| Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ... Nature protocols 2 (11), 2692, 2007 | 2025 | 2007 |
| Human metabolic phenotype diversity and its association with diet and blood pressure E Holmes, RL Loo, J Stamler, M Bictash, IKS Yap, Q Chan, T Ebbels, ... Nature 453 (7193), 396-400, 2008 | 1118 | 2008 |
| Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project JC Lindon, JK Nicholson, E Holmes, H Antti, ME Bollard, H Keun, ... Toxicology and applied pharmacology 187 (3), 137-146, 2003 | 505 | 2003 |
| Proposed minimum reporting standards for data analysis in metabolomics R Goodacre, D Broadhurst, AK Smilde, BS Kristal, JD Baker, R Beger, ... Metabolomics 3 (3), 231-241, 2007 | 459 | 2007 |
| High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues O Beckonert, M Coen, HC Keun, Y Wang, T Ebbels, E Holmes, JC Lindon, ... Nature protocols 5 (6), 1019-1032, 2010 | 381 | 2010 |
| Recursive Segment-Wise Peak Alignment of Biological 1H NMR Spectra for Improved Metabolic Biomarker Recovery KA Veselkov, JC Lindon, TMD Ebbels, D Crockford, VV Volynkin, ... Analytical chemistry 81 (1), 56-66, 2009 | 351 | 2009 |
| Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA A Kamburov, R Cavill, TMD Ebbels, R Herwig, HC Keun Bioinformatics 27 (20), 2917-2918, 2011 | 321 | 2011 |
| The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements JC Lindon, HC Keun, TMD Ebbels, JMT Pearce, E Holmes, JK Nicholson Future Medicine Ltd 6 (7), 691-699, 2005 | 315 | 2005 |
| Analytical reproducibility in 1H NMR-based metabonomic urinalysis HC Keun, TMD Ebbels, H Antti, ME Bollard, O Beckonert, G Schlotterbeck, ... Chemical research in toxicology 15 (11), 1380-1386, 2002 | 312 | 2002 |
| Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery KA Veselkov, LK Vingara, P Masson, SL Robinette, E Want, JV Li, ... Analytical chemistry 83 (15), 5864-5872, 2011 | 273 | 2011 |
| Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling HC Keun, TMD Ebbels, H Antti, ME Bollard, O Beckonert, E Holmes, ... Analytica chimica acta 490 (1-2), 265-276, 2003 | 218 | 2003 |
| Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues Y Wang, ME Bollard, H Keun, H Antti, O Beckonert, TM Ebbels, JC Lindon, ... Analytical biochemistry 323 (1), 26-32, 2003 | 206 | 2003 |
| Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach TMD Ebbels, HC Keun, OP Beckonert, ME Bollard, JC Lindon, E Holmes, ... Journal of proteome research 6 (11), 4407-4422, 2007 | 198 | 2007 |
| Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS P Masson, AC Alves, TMD Ebbels, JK Nicholson, EJ Want Analytical Chemistry 82 (18), 7779-7786, 2010 | 189 | 2010 |
| NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches O Beckonert, ME Bollard, TMD Ebbels, HC Keun, H Antti, E Holmes, ... Analytica Chimica Acta 490 (1-2), 3-15, 2003 | 172 | 2003 |
| Urinary metabolic signatures of human adiposity P Elliott, JM Posma, Q Chan, I Garcia-Perez, A Wijeyesekera, M Bictash, ... Science translational medicine 7 (285), 285ra62-285ra62, 2015 | 164 | 2015 |
| Design and analysis of metabolomics studies in epidemiologic research: a primer on-omic technologies I Tzoulaki, TMD Ebbels, A Valdes, P Elliott, JPA Ioannidis American journal of epidemiology 180 (2), 129-139, 2014 | 162 | 2014 |
| Opening up the" Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology M Bictash, TM Ebbels, Q Chan, RL Loo, IKS Yap, IJ Brown, M De Iorio, ... Journal of clinical epidemiology 63 (9), 970-979, 2010 | 162 | 2010 |
| Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles HC Keun, TMD Ebbels, ME Bollard, O Beckonert, H Antti, E Holmes, ... Chemical Research in Toxicology 17 (5), 579-587, 2004 | 160 | 2004 |
| Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN J Hao, M Liebeke, W Astle, M De Iorio, JG Bundy, TMD Ebbels Nature protocols 9 (6), 1416-1427, 2014 | 159 | 2014 |
Elaine HolmesMurdoch University & Imperial College LondonVerified email at imperial.ac.uk
