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Zheng Hu
Zheng Hu
Principal Investigator, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences (CAS)
Geverifieerd e-mailadres voor siat.ac.cn - Homepage
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Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution
S Ling#, Z Hu#, Z Yang#, F Yang#, Y Li, P Lin, K Chen, L Dong, L Cao, ...
Proceedings of the National Academy of Sciences 112 (47), E6496-E6505, 2015
3862015
Quantitative evidence for early metastatic seeding in colorectal cancer
Z Hu, J Ding, Z Ma, R Sun, JA Seoane, J Scott Shaffer, CJ Suarez, ...
Nature genetics 51 (7), 1113-1122, 2019
3562019
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases
Z Hu, Z Li, Z Ma, C Curtis
Nature Genetics 52, 701–708, 2020
2432020
Between-region genetic divergence reflects the mode and tempo of tumor evolution
R Sun#, Z Hu#, A Sottoriva, TA Graham, A Harpak, Z Ma, JM Fischer, ...
Nature Genetics 49 (7), 1015-1024, 2017
1692017
A population genetics perspective on the determinants of intra-tumor heterogeneity
Z Hu, R Sun, C Curtis
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1867 (2), 109–126, 2017
602017
Intron 3 16 bp duplication polymorphism of TP53 contributes to cancer susceptibility
Z Hu, X Li, X Qu, Y He, BZ Ring, L Su
Carcinogenesis 31 (4), 643-647, 2010
562010
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
JL Caswell-Jin, K McNamara, JG Reiter, R Sun, Z Hu, Z Ma, J Ding, ...
Nature communications 10 (1), 657, 2019
542019
Looking backward in time to define the chronology of metastasis
Z Hu, C Curtis
Nature Communications 11 (1), 1-4, 2020
492020
Big Bang tumor growth and clonal evolution
R Sun, Z Hu, C Curtis
Cold Spring Harbor Perspectives in Medicine, doi: 10.1101/cshperspect.a028381, 2017
472017
Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers
X Li#, Z Hu#, X Qu, J Zhu, L Li, BZ Ring, L Su
PLoS ONE 6 ((3):e14749), 2011
462011
Is the evolution in tumors Darwinian or non-Darwinian?
HY Wang, Y Chen, D Tong, S Ling, Z Hu, Y Tao, X Lu, CI Wu
National Science Review, https://doi.org/10.1093/nsr/nwx076, 2018
302018
Genetic load and potential mutational meltdown in cancer cell populations
Y Zhang, Y Li, T Li, X Shen, T Zhu, Y Tao, X Li, D Wang, Q Ma, Z Hu, J Liu, ...
Molecular biology and evolution 36 (3), 541-552, 2019
222019
Age-dependent transition from cell-level to population-level control in murine intestinal homeostasis revealed by coalescence analysis
Z Hu, YX Fu, AJ Greenberg, CI Wu, W Zhai
PLoS Genetics 9 ((2):e1003326), 2013
172013
Patient‐Derived Upper Tract Urothelial Carcinoma Organoids as a Platform for Drug Screening
Z Li, H Xu, Y Gong, W Chen, Y Zhan, L Yu, Y Sun, A Li, S He, B Guan, ...
Advanced Science 9 (4), 2103999, 2022
132022
Further genetic diversification in multiple tumors and an evolutionary perspective on therapeutics
Y Tao#, Z Hu#, S Ling#, SH Yeh, W Zhai, K Chen, C Li, Y Wang, K Wang, ...
bioRxiv, 2015
112015
A genetic bottleneck of mitochondrial DNA during human lymphocyte development
Z Tang#, Z Lu#, B Chen, W Zhang, H Chang*, Z Hu*, J Xu*
Molecular Biology and Evolution, 2022
92022
Delineating the longitudinal tumor evolution using organoid models
Z Lu, B Nie, W Zhai, Z Hu
Journal of Genetics and Genomics 48 (7), 560-570, 2021
92021
PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes
K Wang, L Hou, X Wang, X Zhai, Z Lu, Z Zi, W Zhai, X He, C Curtis, ...
Nature Biotechnology, 1-12, 2023
82023
Inferring tumor phylogenies from multi-region sequencing
Z Hu, C Curtis
Cell Systems 3 (1), 12-14, 2016
52016
Cell division history encodes directional information of fate transitions
K Wang, L Hou, Z Lu, X Wang, Z Zi, W Zhai, X He, C Curtis, D Zhou, Z Hu
bioRxiv, 2022.10. 06.511094, 2022
42022
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Artikelen 1–20