Edze Westra - Google Scholar Citations

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Stan J.J. BrounsAssociate Professor Molecular Microbiology, Delft University of TechnologyVerified email at tudelft.nl
Angus BucklingUniversity of ExeterVerified email at exeter.ac.uk
Blake WiedenheftAssistant Professor Microbiology and Immunology, Montana State UniversityVerified email at montana.edu
Raymond StaalsAssistant Professor, Wageningen UniversityVerified email at wur.nl
Mark J DickmanProfessor of Bioanalytical Science and Engineering, Dept of Chemical and Biological EngineeringVerified email at sheffield.ac.uk
Sylvain GANDONDirecteur de recherche au CNRS - CEFE, MontpellierVerified email at cefe.cnrs.fr
Daan C. SwartsAssistant Professor/Personal Investigator | Wageningen University & ResearchVerified email at wur.nl
Ümit PulSenior Principal Scientist, EW Nutrition GmbHVerified email at online.de
Tim KünneWageningen University and ResearchVerified email at wur.nl
Eugene KooninSenior Investigator, NCBI, NIHVerified email at ncbi.nlm.nih.gov
Kira MakarovaNCBI, NIHVerified email at ncbi.nlm.nih.gov
Peter FineranProfessor, University of Otago, New ZealandVerified email at otago.ac.nz
Albert J. R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht UniversityVerified email at uu.nl
Remus T. Dame, PhDLeiden University, Leiden Institute of Chemistry, Centre for Microbial Cell BiologyVerified email at chem.leidenuniv.nl
Mike BootsUC BerkeleyVerified email at berkeley.edu
Alan R. DavidsonUniversity of TorontoVerified email at utoronto.ca
Willem M de VosProfessor @ Microbiology Wageningen Netherlands @Helsinki FinlandVerified email at wur.nl
Renko de VriesWageningen UniversityVerified email at wur.nl
Sinan Al-ATTARCentre National de la Recherche Scientifique, Marseille, FranceVerified email at imm.cnrs.fr
Ben AshbyResearch Fellow (Assistant Prof.), Mathematical Sciences & Milner Centre for Evolution, Uni BathVerified email at bath.ac.uk

Edze Westra

Professor of Microbiology, University of Exeter, Biosciences, ESI

Verified email at exeter.ac.uk

Mechanism and Evolution of Bacterial Immune Mechanisms


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Small CRISPR RNAs guide antiviral defense in prokaryotes SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ... Science 321 (5891), 960-964, 2008	1996	2008
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011	683	2011
Unravelling the structural and mechanistic basis of CRISPR–Cas systems J Van Der Oost, ER Westra, RN Jackson, B Wiedenheft Nature Reviews Microbiology 12 (7), 479-492, 2014	512	2014
CRISPR-based adaptive and heritable immunity in prokaryotes J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns Trends in biochemical sciences 34 (8), 401-407, 2009	495	2009
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012	491	2012
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529, 2011	491	2011
The CRISPRs, They Are A-Changin': How Prokaryotes Generate Adaptive Immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual Reviews of Genetics 46 (1), 311, 2012	288	2012
DNA-guided DNA interference by a prokaryotic Argonaute DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ... Nature 507 (7491), 258-261, 2014	228	2014
CRISPR–Cas systems: beyond adaptive immunity ER Westra, A Buckling, PC Fineran Nature reviews Microbiology 12 (5), 317-326, 2014	227	2014
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO ER Westra, Ü Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ... Molecular microbiology 77 (6), 1380-1393, 2010	213	2010
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014	196	2014
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS genetics 9 (9), 2013	167	2013
Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes S Al-Attar, ER Westra, J Van Der Oost, SJJ Brouns Biological chemistry 392 (4), 277-289, 2011	154	2011
Parasite exposure drives selective evolution of constitutive versus inducible defense ER Westra, S van Houte, S Oyesiku-Blakemore, B Makin, JM Broniewski, ... Current biology 25 (8), 1043-1049, 2015	140	2015
The diversity-generating benefits of a prokaryotic adaptive immune system S van Houte, AKE Ekroth, JM Broniewski, H Chabas, B Ashby, ... Nature 532 (7599), 385-388, 2016	128	2016
Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system NM Høyland-Kroghsbo, J Paczkowski, S Mukherjee, J Broniewski, ... Proceedings of the National Academy of Sciences 114 (1), 131-135, 2017	96	2017
Evolutionary ecology of prokaryotic immune mechanisms S van Houte, A Buckling, ER Westra Microbiol. Mol. Biol. Rev. 80 (3), 745-763, 2016	91	2016
Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex TR Blosser, L Loeff, ER Westra, M Vlot, T Künne, M Sobota, C Dekker, ... Molecular cell 58 (1), 60-70, 2015	88	2015
Prophages mediate defense against phage infection through diverse mechanisms J Bondy-Denomy, J Qian, ER Westra, A Buckling, DS Guttman, ... The ISME journal 10 (12), 2854-2866, 2016	85	2016
Native tandem and ion mobility mass spectrometry highlight structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated … E van Duijn, IM Barbu, A Barendregt, MM Jore, B Wiedenheft, M Lundgren, ... Molecular & Cellular Proteomics 11 (11), 1430-1441, 2012	74	2012

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