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Ying Lai
Ying Lai
Sichuan University
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ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
J Diao, R Liu, Y Rong, M Zhao, J Zhang, Y Lai, Q Zhou, LM Wilz, J Li, ...
Nature 520 (7548), 563-566, 2015
5752015
Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
BK Choi, MG Choi, JY Kim, Y Yang, Y Lai, DH Kweon, NK Lee, YK Shin
Proceedings of the National Academy of Sciences 110 (10), 4087-4092, 2013
3452013
Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis
Q Zhou, Y Lai, T Bacaj, M Zhao, AY Lyubimov, M Uervirojnangkoorn, ...
Nature 525 (7567), 62-67, 2015
3152015
Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18
Y Lai, UB Choi, J Leitz, HJ Rhee, C Lee, B Altas, M Zhao, RA Pfuetzner, ...
Neuron 95 (3), 591-607. e10, 2017
2182017
Molecular mechanisms of fast neurotransmitter release
AT Brunger, UB Choi, Y Lai, J Leitz, Q Zhou
Annual review of biophysics 47, 469-497, 2018
1362018
SNARE-mediated membrane fusion in autophagy
Y Wang, L Li, C Hou, Y Lai, J Long, J Liu, Q Zhong, J Diao
Seminars in cell & developmental biology 60, 97-104, 2016
1332016
Versatile structures of α-synuclein
C Wang, C Zhao, D Li, Z Tian, Y Lai, J Diao, C Liu
Frontiers in molecular neuroscience 9, 48, 2016
1212016
Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1
Y Lai, J Diao, Y Liu, Y Ishitsuka, Z Su, K Schulten, T Ha, YK Shin
Proceedings of the National Academy of Sciences 110 (4), 1333-1338, 2013
1062013
Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms
Y Lai, J Diao, DJ Cipriano, Y Zhang, RA Pfuetzner, MS Padolina, ...
Elife 3, e03756, 2014
1012014
Nonaggregated α-synuclein influences SNARE-dependent vesicle docking via membrane binding
Y Lai, S Kim, J Varkey, X Lou, JK Song, J Diao, R Langen, YK Shin
Biochemistry 53 (24), 3889-3896, 2014
1012014
The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability
J Du, X Cai, J Yao, X Ding, Q Wu, S Pei, K Jiang, Y Zhang, W Wang, Y Shi, ...
Oncogene 27 (29), 4107-4114, 2008
922008
A single-vesicle content mixing assay for SNARE-mediated membrane fusion
J Diao, Z Su, Y Ishitsuka, B Lu, KS Lee, Y Lai, YK Shin, T Ha
Nature communications 1 (1), 54, 2010
892010
Solution single‐vesicle assay reveals PIP2‐mediated sequential actions of synaptotagmin‐1 on SNAREs
JY Kim, BK Choi, MG Choi, SA Kim, Y Lai, YK Shin, NK Lee
The EMBO journal 31 (9), 2144-2155, 2012
872012
The pre-synaptic fusion machinery
AT Brunger, UB Choi, Y Lai, J Leitz, KI White, Q Zhou
Current opinion in structural biology 54, 179-188, 2019
842019
C-terminal domain of mammalian complexin-1 localizes to highly curved membranes
J Gong, Y Lai, X Li, M Wang, J Leitz, Y Hu, Y Zhang, UB Choi, D Cipriano, ...
Proceedings of the National Academy of Sciences 113 (47), E7590-E7599, 2016
642016
Morphologies of synaptic protein membrane fusion interfaces
P Gipson, Y Fukuda, R Danev, Y Lai, DH Chen, W Baumeister, ...
Proceedings of the National Academy of Sciences 114 (34), 9110-9115, 2017
552017
N-terminal domain of complexin independently activates calcium-triggered fusion
Y Lai, UB Choi, Y Zhang, M Zhao, RA Pfuetzner, AL Wang, J Diao, ...
Proceedings of the National Academy of Sciences 113 (32), E4698-E4707, 2016
522016
Ca2+-triggered synaptic vesicle fusion initiated by release of inhibition
AT Brunger, J Leitz, Q Zhou, UB Choi, Y Lai
Trends in cell biology 28 (8), 631-645, 2018
512018
Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion
S Malmersjö, S Di Palma, J Diao, Y Lai, RA Pfuetzner, AL Wang, ...
The EMBO journal 35 (16), 1810-1821, 2016
462016
Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides
Y Lai, G Fois, JR Flores, MJ Tuvim, Q Zhou, K Yang, J Leitz, J Peters, ...
Nature 603 (7903), 949-956, 2022
452022
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