Kristaps Jaudzems
Kristaps Jaudzems
Latvijas Organiskās sintēzes institūts
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Rapid proton-detected NMR assignment for proteins with fast magic angle spinning
E Barbet-Massin, AJ Pell, JS Retel, LB Andreas, K Jaudzems, WT Franks, ...
Journal of the American Chemical Society 136 (35), 12489-12497, 2014
2122014
Structure of fully protonated proteins by proton-detected magic-angle spinning NMR
LB Andreas, K Jaudzems, J Stanek, D Lalli, A Bertarello, T Le Marchand, ...
Proceedings of the National Academy of Sciences 113 (33), 9187-9192, 2016
1762016
Carbonic Anhydrase Generates CO2 and H+ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains
M Andersson, G Chen, M Otikovs, M Landreh, K Nordling, N Kronqvist, ...
PLoS biology 12 (8), e1001921, 2014
1272014
Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation
N Kronqvist, M Otikovs, V Chmyrov, G Chen, M Andersson, K Nordling, ...
Nature communications 5 (1), 1-11, 2014
1072014
High-resolution proton-detected NMR of proteins at very fast MAS
LB Andreas, T Le Marchand, K Jaudzems, G Pintacuda
Journal of magnetic resonance 253, 36-49, 2015
1022015
NMR spectroscopic assignment of backbone and side‐chain protons in fully protonated proteins: microcrystals, sedimented assemblies, and amyloid fibrils
J Stanek, LB Andreas, K Jaudzems, D Cala, D Lalli, A Bertarello, ...
Angewandte Chemie International Edition 55 (50), 15504-15509, 2016
932016
pH‐Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain
K Jaudzems, G Askarieh, M Landreh, K Nordling, M Hedhammar, ...
Journal of molecular biology 422 (4), 477-487, 2012
682012
Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism
K Jaudzems, J Kuka, A Gutsaits, K Zinovjevs, I Kalvinsh, E Liepinsh, ...
Journal of enzyme inhibition and medicinal chemistry 24 (6), 1269-1275, 2009
602009
Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity
R Aleksis, F Oleskovs, K Jaudzems, J Pahnke, H Biverstĺl
Biochimie 140, 176-192, 2017
482017
Out-and-back 13C–13C scalar transfers in protein resonance assignment by proton-detected solid-state NMR under ultra-fast MAS
E Barbet-Massin, AJ Pell, K Jaudzems, WT Franks, JS Retel, S Kotelovica, ...
Journal of biomolecular NMR 56 (4), 379-386, 2013
482013
Efficient protein production inspired by how spiders make silk
N Kronqvist, M Sarr, A Lindqvist, K Nordling, M Otikovs, L Venturi, ...
Nature communications 8 (1), 1-15, 2017
442017
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV
D Rasina, M Otikovs, J Leitans, R Recacha, OV Borysov, I Kanepe-Lapsa, ...
Journal of medicinal chemistry 59 (1), 374-387, 2016
432016
Discovery and structure–activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase
D Zhulenkovs, Z Rudevica, K Jaudzems, M Turks, A Leonchiks
Bioorganic & medicinal chemistry 22 (21), 5988-6003, 2014
432014
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit
K Jaudzems, K Tars, G Maurops, N Ivdra, M Otikovs, J Leitans, ...
ACS medicinal chemistry letters 5 (4), 373-377, 2014
402014
Dynamic Nuclear Polarization‐Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic‐Angle Spinning
K Jaudzems, A Bertarello, SR Chaudhari, A Pica, D Cala‐De Paepe, ...
Angewandte Chemie International Edition 57 (25), 7458-7462, 2018
352018
Structure of AP205 coat protein reveals circular permutation in ssRNA bacteriophages
M Shishovs, J Rumnieks, C Diebolder, K Jaudzems, LB Andreas, ...
Journal of molecular biology 428 (21), 4267-4279, 2016
352016
Is protein deuteration beneficial for proton detected solid-state NMR at and above 100 kHz magic-angle spinning?
D Cala-De Paepe, J Stanek, K Jaudzems, K Tars, LB Andreas, ...
Solid state nuclear magnetic resonance 87, 126-136, 2017
312017
DNP NMR of biomolecular assemblies
K Jaudzems, T Polenova, G Pintacuda, H Oschkinat, A Lesage
Journal of structural biology 206 (1), 90-98, 2019
302019
Diversified Structural Basis of a Conserved Molecular Mechanism for pH‐Dependent Dimerization in Spider Silk N‐Terminal Domains
M Otikovs, G Chen, K Nordling, M Landreh, Q Meng, H Jörnvall, ...
Chembiochem 16 (12), 1720-1724, 2015
292015
O-tert-Butyltyrosine, an NMR Tag for High-Molecular-Weight Systems and Measurements of Submicromolar Ligand Binding Affinities
WN Chen, KV Kuppan, MD Lee, K Jaudzems, T Huber, G Otting
Journal of the American Chemical Society 137 (13), 4581-4586, 2015
282015
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Artikelen 1–20