Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons K Castillo, M Nassif, V Valenzuela, F Rojas, S Matus, G Mercado, ... Autophagy 9 (9), 1308-1320, 2013 | 350 | 2013 |
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 P Valdés, G Mercado, RL Vidal, C Molina, G Parsons, A Martinez, ... Proceedings of the National Academy of Sciences 111 (18), 6804-6809, 2014 | 219 | 2014 |
An ERcentric view of Parkinson's disease G Mercado, P Valdés, C Hetz Trends in molecular medicine 19 (3), 165-175, 2013 | 218 | 2013 |
Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease G Mercado, V Castillo, P Soto, N López, JM Axten, SP Sardi, ... Neurobiology of disease 112, 136-148, 2018 | 145 | 2018 |
Antibacterial and antitumorigenic properties of microcin E492, a pore-forming bacteriocin R Lagos, M Tello, G Mercado, V García, O Monasterio Current pharmaceutical biotechnology 10 (1), 74-85, 2009 | 130 | 2009 |
ER stress and Parkinson's disease: pathological inputs that converge into the secretory pathway G Mercado, V Castillo, P Soto, A Sidhu Brain research 1648, 626-632, 2016 | 124 | 2016 |
Can infections trigger alpha-synucleinopathies? CT Tulisiak, G Mercado, W Peelaerts, L Brundin, P Brundin Progress in molecular biology and translational science 168, 299-322, 2019 | 74 | 2019 |
Functional role of the disulfide isomerase ERp57 in axonal regeneration V Castillo, M Oñate, U Woehlbier, P Rozas, C Andreu, D Medinas, ... PLoS One 10 (9), e0136620, 2015 | 52 | 2015 |
Microcin E492 amyloid formation is retarded by posttranslational modification A Marcoleta, M Marín, G Mercado, JM Valpuesta, O Monasterio, R Lagos Journal of bacteriology 195 (17), 3995-4004, 2013 | 36 | 2013 |
Deficits in olfactory sensitivity in a mouse model of Parkinson’s disease revealed by plethysmography of odor-evoked sniffing ME Johnson, L Bergkvist, G Mercado, L Stetzik, L Meyerdirk, E Wolfrum, ... Scientific reports 10 (1), 9242, 2020 | 33 | 2020 |
Structural characterization of microcin E492 amyloid formation: Identification of the precursors R Arranz, G Mercado, J Martín-Benito, R Giraldo, O Monasterio, R Lagos, ... Journal of Structural Biology 178 (1), 54-60, 2012 | 33 | 2012 |
ER proteostasis disturbances in Parkinson's disease: novel insights G Mercado, V Castillo, R Vidal, C Hetz Frontiers in aging neuroscience 7, 39, 2015 | 29 | 2015 |
The production in vivo of microcin E492 with antibacterial activity depends on salmochelin and EntF G Mercado, M Tello, M Marín, O Monasterio, R Lagos Journal of bacteriology 190 (15), 5464-5471, 2008 | 25 | 2008 |
Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational efforts G Mercado, C Hetz Brain 140 (6), 1544-1547, 2017 | 22 | 2017 |
Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality D Sargent, LA Cunningham, DJ Dues, Y Ma, JJ Kordich, G Mercado, ... Brain Communications 3 (3), fcab208, 2021 | 15 | 2021 |
An extended release GLP-1 analogue increases α-synuclein accumulation in a mouse model of prodromal Parkinson's disease L Bergkvist, ME Johnson, G Mercado, JA Steiner, L Meyerdirk, E Schulz, ... Experimental Neurology 341, 113693, 2021 | 13 | 2021 |
Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis BA Killinger, G Mercado, S Choi, T Tittle, Y Chu, P Brundin, JH Kordower npj Parkinson's Disease 9 (1), 43, 2023 | 12 | 2023 |
A new model to study cell-to-cell transfer of αSynuclein in vivo G Mercado, N López, A Martínez, SP Sardi, C Hetz Biochemical and biophysical research communications 503 (3), 1385-1393, 2018 | 8 | 2018 |
Gene therapy in Parkinson's disease: targeting the endplasmic reticulum proteostasis network V Castillo, G Mercado, C Hetz Neural regeneration research 10 (7), 1053, 2015 | 8 | 2015 |
Urinary tract infections trigger synucleinopathy via the innate immune response W Peelaerts, G Mercado, S George, M Villumsen, A Kasen, M Aguileta, ... Acta neuropathologica 145 (5), 541-559, 2023 | 6 | 2023 |