Dosage-sensitive requirement for mouse Dll4 in artery development A Duarte, M Hirashima, R Benedito, A Trindade, P Diniz, E Bekman, ... Genes & development 18 (20), 2474-2478, 2004 | 734 | 2004 |
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion JS Scehnet, W Jiang, S Ram Kumar, V Krasnoperov, A Trindade, ... Blood, The Journal of the American Society of Hematology 109 (11), 4753-4760, 2007 | 348 | 2007 |
Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos A Trindade, S Ram Kumar, JS Scehnet, L Lopes-da-Costa, J Becker, ... Blood, The Journal of the American Society of Hematology 112 (5), 1720-1729, 2008 | 170 | 2008 |
Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1 AR Pedrosa, A Trindade, AC Fernandes, C Carvalho, J Gigante, ... Arteriosclerosis, thrombosis, and vascular biology 35 (5), 1134-1146, 2015 | 141 | 2015 |
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice PM Rodrigues, MB Afonso, AL Simão, CC Carvalho, A Trindade, A Duarte, ... Cell death & disease 8 (4), e2748-e2748, 2017 | 129 | 2017 |
Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis D Djokovic, A Trindade, J Gigante, M Badenes, L Silva, R Liu, X Li, ... BMC cancer 10, 1-12, 2010 | 121 | 2010 |
Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli R Benedito, A Trindade, M Hirashima, D Henrique, LL Da Costa, ... BMC developmental biology 8, 1-15, 2008 | 98 | 2008 |
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models B Cristofaro, Y Shi, M Faria, S Suchting, AS Leroyer, A Trindade, A Duarte, ... Development 140 (8), 1720-1729, 2013 | 83 | 2013 |
Notch1 is pan-endothelial at the onset of flow and regulated by flow ED Jahnsen, A Trindade, HC Zaun, S Lehoux, A Duarte, EAV Jones PloS one 10 (4), e0122622, 2015 | 79 | 2015 |
Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions AR Pedrosa, A Trindade, C Carvalho, J Graça, S Carvalho, MC Peleteiro, ... Oncotarget 6 (27), 24404, 2015 | 75 | 2015 |
Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle D Murta, M Batista, E Silva, A Trindade, D Henrique, A Duarte, ... PloS one 8 (8), e72767, 2013 | 74 | 2013 |
In Vivo Notch Signaling Blockade Induces Abnormal Spermatogenesis in the Mouse D Murta, M Batista, A Trindade, E Silva, D Henrique, A Duarte, ... PloS one 9 (11), e113365, 2014 | 52 | 2014 |
Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesis A Trindade, D Djokovic, J Gigante, M Badenes, AR Pedrosa, ... PloS one 7 (1), e29863, 2012 | 49 | 2012 |
Notch signaling dynamics in the adult healthy prostate and in prostatic tumor development AR Pedrosa, JL Graça, S Carvalho, MC Peleteiro, A Duarte, A Trindade The Prostate 76 (1), 80-96, 2016 | 38 | 2016 |
Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo A Trindade, D Djokovic, J Gigante, L Mendonça, A Duarte BMC cancer 17, 1-13, 2017 | 33 | 2017 |
Notch signaling in the epididymal epithelium regulates sperm motility and is transferred at a distance within epididymosomes D Murta, M Batista, E Silva, A Trindade, D Henrique, A Duarte, ... Andrology 4 (2), 314-327, 2016 | 31 | 2016 |
Differential expression of Notch component and effector genes during ovarian follicle and corpus luteum development during the oestrous cycle D Murta, M Batista, E Silva, A Trindade, L Mateus, A Duarte, ... Reproduction, Fertility and Development 27 (7), 1038-1048, 2015 | 30 | 2015 |
Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition and reduction of cancer stem cells and … L Mendonça, A Trindade, C Carvalho, J Correia, M Badenes, J Gigante, ... Clinical & experimental metastasis 36, 365-380, 2019 | 29 | 2019 |
Bone marrow-derived endothelial progenitors expressing Delta-like 4 (Dll4) regulate tumor angiogenesis C Real, L Remédio, F Caiado, C Igreja, C Borges, A Trindade, ... PLoS One 6 (4), e18323, 2011 | 25 | 2011 |
Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues R Liu, A Trindade, Z Sun, R Kumar, FA Weaver, V Krasnoperov, K Naga, ... Biochemical and Biophysical Research Communications 418 (1), 173-179, 2012 | 23 | 2012 |