 |
EGFR dynamics change during activation in native membranes as revealed by NMR M Kaplan, S Narasimhan, C De Heus, D Mance, S Van Doorn, K Houben, ... Cell 167 (5), 1241-1251. e11, 2016 | 169 | 2016 |
Widespread bacterial protein histidine phosphorylation revealed by mass spectrometry-based proteomics CM Potel, MH Lin, AJR Heck, S Lemeer Nature methods 15 (3), 187-190, 2018 | 157 | 2018 |
A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination E Klapisz, I Sorokina, S Lemeer, M Pijnenburg, AJ Verkleij, ... Journal of Biological Chemistry 277 (34), 30746-30753, 2002 | 135 | 2002 |
Comprehensive and reproducible phosphopeptide enrichment using iron immobilized metal ion affinity chromatography (Fe-IMAC) columns B Ruprecht, H Koch, G Medard, M Mundt, B Kuster, S Lemeer Molecular & Cellular Proteomics 14 (1), 205-215, 2015 | 132 | 2015 |
Reversible oxidation of the membrane distal domain of receptor PTPα is mediated by a cyclic sulfenamide J Yang, A Groen, S Lemeer, A Jans, M Slijper, SM Roe, J den Hertog, ... Biochemistry 46 (3), 709-719, 2007 | 123 | 2007 |
Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics D Helm, JPC Vissers, CJ Hughes, H Hahne, B Ruprecht, F Pachl, A Grzyb, ... Molecular & Cellular Proteomics 13 (12), 3709-3715, 2014 | 121 | 2014 |
Phosphopeptide fragmentation and site localization by mass spectrometry: an update CM Potel, S Lemeer, AJR Heck Analytical chemistry 91 (1), 126-141, 2018 | 108 | 2018 |
SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma V Fernández-Sáiz, BS Targosz, S Lemeer, R Eichner, C Langer, ... Nature cell biology 15 (1), 72-81, 2013 | 106 | 2013 |