Alexandre Trindade
Alexandre Trindade
Assistant Professor, Egas Moniz, Cooperativa de Ensino Superior
Geverifieerd e-mailadres voor egasmoniz.edu.pt
Geciteerd door
Geciteerd door
Dosage-sensitive requirement for mouse Dll4 in artery development
A Duarte, M Hirashima, R Benedito, A Trindade, P Diniz, E Bekman, ...
Genes & development 18 (20), 2474-2478, 2004
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion
JS Scehnet, W Jiang, S Ram Kumar, V Krasnoperov, A Trindade, ...
Blood, The Journal of the American Society of Hematology 109 (11), 4753-4760, 2007
Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos
A Trindade, S Ram Kumar, JS Scehnet, L Lopes-da-Costa, J Becker, ...
Blood, The Journal of the American Society of Hematology 112 (5), 1720-1729, 2008
Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1
AR Pedrosa, A Trindade, AC Fernandes, C Carvalho, J Gigante, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (5), 1134-1146, 2015
Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis
D Djokovic, A Trindade, J Gigante, M Badenes, L Silva, R Liu, X Li, ...
BMC cancer 10 (1), 1-12, 2010
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice
PM Rodrigues, MB Afonso, AL Simão, CC Carvalho, A Trindade, A Duarte, ...
Cell death & disease 8 (4), e2748-e2748, 2017
Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli
R Benedito, A Trindade, M Hirashima, D Henrique, LL da Costa, ...
BMC developmental biology 8, 1-15, 2008
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models
B Cristofaro, Y Shi, M Faria, S Suchting, AS Leroyer, A Trindade, A Duarte, ...
Development 140 (8), 1720-1729, 2013
Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions
AR Pedrosa, A Trindade, C Carvalho, J Graça, S Carvalho, MC Peleteiro, ...
Oncotarget 6 (27), 24404, 2015
Notch1 is pan-endothelial at the onset of flow and regulated by flow
ED Jahnsen, A Trindade, HC Zaun, S Lehoux, A Duarte, EAV Jones
PloS one 10 (4), e0122622, 2015
Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle
D Murta, M Batista, E Silva, A Trindade, D Henrique, A Duarte, ...
PloS one 8 (8), e72767, 2013
Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesis
A Trindade, D Djokovic, J Gigante, M Badenes, AR Pedrosa, ...
PloS one 7 (1), e29863, 2012
In Vivo Notch Signaling Blockade Induces Abnormal Spermatogenesis in the Mouse
D Murta, M Batista, A Trindade, E Silva, D Henrique, A Duarte, ...
PloS one 9 (11), e113365, 2014
Notch signaling dynamics in the adult healthy prostate and in prostatic tumor development
AR Pedrosa, JL Graça, S Carvalho, MC Peleteiro, A Duarte, A Trindade
The Prostate 76 (1), 80-96, 2016
Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo
A Trindade, D Djokovic, J Gigante, L Mendonça, A Duarte
BMC cancer 17 (1), 1-13, 2017
Differential expression of Notch component and effector genes during ovarian follicle and corpus luteum development during the oestrous cycle
D Murta, M Batista, E Silva, A Trindade, L Mateus, A Duarte, ...
Reproduction, Fertility and Development 27 (7), 1038-1048, 2015
Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition and reduction of cancer stem cells and …
L Mendonça, A Trindade, C Carvalho, J Correia, M Badenes, J Gigante, ...
Clinical & experimental metastasis 36, 365-380, 2019
Notch signaling in the epididymal epithelium regulates sperm motility and is transferred at a distance within epididymosomes
D Murta, M Batista, E Silva, A Trindade, D Henrique, A Duarte, ...
Andrology 4 (2), 314-327, 2016
Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues
R Liu, A Trindade, Z Sun, R Kumar, FA Weaver, V Krasnoperov, K Naga, ...
Biochemical and Biophysical Research Communications 418 (1), 173-179, 2012
Bone marrow-derived endothelial progenitors expressing Delta-like 4 (Dll4) regulate tumor angiogenesis
C Real, L Remedio, F Caiado, C Igreja, C Borges, A Trindade, ...
PLoS One 6 (4), e18323, 2011
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