| c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis Z Han, DL Boyle, L Chang, B Bennett, M Karin, L Yang, AM Manning, ... The Journal of clinical investigation 108 (1), 73-81, 2001 | 997 | 2001 |
| Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ... Nature immunology 20 (7), 928-942, 2019 | 858 | 2019 |
| Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist HM Hoffman, S Rosengren, DL Boyle, JY Cho, J Nayar, JL Mueller, ... The Lancet 364 (9447), 1779-1785, 2004 | 659 | 2004 |
| AP-1 and NF-kB regulation in rheumatoid arthritis and murine collagen-induced arthritis Z Han, DL Boyle, AM Manning, GS Firestein Autoimmunity 28 (4), 197-208, 1998 | 503 | 1998 |
| DNA methylome signature in rheumatoid arthritis K Nakano, JW Whitaker, DL Boyle, W Wang, GS Firestein Annals of the rheumatic diseases 72 (1), 110-117, 2013 | 376 | 2013 |
| Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity SD Brydges, JL Mueller, MD McGeough, CA Pena, A Misaghi, C Gandhi, ... Immunity 30 (6), 875-887, 2009 | 345 | 2009 |
| Synergistic benefit in inflammatory arthritis by targeting IκB kinase ϵ and interferon β M Corr, DL Boyle, L Ronacher, N Flores, GS Firestein Annals of the rheumatic diseases 68 (2), 257-263, 2009 | 340* | 2009 |
| Inhibitor of nuclear factor κB kinase β is a key regulator of synovial inflammation PP Tak, DM Gerlag, KR Aupperle, DA Van De Geest, M Overbeek, ... Arthritis & Rheumatism 44 (8), 1897-1907, 2001 | 309 | 2001 |
| The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis DL Boyle, K Soma, J Hodge, A Kavanaugh, D Mandel, P Mease, ... Annals of the rheumatic diseases 74 (6), 1311-1316, 2015 | 299 | 2015 |
| Regional analysis of p53 mutations in rheumatoid arthritis synovium Y Yamanishi, DL Boyle, S Rosengren, DR Green, NJ Zvaifler, ... Proceedings of the National Academy of Sciences 99 (15), 10025-10030, 2002 | 284 | 2002 |
| Synovial interleukin‐1 receptor antagonist and interleukin‐1 balance in rheumatoid arthritis GS Firestein, DL Boyle, C Yu, MM Paine, TD Whisenand, NJ Zvaifler, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1994 | 275 | 1994 |
| Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines J Ohata, NJ Zvaifler, M Nishio, DL Boyle, SL Kalled, DA Carson, TJ Kipps The Journal of Immunology 174 (2), 864-870, 2005 | 274 | 2005 |
| Synovial tissue research: a state-of-the-art review C Orr, E Vieira-Sousa, DL Boyle, MH Buch, CD Buckley, JD Cañete, ... Nature Reviews Rheumatology 13 (8), 463-475, 2017 | 248 | 2017 |
| Expression and regulation of aggrecanase in arthritis: the role of TGF-β Y Yamanishi, DL Boyle, M Clark, RA Maki, MD Tortorella, EC Arner, ... The Journal of Immunology 168 (3), 1405-1412, 2002 | 245 | 2002 |
| Apoptosis in rheumatoid arthritis: p53 overexpression in rheumatoid arthritis synovium. GS Firestein, K Nguyen, KR Aupperle, M Yeo, DL Boyle, NJ Zvaifler The American journal of pathology 149 (6), 2143, 1996 | 228 | 1996 |
| Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors. MG Bouma, TM Jeunhomme, DL Boyle, MA Dentener, NN Voitenok, ... Journal of immunology (Baltimore, Md.: 1950) 158 (11), 5400-5408, 1997 | 216 | 1997 |
| Assessment of rituximab’s immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results A Kavanaugh, S Rosengren, SJ Lee, D Hammaker, GS Firestein, ... Annals of the rheumatic diseases 67 (3), 402-408, 2008 | 207 | 2008 |
| Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor gene. KR Aupperle, DL Boyle, M Hendrix, EA Seftor, NJ Zvaifler, M Barbosa, ... The American journal of pathology 152 (4), 1091, 1998 | 198 | 1998 |
| Jun N-terminal kinase in rheumatoid arthritis Z Han, DL Boyle, KR Aupperle, B Bennett, AM Manning, GS Firestein Journal of Pharmacology and Experimental Therapeutics 291 (1), 124-130, 1999 | 189 | 1999 |
| Prostaglandins increase proMMP-1 and proMMP-3 secretion by human ciliary smooth muscle cells JD Lindsey, K Kashiwagi, D Boyle, F Kashiwagi, GS Firestein, ... Current eye research 15 (8), 869-875, 1996 | 189 | 1996 |
