Lara Bossini-Castillo
Lara Bossini-Castillo
Associate Professor. Department of Genetics, University of Granada, Spain.
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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ...
Nature genetics 49 (3), 416-425, 2017
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis
MD Mayes, L Bossini-Castillo, O Gorlova, JE Martin, X Zhou, WV Chen, ...
The American Journal of Human Genetics 94 (1), 47-61, 2014
Gene expression variability across cells and species shapes innate immunity
T Hagai, X Chen, RJ Miragaia, R Rostom, T Gomes, N Kunowska, ...
Nature 563 (7730), 197-202, 2018
A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.
FD Carmona, SL Mackie, JE Martín, JC Taylor, A Vaglio, S Eyre, ...
American Journal of Human Genetics 96 (4), 565-80, 2015
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
E López-Isac, M Acosta-Herrera, M Kerick, S Assassi, AT Satpathy, ...
Nature communications 10 (1), 4955, 2019
A rare polymorphism in the gene for Toll‐like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators
JCA Broen, L Bossini‐Castillo, L Van Bon, MC Vonk, H Knaapen, ...
Arthritis & Rheumatism 64 (1), 264-271, 2012
HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping
JL Guéant, A Romano, JA Cornejo-Garcia, A Oussalah, C Chery, ...
Journal of Allergy and Clinical Immunology 135 (1), 253-259. e10, 2015
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
B Soskic, E Cano-Gamez, DJ Smyth, WC Rowan, N Nakic, ...
Nature genetics 51 (10), 1486-1493, 2019
IRF5 polymorphism predicts prognosis in patients with systemic sclerosis
R Sharif, MD Mayes, FK Tan, OY Gorlova, LK Hummers, AA Shah, ...
Annals of the rheumatic diseases 71 (7), 1197-1202, 2012
A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations
L Bossini-Castillo, JE Martin, J Broen, O Gorlova, CP Simeón, L Beretta, ...
Human molecular genetics 21 (4), 926-933, 2012
A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
L Bossini-Castillo, C De Kovel, H Kallberg, R van‘t Slot, A Italiaander, ...
Annals of the rheumatic diseases 74 (3), e15-e15, 2015
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
JG Pouget, ...
Human Molecular Genetics 28 (20), 3498-3513, 2019
Immunogenetics of systemic sclerosis: defining heritability, functional variants and shared-autoimmunity pathways
L Bossini-Castillo, E López-Isac, J Martín
Journal of autoimmunity 64, 53-65, 2015
A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort
L Bossini-Castillo, JCA Broen, CP Simeon, L Beretta, MC Vonk, ...
Annals of the rheumatic diseases 70 (4), 638-641, 2011
Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study
L Bossini-Castillo, JE Martin, J Broen, CP Simeon, L Beretta, OY Gorlova, ...
Annals of the rheumatic diseases 72 (4), 602-607, 2013
Unraveling the genetic component of systemic sclerosis
JE Martín, L Bossini-Castillo, J Martín
Human genetics 131, 1023-1037, 2012
Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
B Soskic, E Cano-Gamez, DJ Smyth, K Ambridge, Z Ke, JC Matte, ...
Nature genetics 54 (6), 817-826, 2022
Association of MicroRNA‐618 expression with altered frequency and activation of plasmacytoid dendritic cells in patients with systemic sclerosis
M Rossato, AJ Affandi, S Thordardottir, CGK Wichers, M Cossu, ...
Arthritis & rheumatology 69 (9), 1891-1902, 2017
Genetics of systemic sclerosis
L Bossini-Castillo, E López-Isac, MD Mayes, J Martín
Seminars in immunopathology 37, 443-451, 2015
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells
R Nasrallah, CJ Imianowski, L Bossini-Castillo, FM Grant, M Dogan, ...
Nature 583 (7816), 447-452, 2020
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