Jeanette Leusen
Jeanette Leusen
associate prof Immunotherapie, UMC Utrecht
Geverifieerd e-mailadres voor umcutrecht.nl - Homepage
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Mechanisms of action of CD20 antibodies
P Boross, JHW Leusen
American journal of cancer research 2 (6), 676, 2012
2372012
Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab
J Golay, F Da Roit, L Bologna, C Ferrara, JH Leusen, A Rambaldi, C Klein, ...
Blood, The Journal of the American Society of Hematology 122 (20), 3482-3491, 2013
2162013
Mac-1 (CD11b/CD18) is essential for Fc receptor–mediated neutrophil cytotoxicity and immunologic synapse formation
AB van Spriel, JHW Leusen, M van Egmond, HBPM Dijkman, ...
Blood, The Journal of the American Society of Hematology 97 (8), 2478-2486, 2001
2112001
The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcγ receptor–mediated cross-linking
MB Overdijk, JHM Jansen, M Nederend, JJL van Bueren, RWJ Groen, ...
The Journal of Immunology 197 (3), 807-813, 2016
1922016
Crosstalk between human IgG isotypes and murine effector cells
MB Overdijk, S Verploegen, AO Buijsse, T Vink, JHW Leusen, WK Bleeker, ...
The Journal of Immunology 189 (7), 3430-3438, 2012
1802012
Functional characteristics of the high affinity IgG receptor, FcγRI
CE van der Poel, RM Spaapen, JGJ van de Winkel, JHW Leusen
The Journal of Immunology 186 (5), 2699-2704, 2011
1622011
Interactions between the components of the human NADPH oxidase: intrigues in the phox family
JHW Leusen, AJ Verhoeven, D Roos
Journal of Laboratory and Clinical Medicine 128 (5), 461-476, 1996
1501996
In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling
S de Haij, JHM Jansen, P Boross, FJ Beurskens, JE Bakema, DL Bos, ...
Cancer research 70 (8), 3209-3217, 2010
1302010
156Pro--> Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and…
JH Leusen, BG Bolscher, PM Hilarius, RS Weening, W Kaulfersch, ...
The Journal of experimental medicine 180 (6), 2329-2334, 1994
1281994
The high-affinity IgG receptor, FcγRI, plays a central role in antibody therapy of experimental melanoma
L Bevaart, MJH Jansen, MJ van Vugt, JS Verbeek, JGJ van de Winkel, ...
Cancer research 66 (3), 1261-1264, 2006
1262006
Neutrophils kill antibody-opsonized cancer cells by trogoptosis
HL Matlung, L Babes, XW Zhao, M van Houdt, LW Treffers, DJ van Rees, ...
Cell Reports 23 (13), 3946-3959. e6, 2018
1132018
Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden
A hlin, M De Boer, D Roos, J Leusen, CIE Smith, U Sundin, H Rabbani, ...
Acta paediatrica 84 (12), 1386-1394, 1995
1131995
A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.
JH Leusen, M de Boer, BG Bolscher, PM Hilarius, RS Weening, HD Ochs, ...
The Journal of clinical investigation 93 (5), 2120-2126, 1994
1121994
The importance of human FcγRI in mediating protection to malaria
RS McIntosh, J Shi, RM Jennings, JC Chappel, TF de Koning-Ward, ...
PLoS pathogens 3 (5), e72, 2007
1112007
Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease.
JH Leusen, A de Klein, PM Hilarius, A Ahlin, J Palmblad, CI Smith, ...
The Journal of experimental medicine 184 (4), 1243-1249, 1996
941996
Plant-derived anti-Lewis Y mAb exhibits biological activities for efficient immunotherapy against human cancer cells
R Brodzik, M Glogowska, K Bandurska, M Okulicz, D Deka, K Ko, ...
Proceedings of the National Academy of Sciences 103 (23), 8804-8809, 2006
922006
Cytolytic mechanisms and expression of activation-regulating receptors on effector-type CD8+ CD45RA+ CD27− human T cells
PA Baars, LMR do Couto, JHW Leusen, B Hooibrink, TW Kuijpers, ...
the Journal of Immunology 165 (4), 1910-1917, 2000
912000
Interactions between the components of the human NADPH oxidase: a review about the intrigues in the phox family
JHW Leusen, AJ Verhoeven, D Roos
Front Biosci 1, d72-d90, 1996
901996
IgA EGFR antibodies mediate tumour killing in vivo
P Boross, S Lohse, M Nederend, JHM Jansen, G van Tetering, M Dechant, ...
EMBO molecular medicine 5 (8), 1213-1226, 2013
892013
The FcγRIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR γ-chain
MJ van Vugt, MJ Kleijmeer, T Keler, I Zeelenberg, MA van Dijk, ...
Blood, The Journal of the American Society of Hematology 94 (2), 808-817, 1999
891999
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Artikelen 1–20