| The same, only different–DNA damage checkpoints and their reversal throughout the cell cycle IA Shaltiel, L Krenning, W Bruinsma, RH Medema Journal of cell science 128 (4), 607-620, 2015 | 368 | 2015 |
| Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 68 (1), 210-223. e6, 2017 | 223 | 2017 |
| Transient activation of p53 in G2 phase is sufficient to induce senescence L Krenning, FM Feringa, IA Shaltiel, J van den Berg, RH Medema Molecular cell 55 (1), 59-72, 2014 | 209 | 2014 |
| Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore J Espeut, DK Cheerambathur, L Krenning, K Oegema, A Desai Journal of Cell Biology 196 (4), 469-482, 2012 | 168 | 2012 |
| Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies N Battich, J Beumer, B De Barbanson, L Krenning, CS Baron, ... Science 367 (6482), 1151-1156, 2020 | 99 | 2020 |
| Life or death after a break: what determines the choice? L Krenning, J van den Berg, RH Medema Molecular cell 76 (2), 346-358, 2019 | 84 | 2019 |
| Chromosomes trapped in micronuclei are liable to segregation errors M Soto, I Garcia-Santisteban, L Krenning, RH Medema, JA Raaijmakers Journal of cell science 131 (13), jcs214742, 2018 | 83 | 2018 |
| Recovery from a DNA‐damage‐induced G2 arrest requires Cdk‐dependent activation of FoxM1 M Alvarez‐Fernández, VA Halim, L Krenning, M Aprelia, S Mohammed, ... EMBO reports 11 (6), 452-458, 2010 | 65 | 2010 |
| Persistent repair intermediates induce senescence FM Feringa, JA Raaijmakers, MA Hadders, C Vaarting, L Macurek, ... Nature Communications 9 (1), 3923, 2018 | 57 | 2018 |
| Hypersensitivity to DNA damage in antephase as a safeguard for genome stability FM Feringa, L Krenning, A Koch, J Van Den Berg, B Van Den Broek, ... Nature Communications 7 (1), 12618, 2016 | 31 | 2016 |
| Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 79 (1), 191-198. e3, 2020 | 29 | 2020 |
| Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during the mitosis-to-G1 phase transition L Krenning, S Sonneveld, ME Tanenbaum Elife 11, e71356, 2022 | 23* | 2022 |
| Resistance of hypoxic cells to ionizing radiation is mediated in part via hypoxia-induced quiescence A Menegakis, R Klompmaker, C Vennin, A Arbusà, M Damen, ... Cells 10 (3), 610, 2021 | 23 | 2021 |
| A FOXO-dependent replication checkpoint restricts proliferation of damaged cells M Hornsveld, FM Feringa, L Krenning, J van den Berg, LMM Smits, ... Cell Reports 34 (4), 2021 | 12 | 2021 |
| Double-strand break toxicity is chromatin context independent A Friskes, L Koob, L Krenning, TM Severson, ES Koeleman, X Vergara, ... Nucleic Acids Research 50 (17), 9930-9947, 2022 | 11 | 2022 |
| Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity Z Pogacar, JL Johnson, L Krenning, G De Conti, F Jochems, C Lieftink, ... Plos one 17 (9), e0273182, 2022 | 9 | 2022 |
| Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells I García-Santisteban, A Llopis, L Krenning, J Vallejo-Rodríguez, ... BMC biology 19, 1-13, 2021 | 9 | 2021 |
| DNA end-resection in highly accessible chromatin produces a toxic break J van den Berg, SEP Joosten, YS Kim, AG Manjón, L Krenning, L Koob, ... BioRxiv, 691857, 2019 | 9 | 2019 |
| Enter the nucleus to exit the cycle: Comment on: Müllers E, et al. Cell Cycle 2014; 13: 2733-43; http://dx. doi. org/10.4161/15384101.2015. 945831 L Krenning, RH Medema Cell Cycle 13 (17), 2651-52, 2014 | 4 | 2014 |
| Optimized Cas9 expression improves performance of large-scale CRISPR screening JMF Neto, K Jastrzebski, C Lieftink, L Krenning, M Dias, B Morris, ... bioRxiv, 2021 | 2 | 2021 |
Rene H. MedemaThe Netherlands Cancer InstituteVerified email at nki.nl
