Jeroen den Dunnen
Jeroen den Dunnen
Associate Professor, AMC Amsterdam
Geverifieerd e-mailadres voor amsterdamumc.nl
Geciteerd door
Geciteerd door
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-κB
SI Gringhuis, J den Dunnen, M Litjens, B van Het Hof, Y van Kooyk, ...
Immunity 26 (5), 605-616, 2007
Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk
SI Gringhuis, J Den Dunnen, M Litjens, M Van Der Vlist, B Wevers, ...
Nature immunology 10 (2), 203-213, 2009
Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori
SI Gringhuis, J Den Dunnen, M Litjens, M Van Der Vlist, TBH Geijtenbeek
Nature immunology 10 (10), 1081-1088, 2009
HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells
SI Gringhuis, M Van Der Vlist, LM Van Den Berg, J Den Dunnen, M Litjens, ...
Nature immunology 11 (5), 419-426, 2010
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ...
Science 371 (6532), eabc8378, 2021
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages
W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ...
Science translational medicine 13 (596), eabf8654, 2021
Innate signaling and regulation of dendritic cell immunity
SJ Van Vliet, J den Dunnen, SI Gringhuis, TBH Geijtenbeek, Y van Kooyk
Current opinion in immunology 19 (4), 435-440, 2007
Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization
JWR Hovius, MAWP de Jong, J den Dunnen, M Litjens, E Fikrig, ...
PLoS pathogens 4 (2), e31, 2008
Innate signaling by the C-type lectin DC-SIGN dictates immune responses
J Den Dunnen, SI Gringhuis, TBH Geijtenbeek
Cancer Immunology, Immunotherapy 58, 1149-1157, 2009
Control of cytokine production by human fc gamma receptors: implications for pathogen defense and autoimmunity
LTC Vogelpoel, DLP Baeten, EC de Jong, J Den Dunnen
Frontiers in immunology 6, 79, 2015
Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages
LTC Vogelpoel, IS Hansen, T Rispens, FJM Muller, TMM Van Capel, ...
Nature communications 5 (1), 5444, 2014
The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium–host interaction
BJ Appelmelk, J Den Dunnen, NN Driessen, R Ummels, M Pak, J Nigou, ...
Cellular microbiology 10 (4), 930-944, 2008
The inflammatory function of human IgA
IS Hansen, DLP Baeten, J den Dunnen
Cellular and molecular life sciences 76 (6), 1041-1055, 2019
Pathogen recognition by DC-SIGN shapes adaptive immunity
TBH Geijtenbeek, J Den Dunnen, SI Gringhuis
Future microbiology 4 (7), 879-890, 2009
IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells
J Den Dunnen, LTC Vogelpoel, T Wypych, FJM Muller, L de Boer, ...
Blood, The Journal of the American Society of Hematology 120 (1), 112-121, 2012
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets
AP Bye, W Hoepel, JL Mitchell, S Jégouic, S Loureiro, T Sage, ...
Blood, The Journal of the American Society of Hematology 138 (16), 1481-1489, 2021
Serum IgA immune complexes promote proinflammatory cytokine production by human macrophages, monocytes, and Kupffer cells through FcαRI–TLR cross-talk
IS Hansen, W Hoepel, SAJ Zaat, DLP Baeten, J den Dunnen
The Journal of Immunology 199 (12), 4124-4131, 2017
FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells
LTC Vogelpoel, IS Hansen, MW Visser, SQ Nagelkerke, TW Kuijpers, ...
Immunobiology 220 (2), 193-199, 2015
Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis
CW Wieland, EA Koppel, J den Dunnen, S Florquin, ANJ McKenzie, ...
Microbes and infection 9 (2), 134-141, 2007
FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming
IS Hansen, L Krabbendam, JH Bernink, F Loayza-Puch, W Hoepel, ...
Nature communications 9 (1), 863, 2018
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