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Thomas Dorlo
Thomas Dorlo
Associate Professor in Pharmacometrics, Uppsala University
Verified email at farmaci.uu.se - Homepage
Title
Cited by
Cited by
Year
Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
TPC Dorlo, M Balasegaram, JH Beijnen, PJ de Vries
Journal of Antimicrobial Chemotherapy 67 (11), 2576-2597, 2012
8212012
Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance
S Rijal, B Ostyn, S Uranw, K Rai, NR Bhattarai, TPC Dorlo, JH Beijnen, ...
Clinical Infectious Diseases 56 (11), 1530-1538, 2013
3532013
Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients
TPC Dorlo, PPAM van Thiel, ADR Huitema, RJ Keizer, HJC de Vries, ...
Antimicrobial agents and chemotherapy 52 (8), 2855-2860, 2008
1962008
Failure of miltefosine in visceral leishmaniasis is associated with low drug exposure
TPC Dorlo, S Rijal, B Ostyn, PJ de Vries, R Singh, N Bhattarai, S Uranw, ...
The Journal of infectious diseases 210 (1), 146-153, 2014
1532014
LeishMan recommendations for treatment of cutaneous and mucosal leishmaniasis in travelers, 2014
J Blum, P Buffet, L Visser, G Harms, MS Bailey, E Caumes, J Clerinx, ...
Journal of travel medicine 21 (2), 116-129, 2014
1322014
Optimal dosing of miltefosine in children and adults with visceral leishmaniasis
TPC Dorlo, ADR Huitema, JH Beijnen, PJ de Vries
Antimicrobial agents and chemotherapy 56 (7), 3864-3872, 2012
1232012
Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia
B Ostyn, E Hasker, TPC Dorlo, S Rijal, S Sundar, JC Dujardin, M Boelaert
PloS one 9 (6), e100220, 2014
882014
Efficacy and safety of AmBisome in combination with sodium stibogluconate or miltefosine and miltefosine monotherapy for African visceral leishmaniasis: phase II randomized trial
M Wasunna, S Njenga, M Balasegaram, N Alexander, R Omollo, ...
PLoS neglected tropical diseases 10 (9), e0004880, 2016
872016
Safety and efficacy of single dose versus multiple doses of AmBisomeŽ for treatment of visceral leishmaniasis in eastern Africa: a randomised trial
EAG Khalil, T Weldegebreal, BM Younis, R Omollo, AM Musa, W Hailu, ...
PLoS neglected tropical diseases 8 (1), e2613, 2014
852014
Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples
AE Kip, KC Kiers, H Rosing, JHM Schellens, JH Beijnen, TPC Dorlo
Journal of pharmaceutical and biomedical analysis 135, 160-166, 2017
812017
Clinical pharmacokinetics of systemically administered antileishmanial drugs
AE Kip, JHM Schellens, JH Beijnen, TPC Dorlo
Clinical pharmacokinetics 57 (2), 151-176, 2018
742018
Systematic review of biomarkers to monitor therapeutic response in leishmaniasis
AE Kip, M Balasegaram, JH Beijnen, JHM Schellens, PJ de Vries, ...
Antimicrobial agents and chemotherapy 59 (1), 1-14, 2015
692015
Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East …
R Omollo, N Alexander, T Edwards, EAG Khalil, BM Younis, AA Abuzaid, ...
Trials 12, 1-10, 2011
682011
Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography–tandem mass spectrometry
TPC Dorlo, MJX Hillebrand, H Rosing, TA Eggelte, PJ de Vries, ...
Journal of Chromatography B 865 (1-2), 55-62, 2008
662008
Pharmacokinetics of miltefosine in children and adults with cutaneous leishmaniasis
MM Castro, MA Gomez, AE Kip, A Cossio, E Ortiz, A Navas, TPC Dorlo, ...
Antimicrobial agents and chemotherapy 61 (3), 10.1128/aac. 02198-16, 2017
582017
Characterization and identification of suspected counterfeit miltefosine capsules
TPC Dorlo, TA Eggelte, PJ de Vries, JH Beijnen
Analyst 137 (5), 1265-1274, 2012
582012
Population pharmacokinetics of fludarabine in children and adults during conditioning prior to allogeneic hematopoietic cell transplantation
JB Langenhorst, TPC Dorlo, EM van Maarseveen, S Nierkens, J Kuball, ...
Clinical pharmacokinetics 58, 627-637, 2019
552019
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults
P Byakika-Kibwika, M Lamorde, V Okaba-Kayom, H Mayanja-Kizza, ...
Journal of antimicrobial chemotherapy 67 (5), 1217-1223, 2012
552012
Severe encephalopathy and polyneuropathy induced by dichloroacetate
D Brandsma, TPC Dorlo, JH Haanen, JH Beijnen, W Boogerd
Journal of neurology 257, 2099-2100, 2010
532010
Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes
JB Langenhorst, C Van Kesteren, EM Van Maarseveen, TPC Dorlo, ...
Blood advances 3 (14), 2179-2187, 2019
512019
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