Mechanisms of action of CD20 antibodies P Boross, JHW Leusen American journal of cancer research 2 (6), 676, 2012 | 273 | 2012 |
Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab J Golay, F Da Roit, L Bologna, C Ferrara, JH Leusen, A Rambaldi, C Klein, ... Blood, The Journal of the American Society of Hematology 122 (20), 3482-3491, 2013 | 246 | 2013 |
Mac-1 (CD11b/CD18) is essential for Fc receptor–mediated neutrophil cytotoxicity and immunologic synapse formation AB van Spriel, JHW Leusen, M van Egmond, HBPM Dijkman, ... Blood, The Journal of the American Society of Hematology 97 (8), 2478-2486, 2001 | 231 | 2001 |
The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcγ receptor–mediated cross-linking MB Overdijk, JHM Jansen, M Nederend, JJL van Bueren, RWJ Groen, ... The Journal of Immunology 197 (3), 807-813, 2016 | 217 | 2016 |
Crosstalk between human IgG isotypes and murine effector cells MB Overdijk, S Verploegen, AO Buijsse, T Vink, JHW Leusen, WK Bleeker, ... The Journal of Immunology 189 (7), 3430-3438, 2012 | 200 | 2012 |
Functional characteristics of the high affinity IgG receptor, FcγRI CE van der Poel, RM Spaapen, JGJ van de Winkel, JHW Leusen The Journal of Immunology 186 (5), 2699-2704, 2011 | 172 | 2011 |
Neutrophils kill antibody-opsonized cancer cells by trogoptosis HL Matlung, L Babes, XW Zhao, M van Houdt, LW Treffers, DJ van Rees, ... Cell Reports 23 (13), 3946-3959. e6, 2018 | 169 | 2018 |
Interactions between the components of the human NADPH oxidase: intrigues in the phox family JHW Leusen, AJ Verhoeven, D Roos Journal of Laboratory and Clinical Medicine 128 (5), 461-476, 1996 | 152 | 1996 |
In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling S de Haij, JHM Jansen, P Boross, FJ Beurskens, JE Bakema, DL Bos, ... Cancer research 70 (8), 3209-3217, 2010 | 137 | 2010 |
156Pro--> Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and … JH Leusen, BG Bolscher, PM Hilarius, RS Weening, W Kaulfersch, ... The Journal of experimental medicine 180 (6), 2329-2334, 1994 | 136 | 1994 |
The high-affinity IgG receptor, FcγRI, plays a central role in antibody therapy of experimental melanoma L Bevaart, MJH Jansen, MJ van Vugt, JS Verbeek, JGJ van de Winkel, ... Cancer research 66 (3), 1261-1264, 2006 | 134 | 2006 |
Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden A Åhlin, M De Boer, D Roos, J Leusen, CIE Smith, U Sundin, H Rabbani, ... Acta paediatrica 84 (12), 1386-1394, 1995 | 118 | 1995 |
A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox. JH Leusen, M De Boer, BG Bolscher, PM Hilarius, RS Weening, HD Ochs, ... The Journal of clinical investigation 93 (5), 2120-2126, 1994 | 118 | 1994 |
The importance of human FcγRI in mediating protection to malaria RS McIntosh, J Shi, RM Jennings, JC Chappel, TF de Koning-Ward, ... PLoS pathogens 3 (5), e72, 2007 | 112 | 2007 |
Effects of bovine immunoglobulins on immune function, allergy, and infection LH Ulfman, JHW Leusen, HFJ Savelkoul, JO Warner, RJJ Van Neerven Frontiers in nutrition 5, 52, 2018 | 103 | 2018 |
IgA EGFR antibodies mediate tumour killing in vivo P Boross, S Lohse, M Nederend, JHM Jansen, G van Tetering, M Dechant, ... EMBO molecular medicine 5 (8), 1213-1226, 2013 | 103 | 2013 |
Plant-derived anti-Lewis Y mAb exhibits biological activities for efficient immunotherapy against human cancer cells R Brodzik, M Glogowska, K Bandurska, M Okulicz, D Deka, K Ko, ... Proceedings of the National Academy of Sciences 103 (23), 8804-8809, 2006 | 97 | 2006 |
Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease. JH Leusen, A de Klein, PM Hilarius, A Ahlin, J Palmblad, CI Smith, ... The Journal of experimental medicine 184 (4), 1243-1249, 1996 | 96 | 1996 |
Cytolytic mechanisms and expression of activation-regulating receptors on effector-type CD8+ CD45RA+ CD27− human T cells PA Baars, LMR do Couto, JHW Leusen, B Hooibrink, TW Kuijpers, ... The Journal of Immunology 165 (4), 1910-1917, 2000 | 94 | 2000 |
Interactions between the components of the human NADPH oxidase: a review about the intrigues in the phox family JHW Leusen, AJ Verhoeven, D Roos Frontiers in Bioscience-Landmark 1 (4), 72-90, 1996 | 94 | 1996 |