| Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells MA Israel, SH Yuan, C Bardy, SM Reyna, Y Mu, C Herrera, MP Hefferan, ... Nature 482 (7384), 216-220, 2012 | 1408 | 2012 |
| Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells SH Yuan, J Martin, J Elia, J Flippin, RI Paramban, MP Hefferan, JG Vidal, ... PloS one 6 (3), e17540, 2011 | 442 | 2011 |
| The Rheb–mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord S Codeluppi, CI Svensson, MP Hefferan, F Valencia, MD Silldorff, ... Journal of Neuroscience 29 (4), 1093-1104, 2009 | 193 | 2009 |
| Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation MP Hefferan, J Galik, O Kakinohana, G Sekerkova, C Santucci, S Marsala, ... Public Library of Science 7 (8), e42614, 2012 | 127 | 2012 |
| Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells D Cizkova, O Kakinohana, K Kucharova, S Marsala, K Johe, T Hazel, ... Neuroscience 147 (2), 546-560, 2007 | 119 | 2007 |
| Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis CW Loomis, H Khandwala, G Osmond, MP Hefferan Journal of Pharmacology and Experimental Therapeutics 296 (3), 756-761, 2001 | 96 | 2001 |
| REVIEW ARTILCE: Cell therapy and stem cells in animal models of motor neuron disorders E Hedlund, MP Hefferan, M Marsala, O Isacson European journal of neuroscience 26 (7), 1721-1737, 2007 | 88 | 2007 |
| The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers N Emre, JG Vidal, J Elia, ED O'Connor, RI Paramban, MP Hefferan, ... PloS one 5 (8), e12148, 2010 | 83 | 2010 |
| Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study O Kakinohana, MP Hefferan, S Nakamura, M Kakinohana, J Galik, ... Neuroscience 141 (3), 1569-1583, 2006 | 78 | 2006 |
| Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery JS Lunn, MP Hefferan, M Marsala, EL Feldman Growth Factors 27 (3), 133-140, 2009 | 76 | 2009 |
| Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs D Usvald, P Vodicka, J Hlucilova, R Prochazka, J Motlik, K Kuchorova, ... Cell transplantation 19 (9), 1103-1122, 2010 | 63 | 2010 |
| Pig models of neurodegenerative disorders: Utilization in cell replacement‐based preclinical safety and efficacy studies D Dolezalova, M Hruska‐Plochan, CR Bjarkam, JCH Sørensen, ... Journal of Comparative Neurology 522 (12), 2784-2801, 2014 | 57 | 2014 |
| Inhibition of spinal prostaglandin synthesis early after L5/L6 nerve ligation prevents the development of prostaglandin-dependent and prostaglandin-independent allodynia in the rat MP Hefferan, DD O'Rielly, CW Loomis The Journal of the American Society of Anesthesiologists 99 (5), 1180-1188, 2003 | 54 | 2003 |
| Spinal nerve injury activates prostaglandin synthesis in the spinal cord that contributes to early maintenance of tactile allodynia MP Hefferan, P Carter, M Haley, CW Loomis Pain 101 (1-2), 139-147, 2003 | 52 | 2003 |
| Survival of syngeneic and allogeneic iPSC–derived neural precursors after spinal grafting in minipigs J Strnadel, C Carromeu, C Bardy, M Navarro, O Platoshyn, AN Glud, ... Science translational medicine 10 (440), eaam6651, 2018 | 49 | 2018 |
| Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity MP Hefferan, K Kucharova, K Kinjo, O Kakinohana, G Sekerkova, ... Journal of Neuroscience 27 (42), 11179-11191, 2007 | 47 | 2007 |
| In vivo gene knockdown in rat dorsal root ganglia mediated by self-complementary adeno-associated virus serotype 5 following intrathecal delivery Q Xu, B Chou, B Fitzsimmons, A Miyanohara, V Shubayev, C Santucci, ... PloS one 7 (3), e32581, 2012 | 43 | 2012 |
| Spinal p38 mitogen‐activated protein kinase mediates allodynia induced by first‐degree burn in the rat L Sorkin, CI Svensson, TL Jones‐Cordero, MP Hefferan, WM Campana Journal of neuroscience research 87 (4), 948-955, 2009 | 42 | 2009 |
| Topical bicuculline to the rat spinal cord induces highly localized allodynia that is mediated by spinal prostaglandins Z Zhang, MP Hefferan, CW Loomis PAIN® 92 (3), 351-361, 2001 | 42 | 2001 |
| Optimization of immunosuppressive therapy for spinal grafting of human spinal stem cells in a rat model of ALS MP Hefferan, K Johe, T Hazel, EL Feldman, JS Lunn, M Marsala Cell transplantation 20 (8), 1153-1161, 2011 | 38 | 2011 |
