Thomas Dorlo
Thomas Dorlo
Pharmacometrician, Antoni van Leeuwenhoek Hospital / Netherlands Cancer Institute
Verified email at
TitleCited byYear
Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
TPC Dorlo, M Balasegaram, JH Beijnen, PJ de Vries
Journal of Antimicrobial Chemotherapy 67 (11), 2576-2597, 2012
Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance
S Rijal, B Ostyn, S Uranw, K Rai, NR Bhattarai, TPC Dorlo, JH Beijnen, ...
Clinical Infectious Diseases 56 (11), 1530-1538, 2013
Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients
TPC Dorlo, PPAM van Thiel, ADR Huitema, RJ Keizer, HJC de Vries, ...
Antimicrobial agents and chemotherapy 52 (8), 2855-2860, 2008
Failure of miltefosine in visceral leishmaniasis is associated with low drug exposure
TPC Dorlo, S Rijal, B Ostyn, PJ de Vries, R Singh, N Bhattarai, S Uranw, ...
The Journal of infectious diseases 210 (1), 146-153, 2014
Optimal dosing of miltefosine in children and adults with visceral leishmaniasis
TPC Dorlo, ADR Huitema, JH Beijnen, PJ de Vries
Antimicrobial agents and chemotherapy 56 (7), 3864-3872, 2012
LeishMan recommendations for treatment of cutaneous and mucosal leishmaniasis in travelers, 2014
J Blum, P Buffet, L Visser, G Harms, MS Bailey, E Caumes, J Clerinx, ...
Journal of travel medicine 21 (2), 116-129, 2014
Safety and efficacy of single dose versus multiple doses of AmBisome® for treatment of visceral leishmaniasis in eastern Africa: a randomised trial
EAG Khalil, T Weldegebreal, BM Younis, R Omollo, AM Musa, W Hailu, ...
PLoS neglected tropical diseases 8 (1), e2613, 2014
Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia
B Ostyn, E Hasker, TPC Dorlo, S Rijal, S Sundar, JC Dujardin, M Boelaert
PLoS One 9 (6), e100220, 2014
Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography–tandem mass spectrometry
TPC Dorlo, MJX Hillebrand, H Rosing, TA Eggelte, PJ de Vries, ...
Journal of Chromatography B 865 (1-2), 55-62, 2008
Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East …
R Omollo, N Alexander, T Edwards, EAG Khalil, BM Younis, AA Abuzaid, ...
Trials 12 (1), 166, 2011
Efficacy and safety of AmBisome in combination with sodium stibogluconate or miltefosine and miltefosine monotherapy for African visceral leishmaniasis: phase II randomized trial
M Wasunna, S Njenga, M Balasegaram, N Alexander, R Omollo, ...
PLoS neglected tropical diseases 10 (9), e0004880, 2016
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults
P Byakika-Kibwika, M Lamorde, V Okaba-Kayom, H Mayanja-Kizza, ...
Journal of antimicrobial chemotherapy 67 (5), 1217-1223, 2012
A poor-quality generic drug for the treatment of visceral leishmaniasis: a case report and appeal
TPC Dorlo, TA Eggelte, GJ Schoone, PJ de Vries, JH Beijnen
PLoS neglected tropical diseases 6 (5), e1544, 2012
Systematic review of biomarkers to monitor therapeutic response in leishmaniasis
AE Kip, M Balasegaram, JH Beijnen, JHM Schellens, PJ de Vries, ...
Antimicrobial agents and chemotherapy 59 (1), 1-14, 2015
Severe encephalopathy and polyneuropathy induced by dichloroacetate
D Brandsma, TPC Dorlo, JH Haanen, JH Beijnen, W Boogerd
Journal of neurology 257 (12), 2099-2100, 2010
Pentamidine dosage: a base/salt confusion
TPC Dorlo, PA Kager
PLoS neglected tropical diseases 2 (5), e225, 2008
Characterization and identification of suspected counterfeit miltefosine capsules
TPC Dorlo, TA Eggelte, PJ de Vries, JH Beijnen
Analyst 137 (5), 1265-1274, 2012
Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine
TPC Dorlo, M Balasegaram, MA Lima, PJ de Vries, JH Beijnen, ...
Journal of antimicrobial chemotherapy 67 (8), 1996-2004, 2012
Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples
AE Kip, KC Kiers, H Rosing, JHM Schellens, JH Beijnen, TPC Dorlo
Journal of pharmaceutical and biomedical analysis 135, 160-166, 2017
Dose reduction of caspofungin in intensive care unit patients with Child Pugh B will result in suboptimal exposure
LC Martial, RJM Brüggemann, JA Schouten, HJ van Leeuwen, ...
Clinical pharmacokinetics 55 (6), 723-733, 2016
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