J.K. Kruit
J.K. Kruit
Unknown affiliation
Verified email at rug.nl
Cited by
Cited by
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo
LR Brunham, JK Kruit, J Iqbal, C Fievet, JM Timmins, TD Pape, ...
The Journal of clinical investigation 116 (4), 1052-1062, 2006
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ...
Nature medicine 13 (3), 340-347, 2007
Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice
R Out, M Hoekstra, RB Hildebrand, JK Kruit, I Meurs, Z Li, F Kuipers, ...
Arteriosclerosis, thrombosis, and vascular biology 26 (10), 2295-2300, 2006
Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1
JN Van Der Veen, JK Kruit, R Havinga, JFW Baller, G Chimini, S Lestavel, ...
Journal of lipid research 46 (3), 526-534, 2005
Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice
JK Kruit, T Plösch, R Havinga, R Boverhof, PHE Groot, AK Groen, ...
Gastroenterology 128 (1), 147-156, 2005
Cholesterol in islet dysfunction and type 2 diabetes
LR Brunham, JK Kruit, CB Verchere, MR Hayden
The Journal of clinical investigation 118 (2), 403-408, 2008
Emerging roles of the intestine in control of cholesterol metabolism
JK Kruit, AK Groen, TJ van Berkel, F Kuipers
World journal of gastroenterology: WJG 12 (40), 6429, 2006
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans
V Acuña-Alonzo, T Flores-Dorantes, JK Kruit, T Villarreal-Molina, ...
Human Molecular Genetics 19 (14), 2877-2885, 2010
HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus
JK Kruit, LR Brunham, CB Verchere, MR Hayden
Current opinion in lipidology 21 (3), 178-185, 2010
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function
JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ...
Journal of Neuroscience 29 (11), 3579-3589, 2009
Carriers of loss-of-function mutations in ABCA1 display pancreatic β-cell dysfunction
M Vergeer, LR Brunham, J Koetsveld, JK Kruit, CB Verchere, ...
Diabetes Care 33 (4), 869-874, 2010
Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels
LR Brunham, JK Kruit, TD Pape, JS Parks, F Kuipers, MR Hayden
Circulation research 99 (7), 672-674, 2006
Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function …
JK Kruit, PHC Kremer, L Dai, R Tang, P Ruddle, W de Haan, LR Brunham, ...
Diabetologia 53 (6), 1110-1119, 2010
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter
T Plösch, JK Kruit, VW Bloks, NCA Huijkman, R Havinga, GS Duchateau, ...
The Journal of nutrition 136 (8), 2135-2140, 2006
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function
JK Kruit, N Wijesekara, C Westwell-Roper, T Vanmierlo, W De Haan, ...
Diabetes 61 (3), 659-664, 2012
Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules
JK Kruit, N Wijesekara, JEM Fox, XQ Dai, LR Brunham, GJ Searle, ...
Diabetes 60 (12), 3186-3196, 2011
Cholesterol in β-cell dysfunction: the emerging connection between HDL cholesterol and Type 2 diabetes
LR Brunham, JK Kruit, MR Hayden, CB Verchere
Current diabetes reports 10 (1), 55-60, 2010
Lymphocyte-derived exosomal micrornas promote pancreatic β cell death and may contribute to type 1 diabetes development
C Guay, JK Kruit, S Rome, V Menoud, NL Mulder, A Jurdzinski, ...
Cell metabolism 29 (2), 348-361. e6, 2019
ABCA1 influences neuroinflammation and neuronal death
JM Karasinska, W de Haan, S Franciosi, P Ruddle, J Fan, JK Kruit, ...
Neurobiology of disease 54, 445-455, 2013
Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia
JK Kruit, AL Drayer, VW Bloks, N Blom, SG Olthof, PJJ Sauer, G De Haan, ...
Journal of Biological Chemistry 283 (10), 6281-6287, 2008
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