Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail J Hansen, A Baum, KE Pascal, V Russo, S Giordano, E Wloga, BO Fulton, ... Science 369 (6506), 1010-1014, 2020 | 975 | 2020 |
Quantitation of DNA double-strand break resection intermediates in human cells Y Zhou, P Caron, G Legube, TT Paull Nucleic acids research 42 (3), e19, 2014 | 249 | 2014 |
Identification of niclosamide as a new small-molecule inhibitor of the STAT3 signaling pathway X Ren, L Duan, Q He, Z Zhang, Y Zhou, D Wu, J Pan, D Pei, K Ding ACS medicinal chemistry letters 1 (9), 454-459, 2010 | 245 | 2010 |
Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection N Makharashvili, AT Tubbs, SH Yang, H Wang, O Barton, Y Zhou, ... Molecular cell 54 (6), 1022-1033, 2014 | 211 | 2014 |
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies R Copin, A Baum, E Wloga, KE Pascal, S Giordano, BO Fulton, A Zhou, ... Cell 184 (15), 3949-3961. e11, 2021 | 188 | 2021 |
Human Mre11/human Rad50/Nbs1 and DNA ligase IIIα/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway J Della-Maria, Y Zhou, MS Tsai, J Kuhnlein, JP Carney, TT Paull, ... Journal of Biological Chemistry 286 (39), 33845-33853, 2011 | 168 | 2011 |
Regulation of the DNA damage response by DNA-PKcs inhibitory phosphorylation of ATM Y Zhou, JH Lee, W Jiang, JL Crowe, S Zha, TT Paull Molecular cell 65 (1), 91-104, 2017 | 138 | 2017 |
Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins LR Myler, IF Gallardo, Y Zhou, F Gong, SH Yang, MS Wold, KM Miller, ... Proceedings of the National Academy of Sciences 113 (9), E1170-E1179, 2016 | 110 | 2016 |
Cas4-dependent prespacer processing ensures high-fidelity programming of CRISPR arrays H Lee, Y Zhou, DW Taylor, DG Sashital Molecular cell 70 (1), 48-59. e5, 2018 | 106 | 2018 |
ATM directs DNA damage responses and proteostasis via genetically separable pathways JH Lee, MR Mand, CH Kao, Y Zhou, SW Ryu, AL Richards, JJ Coon, ... Science signaling 11 (512), eaan5598, 2018 | 103 | 2018 |
Supercharging enables organized assembly of synthetic biomolecules AJ Simon, Y Zhou, V Ramasubramani, J Glaser, A Pothukuchy, J Gollihar, ... Nature chemistry 11 (3), 204-212, 2019 | 79 | 2019 |
DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM) Y Zhou, TT Paull Journal of Biological Chemistry 288 (52), 37112-37125, 2013 | 74 | 2013 |
Effects of an AMP-activated protein kinase inhibitor, compound C, on adipogenic differentiation of 3T3-L1 cells Y Gao, Y Zhou, A Xu, D Wu Biological and Pharmaceutical Bulletin 31 (9), 1716-1722, 2008 | 72 | 2008 |
Inhibitory effects of A-769662, a novel activator of AMP-activated protein kinase, on 3T3-L1 adipogenesis Y Zhou, D Wang, Q Zhu, X Gao, S Yang, A Xu, D Wu Biological and Pharmaceutical Bulletin 32 (6), 993-998, 2009 | 65 | 2009 |
Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome Y Zhou, S Musalgaonkar, AW Johnson, DW Taylor Nature communications 10 (1), 958, 2019 | 56 | 2019 |
Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21) X Huang, M Beullens, J Zhang, Y Zhou, E Nicolaescu, B Lesage, Q Hu, ... Journal of biological chemistry 284 (37), 25375-25387, 2009 | 54 | 2009 |
Structure of a type IV CRISPR-Cas ribonucleoprotein complex Y Zhou, JPK Bravo, HN Taylor, JA Steens, RN Jackson, RHJ Staals, ... Iscience 24 (3), 2021 | 23 | 2021 |
Separating distinct structures of multiple macromolecular assemblies from cryo-EM projections EJ Verbeke, Y Zhou, AP Horton, AL Mallam, DW Taylor, EM Marcotte Journal of structural biology 209 (1), 107416, 2020 | 22 | 2020 |
Direct measurement of single-stranded DNA intermediates in mammalian cells by quantitative polymerase chain reaction Y Zhou, TT Paull Analytical biochemistry 479, 48-50, 2015 | 21 | 2015 |
Structural insights into the assembly of gp130 family cytokine signaling complexes Y Zhou, PE Stevis, J Cao, K Saotome, J Wu, A Glatman Zaretsky, ... Science Advances 9 (11), eade4395, 2023 | 17 | 2023 |