Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase DD Schlaepfer, SK Hanks, T Hunter, P Geer Nature 372 (6508), 786-791, 1994 | 2101 | 1994 |
PROTEIN-TYROSINE KINASES AND THEIR SIGNAL TRANSDUCTION PATHWAYS P Van der Geer, T Hunter Annu. Rev. Cell Biol 10, 251-337, 1994 | 1931 | 1994 |
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. WJ Boyle, P Van der Geer, T Hunter Methods in enzymology 201, 110-149, 1991 | 1699 | 1991 |
Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain C Trautwein, C Caelles, P van der Geer, T Hunter, M Karin, M Chojkier Nature 364 (6437), 544-547, 1993 | 418 | 1993 |
The PTB domain: a new protein module implicated in signal transduction P Van der Geer, T Pawson Trends in biochemical sciences 20 (7), 277-280, 1995 | 380 | 1995 |
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity SE Wiley, AN Murphy, SA Ross, P van der Geer, JE Dixon Proceedings of the National Academy of Sciences 104 (13), 5318-5323, 2007 | 328 | 2007 |
The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein–protein interactions P van der Geer, S Wiley, GD Gish, T Pawson Current Biology 6 (11), 1435-1444, 1996 | 283 | 1996 |
Tyr721 regulates specific binding of the CSF‐1 receptor kinase insert to PI 3′‐kinase SH2 domains: a model for SH2‐mediated receptor‐target interactions. M Reedijk, X Liu, P van der Geer, K Letwin, MD Waterfield, T Hunter, ... The EMBO journal 11 (4), 1365-1372, 1992 | 269 | 1992 |
RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization H Tourrière, I Gallouzi, K Chebli, JP Capony, J Mouaikel, P van der Geer, ... Molecular and cellular biology, 2001 | 245 | 2001 |
A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides P van der Geer, S Wiley, VKM Lai, JP Olivier, GD Gish, R Stephens, ... Current Biology 5 (4), 404-412, 1995 | 212 | 1995 |
Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBPβ is required for hepatocyte proliferation induced by TGFα M Buck, V Poli, P van der Geer, M Chojkier, T Hunter Molecular cell 4 (6), 1087-1092, 1999 | 211 | 1999 |
Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elements. C Trautwein, P Van der Geer, M Karin, T Hunter, M Chojkier The Journal of clinical investigation 93 (6), 2554-2561, 1994 | 206 | 1994 |
Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1 X Piao, R Paulson, P Van Der Geer, T Pawson, A Bernstein Proceedings of the National Academy of Sciences 93 (25), 14665-14669, 1996 | 201 | 1996 |
A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C. E Freed, J Gailit, P van der Geer, E Ruoslahti, T Hunter The EMBO Journal 8 (10), 2955-2965, 1989 | 197 | 1989 |
The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster SE Wiley, ML Paddock, EC Abresch, L Gross, P van der Geer, ... Journal of Biological Chemistry 282 (33), 23745-23749, 2007 | 193 | 2007 |
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium JR MacFadyen, O Haworth, D Roberston, D Hardie, MT Webster, ... FEBS letters 579 (12), 2569-2575, 2005 | 192 | 2005 |
Mutation of Tyr697, a GRB2‐binding site, and Tyr721, a PI 3‐kinase binding site, abrogates signal transduction by the murine CSF‐1 receptor expressed in Rat‐2 fibroblasts. P van der Geer, T Hunter The EMBO journal 12 (13), 5161-5172, 1993 | 180 | 1993 |
Role of p120 Ras-GAP in directed cell movement SV Kulkarni, G Gish, P Van Der Geer, M Henkemeyer, T Pawson The Journal of cell biology 149 (2), 457-470, 2000 | 173 | 2000 |
Phosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin‐layer cellulose plates P van der Geer, T Hunter Electrophoresis 15 (1), 544-554, 1994 | 158 | 1994 |
Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC-transformed cells H Barnes, B Larsen, M Tyers, P van der Geer Journal of Biological Chemistry 276 (22), 19119-19125, 2001 | 140 | 2001 |