| A dictionary to identify small molecules and drugs in free text KM Hettne, RH Stierum, MJ Schuemie, PJM Hendriksen, ... Bioinformatics 25 (22), 2983-2991, 2009 | 194 | 2009 |
| FAIR principles: interpretations and implementation considerations A Jacobsen, R de Miranda Azevedo, N Juty, D Batista, S Coles, R Cornet, ... Data Intelligence 2 (1-2), 10-29, 2020 | 182 | 2020 |
| Using a suite of ontologies for preserving workflow-centric research objects K Belhajjame, J Zhao, D Garijo, M Gamble, K Hettne, R Palma, E Mina, ... Journal of Web Semantics 32, 16-42, 2015 | 163 | 2015 |
| Why workflows break—Understanding and combating decay in Taverna workflows J Zhao, JM Gomez-Perez, K Belhajjame, G Klyne, E Garcia-Cuesta, ... 2012 IEEE 8th International Conference on e-Science, 1-9, 2012 | 139 | 2012 |
| Automatic mining of the literature to generate new hypotheses for the possible link between periodontitis and atherosclerosis: lipopolysaccharide as a case study KM Hettne, M Weeber, ML Laine, H Cate, S Boyer, JA Kors, BG Loos Journal of clinical periodontology 34 (12), 1016-1024, 2007 | 59 | 2007 |
| Towards the preservation of scientific workflows D De Roure, K Belhajjame, P Missier, J Manuel, R Palma, JE Ruiz, ... Proc. 8th Intl. Conference on Preservation of Digital Objects, 2011 | 57 | 2011 |
| Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining KM Hettne, AJ Williams, EM van Mulligen, J Kleinjans, V Tkachenko, ... Journal of cheminformatics 2 (1), 1-7, 2010 | 56 | 2010 |
| Chemical and biological profiling of an annotated compound library directed to the nuclear receptor family M Cases, R García-Serna, K Hettne, M Weeber, JV Lei, S Boyer, ... Current topics in medicinal chemistry 5 (8), 763-772, 2005 | 55 | 2005 |
| Selective glucocorticoid receptor modulation prevents and reverses nonalcoholic fatty liver disease in male mice LL Koorneef, JK van den Heuvel, J Kroon, MR Boon, PAC ’t Hoen, ... Endocrinology 159 (12), 3925-3936, 2018 | 49 | 2018 |
| Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington’s disease peripheral blood samples A Mastrokolias, R Pool, E Mina, KM Hettne, E van Duijn, RC van der Mast, ... Metabolomics 12, 1-15, 2016 | 47 | 2016 |
| Rewriting and suppressing UMLS terms for improved biomedical term identification KM Hettne, EM van Mulligen, MJ Schuemie, BJA Schijvenaars, JA Kors Journal of biomedical semantics 1 (1), 1-14, 2010 | 47 | 2010 |
| Tracking disease progression non‐invasively in Duchenne and Becker muscular dystrophies P Spitali, K Hettne, R Tsonaka, M Charrout, J van den Bergen, Z Koeks, ... Journal of Cachexia, Sarcopenia and Muscle 9 (4), 715-726, 2018 | 46 | 2018 |
| Best practices for workflow design: how to prevent workflow decay K Hettne, K Wolstencroft, K Belhajjame, C Goble, E Mina, H Dharuri, ... Semantic Web Applications and Tools for the Life Sciences (SWAT4LS 2012), 2012 | 43 | 2012 |
| Early career researchers want Open Science A Farnham, C Kurz, MA Öztürk, M Solbiati, O Myllyntaus, J Meekes, ... Genome biology 18 (1), 1-4, 2017 | 41 | 2017 |
| Recognition of chemical entities: combining dictionary-based and grammar-based approaches SA Akhondi, KM Hettne, E van der Horst, EM van Mulligen, JA Kors J Cheminform 7 (Suppl 1), S10, 2015 | 41 | 2015 |
| Applied information retrieval and multidisciplinary research: new mechanistic hypotheses in complex regional pain syndrome KM Hettne, M De Mos, AGJ De Bruijn, M Weeber, S Boyer, ... Journal of biomedical discovery and collaboration 2, 1-16, 2007 | 40 | 2007 |
| Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model LJA Toonen, M Overzier, MM Evers, LG Leon, SAJ van der Zeeuw, H Mei, ... Molecular Neurodegeneration 13, 1-18, 2018 | 37 | 2018 |
| The implicitome: a resource for rationalizing gene-disease associations KM Hettne, M Thompson, HH van Haagen, E Van Der Horst, ... PLoS one 11 (2), e0149621, 2016 | 36 | 2016 |
| Structuring research methods and data with the research object model: genomics workflows as a case study KM Hettne, H Dharuri, J Zhao, K Wolstencroft, K Belhajjame, ... Journal of biomedical semantics 5, 1-16, 2014 | 34 | 2014 |
| Literature-aided interpretation of gene expression data with the weighted global test R Jelier, JJ Goeman, KM Hettne, MJ Schuemie, JT den Dunnen, ... Briefings in bioinformatics 12 (5), 518-529, 2011 | 33 | 2011 |
Marco RoosLeiden University Medical Centre, Human Genetics Department, BioSemantics groupVerified email at lumc.nl
