|Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells|
JM Polo, S Liu, ME Figueroa, W Kulalert, S Eminli, KY Tan, E Apostolou, ...
Nature biotechnology 28 (8), 848-855, 2010
|Immortalization eliminates a roadblock during cellular reprogramming into iPS cells|
J Utikal, JM Polo, M Stadtfeld, N Maherali, W Kulalert, RM Walsh, A Khalil, ...
Nature 460 (7259), 1145-1148, 2009
|A molecular roadmap of reprogramming somatic cells into iPS cells|
JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ...
Cell 151 (7), 1617-1632, 2012
|Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice|
K Arnold, A Sarkar, MA Yram, JM Polo, R Bronson, S Sengupta, ...
Cell stem cell 9 (4), 317-329, 2011
|Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells|
Y Ohi, H Qin, C Hong, L Blouin, JM Polo, T Guo, Z Qi, SL Downey, ...
Nature cell biology 13 (5), 541-549, 2011
|Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes|
E Mariņo, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ...
Nature immunology 18 (5), 552-562, 2017
|Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells|
JM Polo, T Dell'Oso, SM Ranuncolo, L Cerchietti, D Beck, GF Da Silva, ...
Nature medicine 10 (12), 1329-1335, 2004
|A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo|
LC Cerchietti, AF Ghetu, X Zhu, GF Da Silva, S Zhong, M Matthews, ...
Cancer cell 17 (4), 400-411, 2010
|Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR|
SM Ranuncolo, JM Polo, J Dierov, M Singer, T Kuo, J Greally, R Green, ...
Nature immunology 8 (7), 705-714, 2007
|A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells|
C Buecker, HH Chen, JM Polo, L Daheron, L Bu, TS Barakat, P Okwieka, ...
Cell stem cell 6 (6), 535-546, 2010
|Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency|
J Hansson, MR Rafiee, S Reiland, JM Polo, J Gehring, S Okawa, W Huber, ...
Cell reports 2 (6), 1579-1592, 2012
|The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL|
W Ci, JM Polo, L Cerchietti, R Shaknovich, L Wang, SN Yang, K Ye, ...
Blood, The Journal of the American Society of Hematology 113 (22), 5536-5548, 2009
|Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming|
E Apostolou, F Ferrari, RM Walsh, O Bar-Nur, M Stadtfeld, S Cheloufi, ...
Cell stem cell 12 (6), 699-712, 2013
|A predictive computational framework for direct reprogramming between human cell types|
OJL Rackham, J Firas, H Fang, ME Oates, ML Holmes, AS Knaupp, ...
Nature genetics 48 (3), 331-335, 2016
|A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo|
LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ...
Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009
|A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation|
A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ...
Nature neuroscience 22 (12), 2087-2097, 2019
|BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms|
S Parekh, JM Polo, R Shaknovich, P Juszczynski, P Lev, SM Ranuncolo, ...
Blood, The Journal of the American Society of Hematology 110 (6), 2067-2074, 2007
|Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas|
JM Polo, P Juszczynski, S Monti, L Cerchietti, K Ye, JM Greally, M Shipp, ...
Proceedings of the National Academy of Sciences 104 (9), 3207-3212, 2007
|Class-switch recombination occurs infrequently in germinal centers|
JA Roco, L Mesin, SC Binder, C Nefzger, P Gonzalez-Figueroa, ...
Immunity 51 (2), 337-350. e7, 2019
|A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters|
K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ...
Cell reports 4 (3), 578-588, 2013