Johan W. Jonker
Johan W. Jonker
Professor, University Medical Center Groningen
Verified email at - Homepage
Cited by
Cited by
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
AH Schinkel, JW Jonker
Advanced drug delivery reviews 64, 138-153, 2012
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
JW Jonker, M Buitelaar, E Wagenaar, MA Van Der Valk, GL Scheffer, ...
Proceedings of the National Academy of Sciences 99 (24), 15649-15654, 2002
Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
JW Jonker, JW Smit, RF Brinkhuis, M Maliepaard, JH Beijnen, ...
Journal of the National Cancer Institute 92 (20), 1651-1656, 2000
Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin
DS Wang, JW Jonker, Y Kato, H Kusuhara, AH Schinkel, Y Sugiyama
Journal of Pharmacology and Experimental Therapeutics 302 (2), 510-515, 2002
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
JW Jonker, G Merino, S Musters, AE van Herwaarden, E Bolscher, ...
Nature medicine 11 (2), 127-129, 2005
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
KA Lamia, SJ Papp, TY Ruth, GD Barish, NH Uhlenhaut, JW Jonker, ...
Nature 480 (7378), 552-556, 2011
Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3)
JW Jonker, AH Schinkel
Journal of Pharmacology and Experimental Therapeutics 308 (1), 2-9, 2004
Short-chain fatty acids protect against high-fat diet–induced obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation
G den Besten, A Bleeker, A Gerding, K van Eunen, R Havinga, ...
Diabetes 64 (7), 2398-2408, 2015
Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo (4, 5-b) pyridine, and transport of …
P Pavek, G Merino, E Wagenaar, E Bolscher, M Novotna, JW Jonker, ...
Journal of Pharmacology and Experimental Therapeutics 312 (1), 144-152, 2005
The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine
AE van Herwaarden, JW Jonker, E Wagenaar, RF Brinkhuis, ...
Cancer research 63 (19), 6447-6452, 2003
ERRγ directs and maintains the transition to oxidative metabolism in the postnatal heart
WA Alaynick, RP Kondo, W Xie, W He, CR Dufour, M Downes, JW Jonker, ...
Cell metabolism 6 (1), 13-24, 2007
Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene
JW Jonker, E Wagenaar, CAAM Mol, M Buitelaar, H Koepsell, JW Smit, ...
Molecular and Cellular Biology 21 (16), 5471-5477, 2001
Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk
AE van Herwaarden, E Wagenaar, G Merino, JW Jonker, H Rosing, ...
Molecular and cellular biology 27 (4), 1247-1253, 2007
Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations
JW Jonker, E Wagenaar, S van Eijl, AH Schinkel
Molecular and Cellular Biology 23 (21), 7902-7908, 2003
The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin
G Merino, JW Jonker, E Wagenaar, AE van Herwaarden, AH Schinkel
Molecular pharmacology 67 (5), 1758-1764, 2005
Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin
DS Wang, H Kusuhara, Y Kato, JW Jonker, AH Schinkel, Y Sugiyama
Molecular pharmacology 63 (4), 844-848, 2003
A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis
JW Jonker, JM Suh, AR Atkins, M Ahmadian, P Li, J Whyte, M He, ...
Nature 485 (7398), 391-394, 2012
Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice
JW Jonker, J Freeman, E Bolscher, S Musters, AJ Alvi, I Titley, ...
Stem cells 23 (8), 1059-1065, 2005
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells
K Thedieck, B Holzwarth, MT Prentzell, C Boehlke, K Kläsener, S Ruf, ...
Cell 154 (4), 859-874, 2013
Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk
AE Herwaarden, E Wagenaar, B Karnekamp, G Merino, JW Jonker, ...
Carcinogenesis 27 (1), 123-130, 2005
The system can't perform the operation now. Try again later.
Articles 1–20