Tyler Starr
Tyler Starr
Washington Research Foundation and HHMI Damon Runyon Fellow, Fred Hutchinson Cancer Research Center
Verified email at fredhutch.org
Cited by
Cited by
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
Cell 182 (5), 1295-1310. e20, 2020
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ...
Cell host & microbe, 2021
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
Epistasis in protein evolution
TN Starr, JW Thornton
Protein Science, 2016
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ...
Science 371 (6531), 850-854, 2021
Alternative evolutionary histories in the sequence space of an ancient protein
TN Starr, LK Picton, JW Thornton
Nature 549 (7672), 409-413, 2017
Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function
P Mishra, JM Flynn, TN Starr, DNA Bolon
Cell Reports 15 (3), 588-598, 2016
Pervasive contingency and entrenchment in a billion years of Hsp90 evolution
TN Starr, JM Flynn, P Mishra, DNA Bolon, JW Thornton
Proceedings of the National Academy of Sciences 115 (17), 4453-4458, 2018
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
TN Starr, AJ Greaney, AS Dingens, JD Bloom
Cell Reports Medicine 2 (4), 100255, 2021
Asymmetric hybridization and gene flow between Joshua trees (Agavaceae: Yucca) reflect differences in pollinator host specificity
TN Starr, KE Gadek, JB Yoder, R Flatz, CI Smith
Molecular ecology 22 (2), 437-449, 2013
Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail
J Dong, S Zost, A Greaney, TN Starr, AS Dingens, EC Chen, R Chen, ...
bioRxiv, 2021
Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies
AJ Greaney, TN Starr, CO Barnes, Y Weisblum, F Schmidt, M Caskey, ...
bioRxiv, 2021
Exploring protein sequence-function landscapes
TN Starr, JW Thornton
Nature Biotechnology 35 (2), 125-126, 2017
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
TN Starr, N Czudnochowski, F Zatta, YJ Park, Z Liu, A Addetia, D Pinto, ...
bioRxiv, 2021
Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody
MA Tortorici, N Czudnochowski, TN Starr, R Marzi, AC Walls, F Zatta, ...
bioRxiv, 2021
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection
AJ Greaney, AN Loes, LE Gentles, KHD Crawford, TN Starr, KD Malone, ...
Science Translational Medicine, 2021
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, MN Pham, A Schaefer, A Greaney, ...
bioRxiv, 2021
Stabilization of the SARS-CoV-2 Spike receptor-binding domain using deep mutational scanning and structure-based design
D Ellis, N Brunette, KHD Crawford, AC Walls, MN Pham, C Chen, ...
bioRxiv, 2021
Epistasis, Contingency, and Evolvability in the Sequence Space of Ancient Proteins
TN Starr
The University of Chicago, 2018
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