| Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ... Cell 182 (5), 1295-1310. e20, 2020 | 1846 | 2020 |
| Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ... Cell host & microbe, 2021 | 1175 | 2021 |
| Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ... Cell host & microbe 29 (1), 44-57. e9, 2021 | 1041 | 2021 |
| Prospective mapping of viral mutations that escape antibodies used to treat COVID-19 TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ... Science 371 (6531), 850-854, 2021 | 733 | 2021 |
| Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016 TN Starr, AJ Greaney, AS Dingens, JD Bloom Cell Reports Medicine 2 (4), 100255, 2021 | 466 | 2021 |
| Epistasis in protein evolution TN Starr, JW Thornton Protein Science, 2016 | 455 | 2016 |
| SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ... Nature 597 (7874), 97-102, 2021 | 393 | 2021 |
| Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies AJ Greaney, TN Starr, CO Barnes, Y Weisblum, F Schmidt, M Caskey, ... Nature Communications 12 (1), 1-14, 2021 | 382* | 2021 |
| Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ... Nature Microbiology 6 (10), 1233-1244, 2021 | 363* | 2021 |
| Broad sarbecovirus neutralization by a human monoclonal antibody MA Tortorici, N Czudnochowski, TN Starr, R Marzi, AC Walls, F Zatta, ... Nature 597 (7874), 103-108, 2021 | 215 | 2021 |
| Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection AJ Greaney, AN Loes, LE Gentles, KHD Crawford, TN Starr, KD Malone, ... Science translational medicine 13 (600), eabi9915, 2021 | 209 | 2021 |
| Alternative evolutionary histories in the sequence space of an ancient protein TN Starr, LK Picton, JW Thornton Nature 549 (7672), 409-413, 2017 | 186 | 2017 |
| Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution TN Starr, AJ Greaney, WW Hannon, AN Loes, K Hauser, JR Dillen, E Ferri, ... Science 377 (6604), 420-424, 2022 | 150 | 2022 |
| Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ... Cell 184 (21), 5432-5447. e16, 2021 | 142 | 2021 |
| Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models AA Cohen, N van Doremalen, AJ Greaney, H Andersen, A Sharma, ... Science 377 (6606), eabq0839, 2022 | 128 | 2022 |
| ACE2 binding is an ancestral and evolvable trait of sarbecoviruses TN Starr, SK Zepeda, AC Walls, AJ Greaney, S Alkhovsky, D Veesler, ... Nature 603 (7903), 913-918, 2022 | 124 | 2022 |
| Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function P Mishra, JM Flynn, TN Starr, DNA Bolon Cell Reports 15 (3), 588-598, 2016 | 114 | 2016 |
| Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry YJ Park, A De Marco, TN Starr, Z Liu, D Pinto, AC Walls, F Zatta, ... Science 375 (6579), 449-454, 2022 | 106 | 2022 |
| Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA. 1 that likely impact Spike function DP Martin, S Lytras, AG Lucaci, W Maier, B Grüning, SD Shank, S Weaver, ... Molecular Biology and Evolution, 2022 | 100* | 2022 |
| Pervasive contingency and entrenchment in a billion years of Hsp90 evolution TN Starr, JM Flynn, P Mishra, DNA Bolon, JW Thornton Proceedings of the National Academy of Sciences 115 (17), 4453-4458, 2018 | 100 | 2018 |
Jesse D. BloomFred Hutch Cancer Center; University of Washington; Howard Hughes Medical InstituteVerified email at fredhutch.org
