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Lennart Mucke, M.D.
Lennart Mucke, M.D.
Director, Gladstone Institute of Neurological Disease; Professor of Neurology and Neuroscience
Verified email at gladstone.ucsf.edu - Homepage
Title
Cited by
Cited by
Year
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
D Games, D Adams, R Alessandrini, R Barbour, P Borthelette, ...
Nature 373 (6514), 523-527, 1995
35251995
High-level neuronal expression of Aβ1–42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation
L Mucke, E Masliah, GQ Yu, M Mallory, EM Rockenstein, G Tatsuno, K Hu, ...
Journal of Neuroscience 20 (11), 4050-4058, 2000
23372000
Reducing endogenous tau ameliorates amyloid ß-induced deficits in an Alzheimer's disease mouse model
ED Roberson, K Scearce-Levie, JJ Palop, F Yan, IH Cheng, T Wu, ...
Science 316 (5825), 750-754, 2007
23132007
Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders
E Masliah, E Rockenstein, I Veinbergs, M Mallory, M Hashimoto, ...
Science 287 (5456), 1265-1269, 2000
22732000
Alzheimer mechanisms and therapeutic strategies
Y Huang, L Mucke
Cell 148 (6), 1204-1222, 2012
21362012
Molecular profile of reactive astrocytes—implications for their role in neurologic disease
M Eddleston, L Mucke
Neuroscience 54 (1), 15-36, 1993
18801993
Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
JJ Palop, L Mucke
Nature neuroscience 13 (7), 812-818, 2010
18462010
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
JJ Palop, J Chin, ED Roberson, J Wang, MT Thwin, N Bien-Ly, J Yoo, ...
Neuron 55 (5), 697-711, 2007
16922007
Inflammation in neurodegenerative disease—a double-edged sword
T Wyss-Coray, L Mucke
Neuron 35 (3), 419-432, 2002
15262002
Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models
AY Hsia, E Masliah, L McConlogue, GQ Yu, G Tatsuno, K Hu, ...
Proceedings of the National Academy of Sciences 96 (6), 3228-3233, 1999
14681999
Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice
TG Bush, N Puvanachandra, CH Horner, A Polito, T Ostenfeld, ...
Neuron 23 (2), 297-308, 1999
13601999
Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.
IL Campbell, CR Abraham, E Masliah, P Kemper, JD Inglis, MB Oldstone, ...
Proceedings of the National Academy of Sciences 90 (21), 10061-10065, 1993
12411993
Neurotoxicity of amyloid β-protein: synaptic and network dysfunction
L Mucke, DJ Selkoe
Cold Spring Harbor perspectives in medicine 2 (7), a006338, 2012
11572012
Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model
L Verret, EO Mann, GB Hang, AMI Barth, I Cobos, K Ho, N Devidze, ...
Cell 149 (3), 708-721, 2012
11342012
The many faces of tau
M Morris, S Maeda, K Vossel, L Mucke
Neuron 70 (3), 410-426, 2011
10292011
SIRT1 protects against microglia-dependent amyloid-β toxicity through inhibiting NF-κB signaling
J Chen, Y Zhou, S Mueller-Steiner, LF Chen, H Kwon, S Yi, L Mucke, ...
Journal of Biological Chemistry 280 (48), 40364-40374, 2005
8852005
Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice
SM Toggas, E Masliah, EM Rockenstein, GF Rail, CR Abraham, L Mucke
Nature 367 (6459), 188-193, 1994
8081994
Network abnormalities and interneuron dysfunction in Alzheimer disease
JJ Palop, L Mucke
Nature Reviews Neuroscience 17 (12), 777-792, 2016
8052016
Epilepsy and cognitive impairments in Alzheimer disease
JJ Palop, L Mucke
Archives of neurology 66 (4), 435-440, 2009
7722009
A network dysfunction perspective on neurodegenerative diseases
JJ Palop, J Chin, L Mucke
Nature 443 (7113), 768-773, 2006
7602006
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