Giuseppe Legname
Giuseppe Legname
Professor of Biochemistry - SISSA
Verified email at - Homepage
Cited by
Cited by
Synthetic mammalian prions
G Legname, IV Baskakov, HOB Nguyen, D Riesner, FE Cohen, ...
Science 305 (5684), 673-676, 2004
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
D Peretz, RA Williamson, K Kaneko, J Vergara, E Leclerc, G Schmitt-Ulms, ...
Nature 412 (6848), 739-743, 2001
Pathway complexity of prion protein assembly into amyloid
IV Baskakov, G Legname, MA Baldwin, SB Prusiner, FE Cohen
Journal of Biological Chemistry 277 (24), 21140-21148, 2002
Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein
G Schmitt-Ulms, G Legname, MA Baldwin, HL Ball, N Bradon, PJ Bosque, ...
Journal of molecular biology 314 (5), 1209-1225, 2001
Copper coordination in the full-length, recombinant prion protein
CS Burns, E Aronoff-Spencer, G Legname, SB Prusiner, WE Antholine, ...
Biochemistry 42 (22), 6794-6803, 2003
A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration
K Watase, EJ Weeber, B Xu, B Antalffy, L Yuva-Paylor, K Hashimoto, ...
Neuron 34 (6), 905-919, 2002
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice
JG Safar, M Scott, J Monaghan, C Deering, S Didorenko, J Vergara, ...
Nature biotechnology 20 (11), 1147-1150, 2002
Folding of prion protein to its native α-helical conformation is under kinetic control
IV Baskakov, G Legname, SB Prusiner, FE Cohen
Journal of Biological Chemistry 276 (23), 19687-19690, 2001
A change in the conformation of prions accompanies the emergence of a new prion strain
D Peretz, RA Williamson, G Legname, Y Matsunaga, J Vergara, ...
Neuron 34 (6), 921-932, 2002
Cytosolic prion protein in neurons
A Mironov, D Latawiec, H Wille, E Bouzamondo-Bernstein, G Legname, ...
Journal of Neuroscience 23 (18), 7183-7193, 2003
The influence of the src‐family kinases, Lck and Fyn, on T cell differentiation, survival and activation
R Zamoyska, A Basson, A Filby, G Legname, M Lovatt, B Seddon
Immunological reviews 191 (1), 107-118, 2003
Prion detection by an amyloid seeding assay
DW Colby, Q Zhang, S Wang, D Groth, G Legname, D Riesner, ...
Proceedings of the National Academy of Sciences 104 (52), 20914-20919, 2007
Prions in skeletal muscle
PJ Bosque, C Ryou, G Telling, D Peretz, G Legname, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 99 (6), 3812-3817, 2002
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes
G Legname, HOB Nguyen, D Peretz, FE Cohen, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 103 (50), 19105-19110, 2006
Strain-specified characteristics of mouse synthetic prions
G Legname, HOB Nguyen, IV Baskakov, FE Cohen, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 102 (6), 2168-2173, 2005
Design and construction of diverse mammalian prion strains
DW Colby, K Giles, G Legname, H Wille, IV Baskakov, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 106 (48), 20417-20422, 2009
Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro
J Kanaani, SB Prusiner, J Diacovo, S Baekkeskov, G Legname
Journal of neurochemistry 95 (5), 1373-1386, 2005
Locally Disordered Conformer of the Hamster Prion Protein:  A Crucial Intermediate to PrPSc?
K Kuwata, H Li, H Yamada, G Legname, SB Prusiner, K Akasaka, ...
Biochemistry 41 (41), 12277-12283, 2002
Doppel-induced cerebellar degeneration in transgenic mice
RC Moore, P Mastrangelo, E Bouzamondo, C Heinrich, G Legname, ...
Proceedings of the National Academy of Sciences 98 (26), 15288-15293, 2001
Copper-catalyzed oxidation of the recombinant SHa (29–231) prion protein
JR Requena, D Groth, G Legname, ER Stadtman, SB Prusiner, RL Levine
Proceedings of the National Academy of Sciences 98 (13), 7170-7175, 2001
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