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Alex X. Li
Alex X. Li
Verified email at uwo.ca
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Year
Quantitative tissue pH measurement during cerebral ischemia using amine and amide concentration-independent detection (AACID) with MRI
N McVicar, AX Li, DF Goncalves, M Bellyou, SO Meakin, MAM Prado, ...
Journal of Cerebral Blood Flow & Metabolism 34 (4), 690-698, 2014
1932014
A sensitive PARACEST contrast agent for temperature MRI: Eu3+‐DOTAM‐glycine (Gly)‐phenylalanine (Phe)
AX Li, F Wojciechowski, M Suchy, CK Jones, RHE Hudson, RS Menon, ...
Magnetic Resonance in Medicine: An Official Journal of the International …, 2008
1282008
Four‐pool modeling of proton exchange processes in biological systems in the presence of MRI–paramagnetic chemical exchange saturation transfer (PARACEST) agents
AX Li, RHE Hudson, JW Barrett, CK Jones, SH Pasternak, R Bartha
Magnetic Resonance in Medicine: An Official Journal of the International …, 2008
1252008
Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission
MS Guzman, X De Jaeger, S Raulic, IA Souza, AX Li, S Schmid, ...
PLoS biology 9 (11), e1001194, 2011
1152011
Simultaneous in vivo pH and temperature mapping using a PARACEST‐MRI contrast agent
N McVicar, AX Li, M Suchý, RHE Hudson, RS Menon, R Bartha
Magnetic Resonance in Medicine 70 (4), 1016-1025, 2013
912013
A Robust and Convergent Synthesis of Dipeptide− DOTAM Conjugates as Chelators for Lanthanide Ions: New PARACEST MRI Agents
F Wojciechowski, M Suchy, AX Li, HA Azab, R Bartha, RHE Hudson
Bioconjugate chemistry 18 (5), 1625-1636, 2007
552007
Topiramate induces acute intracellular acidification in glioblastoma
K Marathe, N McVicar, A Li, M Bellyou, S Meakin, R Bartha
Journal of neuro-oncology 130, 465-472, 2016
452016
A paramagnetic chemical exchange-based MRI probe metabolized by cathepsin D: design, synthesis and cellular uptake studies
M Suchý, R Ta, AX Li, F Wojciechowski, SH Pasternak, R Bartha, ...
Organic & Biomolecular Chemistry 8 (11), 2560-2566, 2010
442010
Dichloroacetate induced intracellular acidification in glioblastoma: in vivo detection using AACID-CEST MRI at 9.4 Tesla
M Albatany, A Li, S Meakin, R Bartha
Journal of neuro-oncology 136 (2), 255-262, 2018
432018
Imaging chemical exchange saturation transfer (CEST) effects following tumor‐selective acidification using lonidamine
N McVicar, AX Li, SO Meakin, R Bartha
NMR in Biomedicine 28 (5), 566-575, 2015
432015
In vivo detection of MRI‐PARACEST agents in mouse brain tumors at 9.4 T
AX Li, M Suchy, C Li, JS Gati, S Meakin, RHE Hudson, RS Menon, ...
Magnetic Resonance in Medicine 66 (1), 67-72, 2011
372011
ParaCEST MRI contrast agents capable of derivatization via “click” chemistry
M Milne, K Chicas, A Li, R Bartha, RHE Hudson
Organic & Biomolecular Chemistry 10 (2), 287-292, 2012
332012
Analogs of Eu3+ DOTAM-Gly-Phe-OH and Tm3+ DOTAM-Gly-Lys-OH: Synthesis and magnetic properties of potential PARACEST MRI contrast agents
M Suchý, AX Li, R Bartha, RHE Hudson
Bioorganic & medicinal chemistry 16 (11), 6156-6166, 2008
262008
Reproducibility of neurite orientation dispersion and density imaging (NODDI) in rats at 9.4 Tesla
P McCunn, KM Gilbert, P Zeman, AX Li, MJ Strong, AR Khan, R Bartha
PLoS One 14 (4), e0215974, 2019
252019
In vivo detection of acute intracellular acidification in glioblastoma multiforme following a single dose of cariporide
M Albatany, A Li, S Meakin, R Bartha
International Journal of Clinical Oncology 23, 812-819, 2018
242018
Diffusion-weighted tractography in the common marmoset monkey at 9.4 T
DJ Schaeffer, R Adam, KM Gilbert, JS Gati, AX Li, RS Menon, S Everling
Journal of neurophysiology 118 (2), 1344-1354, 2017
232017
In vivo detection of PARACEST agents with relaxation correction
CK Jones, AX Li, M Suchý, RHE Hudson, RS Menon, R Bartha
Magnetic resonance in medicine 63 (5), 1184-1192, 2010
212010
A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin‐D detection
R Ta, M Suchy, JHK Tam, AX Li, FS Martinez‐Santiesteban, TJ Scholl, ...
Contrast media & molecular imaging 8 (2), 127-139, 2013
202013
A bifunctional chelator featuring the DOTAM-Gly-l-Phe-OH structural subunit: en route toward homo- and heterobimetallic lanthanide(III) complexes as PARACEST …
M Suchý, AX Li, R Bartha, RHE Hudson
Tetrahedron Letters 51 (7), 1087-1090, 2010
142010
A new synthesis of cystamine modified Eu 3+ DOTAM-Gly-Phe-OH: a conjugation ready temperature sensitive MRI contrast agent
M Suchý, AX Li, R Bartha, RHE Hudson
Organic & Biomolecular Chemistry 6 (19), 3588-3596, 2008
132008
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